In a dystopian near-future, Detroit, which is now bankrupt and overrun with crime, gives Omni Consumer Products (OCP) control of its struggling police force. The company plans to replace the poor, run-down sections of Old Detroit with the high-end "Delta City," but must first address the city's high crime rate. As an alternative to existing law enforcement, OCP senior president Dick Jones (Ronny Cox) offers the prototype ED-209 enforcement droid, but it accidentally kills a board member during a demonstration. The OCP chairman, nicknamed "The Old Man" (Dan O'Herlihy), decides instead to back Jones' young rival, Bob Morton (Miguel Ferrer), and his experimental cyborg police officer program, "RoboCop.
In 2010, United Nations negotiator Edward Douglas (David Thewlis) survives a plane crash in the Java Sea and is eventually rescued by a passing boat. Aboard, a man called Montgomery (Val Kilmer) tends to him, and after telling him the boat has no radio, he promises Douglas the captain will take him to Timor after dropping him off. However, when they arrive at Montgomery's destination referred to as "Moreau's Island", he instead advises Douglas to stay with him, ostensibly so he can use the radio on the island.
In the year after the success of the RoboCop program and Jones's death, Omni Consumer Products (OCP) has created a new plan to have Detroit default on its debt so that OCP can foreclose on the entire city, take over its government, and replace the old neighborhoods with Delta City, a new planned city center independent of the United States government, enabling them to effectively have an entire city to be controlled by OCP.
Chev Chelios (Jason Statham) is a Chinese-based British hitman, working for a crime syndicate headed by Uglyman (Carlos Sanz). Chelios is contracted by Carlito to kill mafia boss Don Kim (Keone Young) as members of the Triads have been encroaching on Carlito's business. Carlito betrays Chelios by making it appear he assassinated Don Kim on his own, without his authorization. Ricky Verona (Jose Pablo Cantillo), an ambitious small-time criminal uses the opportunity to conspire with Carlito against Chelios; Verona will kill Chelios so the Triads do not retaliate, and then take Chelios's place as Carlito's new hired gun. While Chelios sleeps in his apartment, Verona, his brother Alex (Jay Xcala), and several henchmen break in and inject Chelios with a Chinese synthetic drug which inhibits the flow of adrenaline, slowing the heart and eventually killing the victim. Chelios wakes to find a recording left by Verona showing what he has done.
In Los Angeles, November 2019, retired police officer Rick Deckard (Harrison Ford) is detained by officer Gaff (Edward James Olmos) and brought to his former supervisor, Bryant (M. Emmet Walsh). Deckard, whose job as a "Blade Runner" was to track down bioengineered beings known as replicants and destroy them, is informed that four have come to Earth illegally. As Tyrell Corporation Nexus-6 models, they have only a four-year lifespan and may have come to Earth to try to extend their lives.
The future United States is a dystopic irradiated wasteland known as the Cursed Earth. On the east coast lies Mega-City One, a violent metropolis with 800 million residents and 17,000 crimes reported daily. The only force for order are the Judges, who act as judge, jury and executioner. Judge Dredd is tasked by the Chief Judge with evaluating new recruit Cassandra Anderson, a powerful psychic who failed the aptitude tests to be a Judge.
Several months after the events of The Fly, Veronica Quaife is about to deliver the child she had conceived with scientist Seth Brundle. Anton Bartok, owner of Bartok Industries (the company which financed Brundle's teleportation experiments), oversees the labor. Veronica dies from shock after giving birth to a squirming larval sac, which splits open to reveal a seemingly normal baby boy. The orphaned child, named Martin Brundle, is taken into Bartok's care. Bartok is fully aware of the teleportation accident which genetically merged Seth Brundle with a housefly (a condition that Martin has inherited), and he secretly plans to exploit Martin's unique condition.
Shekhar Subramanium (Khan), a game designer who works for the London-based Barron Industries, has delivered a number of commercial failures; an irate Barron (Tahil) gives him his last chance to develop a successful game. To impress his sceptical son Prateek (Verma), and upon the request of his wife Sonia (Kapoor), Shekhar uses his son's idea that the antagonist should be more powerful than the protagonist. His colleague, computer programmer Jenny (Goswami), uses Shekhar's face as a model for that of the game's protagonist G.One (Technically Good One and in Hindi Jeevan, which means life), while the shape-shifting antagonist Ra.One (Technically Random Access Version One and in Hindi Ravan, a mythical demon) is made faceless. Another colleague, Akashi (Wu), implements the characters' movements. The game, named Ra.One, contains three levels, the final level being the only one in which either character can be killed. Each character possesses a special device – the H.A.R.T (Hertz Amplifying Resonance Transmitter) which gives them their powers. Upon reaching the last level, the characters gain a gun with one bullet; the other character can be killed by this bullet but only if his H.A.R.T is attached.
Told from Igor's perspective, it shows the troubled young assistant's dark origins, his redemptive friendship with the young medical student Victor Frankenstein, and become eyewitnesses to the emergence of how Frankenstein became the man who created the legend we know today. The two's experiments eventually get them into trouble with the authorities and they are near to becoming fugitives as they complete their goals to use science to create life, with Frankenstein's ultimate endgame of creating a man.
Kevin Flynn (Jeff Bridges) is a software engineer, formerly employed by the computer corporation ENCOM, who now runs an arcade bar called Flynn's. He wrote several video games, but another ENCOM engineer, Ed Dillinger (David Warner), stole them and passed them off as his own, earning himself a series of promotions until reaching Senior Executive VP. Having left the company, Flynn attempts to obtain evidence of Dillinger's actions by hacking the ENCOM mainframe, but is repeatedly stopped by the Master Control Program (MCP), an artificial intelligence written by Dillinger. However, since its inception the MCP has become power-hungry, illegally appropriating business and even government programs and absorbing them to increase its own capacities; it informs Dillinger of its plans to subjugate The Pentagon and the Kremlin, and expresses interest in China with its request for Chinese-translation programs, blackmailing Dillinger into compliance with records of his theft of the games.
Astronauts Taylor (Charlton Heston), Landon (Robert Gunner), Dodge (Jeff Burton) and Stewart are in deep hibernation when their spaceship crashes in a lake on an unknown planet after a long near-light speed voyage, during which, due to time dilation, the crew ages only 18 months. As the ship sinks, Taylor finds Stewart dead and her body desiccated. They throw an inflatable raft from the ship and climb down into it; before departing the ship, Taylor notes that the date is November 25, AD 3978, approximately two millennia after their departure in 1972. Once ashore, Dodge performs a soil test and pronounces the soil incapable of sustaining life.
Dr. Lawrence Angelo works for Virtual Space Industries, running experiments in increasing the intelligence of chimpanzees using drugs and virtual reality. One of the chimps escapes using the warfare tactics he was being trained for. Dr. Angelo is generally a pacifist, who would rather explore the intelligence-enhancing potential of his research without applying it for military purposes.
Genetic engineers Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) hope to achieve fame by splicing animal DNA to create hybrids for medical use at the company N.E.R.D. (short for Nucleic Exchange Research and Development). Their work previously yielded Fred, a dog-sized vermiform creature intended as a mate for their female specimen, Ginger. After successfully mating them, Clive and Elsa plan to create a human-animal hybrid that could revolutionize science. Their employers Joan Chorot (Simona Maicanescu) of N.E.R.D. and William Barlow (David Hewlett) forbid them from doing this. Instead, they are to find and extract proteins used for commercial drug production from Fred and Ginger. Clive and Elsa pursue their own agenda in secret. They develop a viable female creature (Abigail Chu).
Set in San Francisco, California, down-on-his-luck Naval aviator Lt. Tuck Pendleton (Quaid) resigns his commission and volunteers for a secret miniaturization experiment. He is placed in a submersible pod and both are shrunk to microscopic size. They are transferred into a syringe to be injected into a rabbit, but the lab is attacked by a rival organization, led by scientist Dr. Margaret Canker (Fiona Lewis), that plans to seize the experiment and steal the miniaturization technology.
In Los Angeles, Lt. Parker Barnes and John Donovan are tracking down a serial killer named SID 6.7 at a restaurant in virtual reality. SID (short for Sadistic, Intelligent, Dangerous - a VR amalgam of the most violent serial killers throughout history) puts Donovan into shock, killing him. The director overseeing the project, before Commissioner Elizabeth Deane and her associate, William Wallace, order the programmer in charge of creating SID, Dr. Darrel Lindenmeyer, to shut down the project. Barnes is a former police officer imprisoned for killing political terrorist Matthew Grimes, who killed Parker's wife and daughter and innocent bystanders. This caused Barnes to become a convicted killer and serve 17 years to life.