In 1996, treasure hunter Brock Lovett and his team aboard the research vessel Akademik Mstislav Keldysh search the wreck of RMS Titanic for a necklace with a rare diamond, the Heart of the Ocean. They recover a safe containing a drawing of a young woman wearing only the necklace dated April 14, 1912, the day the ship struck the iceberg. Rose Dawson Calvert, the woman in the drawing, is brought aboard Keldysh and tells Lovett of her experiences aboard Titanic.
The Titanic was the largest vessel afloat, and was widely believed to be unsinkable. Her passengers included the cream of American and British society. The story of her sinking is told from the point of view of her passengers and crew, principally Second Officer Charles Lightoller (Kenneth More).
In Canada, novelist Yann Martel meets Pi Patel, an Indian immigrant with some knowledge from Pi's late father's friend, known to Pi as "Mamaji", for a good book. Pi tells Yann his life story.
In 1918, the young Jiro Horikoshi longs to become a pilot, but his nearsightedness prevents it. He reads about the famous Italian aircraft designer Giovanni Battista Caproni, and dreams about him that night. In the dream, Caproni tells him that building planes is better than flying them.
On July 20, 1969, astronaut Jim Lovell hosts a party, where guests watch on television as Neil Armstrong takes his first steps on the Moon during Apollo 11. After the party, Lovell, who had orbited the Moon on Apollo 8, tells his wife Marilyn that he intends to walk on the Moon's surface.
Dr. Ryan Stone (Sandra Bullock) is a biomedical engineer aboard the NASA space shuttle Explorer for her first space mission, STS-157. Veteran astronaut Matt Kowalski (George Clooney) is commanding his final mission. During a spacewalk to service the Hubble Space Telescope and Stone's upgrades to the Telescope, Mission Control in Houston warns the team about a Russian missile strike on a defunct satellite, which has inadvertently caused a chain reaction forming a cloud of debris in space. Mission Control orders that the mission be aborted and the crew begin re-entry immediately because the debris is speeding towards the shuttle. Communication with Mission Control is lost shortly thereafter.
On the morning of September 11, 2001, four al-Qaeda terrorists Ziad Jarrah, Saeed al-Ghamdi, Ahmed al-Nami, and Ahmed al-Haznawi pray in their respective hotel rooms before arriving at Newark Liberty International Airport. The quartet wait at a gate after getting through security to board San Francisco-bound United 93. After 40 minutes of delay due to traffic the plane takes off, flown by captain Jason Dahl and first officer Leroy Homer, with all four terrorists on board.
When the Japanese freighter Eiko-maru is destroyed near Odo Island, the Bingo-maru is sent to investigate, only to meet the same fate with few survivors. A fishing boat from Odo is also destroyed, with one survivor. Fishing catches mysteriously drop to zero, blamed by an elder on the ancient sea creature known as "Godzilla". Reporters arrive on Odo Island to further investigate. A villager tells one of the reporters that "something large is going crazy down there" ruining the fishing. That evening, a ritual dance to appease Godzilla is held during which the reporter learns that the locals used to sacrifice young girls. That night, a large storm strikes the island, destroying the reporters' helicopter, and an unseen force destroys 17 homes, kills nine persons and 20 of the villagers' livestock.
Henry Bennett (Ewan McGregor), his physician wife Maria (Naomi Watts), and their three sons Lucas (Tom Holland), Tomas (Samuel Joslin), and Simon (Oaklee Pendergrast) go on a Christmas holiday in 2004 to Khao Lak, Thailand. Arriving on Christmas Eve, they settle in and begin to enjoy the brand new Orchid Beach Resort. Two days later the massive 2004 tsunami inundates the area.
In Cambridge, three animal liberation activists break into a medical research laboratory with the intent of freeing captive chimpanzees. They are interrupted by a scientist, who desperately warns them that the chimps are infected with a highly contagious rage-inducing virus that is spread through blood and saliva. Ignoring the scientist's pleas, the activists release a chimpanzee, who attacks one of them and immediately infects her — leading her to attack and infect everyone else present.
The opening shot is a panorama of Los Angeles, revealing a city where all of the buildings and inhabitants are some form of commercial branding: birds in the form of Bentley logos, Microsoft's butterfly, pedestrians in the shape of the AIM icon, overhead highway signs mounted on Atlantic Records logos, etc. The major characters are revealed in an Altman-esque tableau. The Pringles mascot (voiced by David Fincher) pulls into a restaurant's parking lot and propositions an Esso Girl waitress (voiced by Aja Evans) who is on a smoking break. Two Michelin Man cops in a parked cruiser (voiced by Bob Stephenson and Sherman Augustus) are introduced as they debate the morality of keeping animals in zoos. Across town, Bob's Big Boy (voiced by Joel Michaely) and Haribo (voiced by Matt Winston) are on a tour at the zoo led by a flamboyant Mr. Clean (voiced by Michaely). The two boys hate the tour and hop off the tour train. They soon begin to harass the MGM lion by mooning it and throwing a Coca Cola bottle at it, but they are scolded by the zoo security, the Green Giant.
While visiting the (fictional) Ventana nuclear power plant outside Los Angeles, television news reporter Kimberly Wells (Fonda), her cameraman Richard Adams (Douglas) and their soundman Hector Salas witness the plant going through an emergency shutdown (SCRAM). Shift Supervisor Jack Godell (Lemmon) notices an unusual vibration while grabbing his cup of coffee which he had set down. He then finds that a gauge is misreading and that the coolant is dangerously low (he thought it was overflowing). The crew manages to bring the reactor under control and can be seen celebrating and expressing relief.
Set against the gas tragedy in Bhopal, India in 1984, this human drama examines the irresponsible methods of large corporations and the effects of their actions on common people. The night of the tragedy, poison gas clouds from the Union Carbide factory enveloped an arc of over 20 square kilometers killing over 8,000 people in its immediate aftermath and causing multi-systemic injuries to over 500,000 residents. Lest the neighborhood community be "unduly alarmed", the siren in the factory had been switched off, adding to what would become an enduring disaster of immeasurable proportions. Adding insult to injury, researchers are finding that the future generations of the survivors will continue to suffer through chromosonal damage caused by the leak. This unforgettable story unravels through the eyes of a newlywed couple and their friends as they try to pick up the pieces in the aftermath of the catastrophe.