Nurse Betty is a 2000 American black comedy film directed by Neil LaBute starring Renée Zellweger as a Kansas waitress who suffers a nervous breakdown after witnessing her husband's murder, and starts obsessively pursuing her favorite soap actor (played by Greg Kinnear). Morgan Freeman and Chris Rock play the hitmen who killed her husband and subsequently pursue her to Los Angeles.
For her performance, Zellweger won the Golden Globe Award for Best Actress – Motion Picture Musical or Comedy.
In a small Kansas town, Betty (Renée Zellweger), a kind and considerate diner waitress, is a fan of the soap opera A Reason to Love. She has no idea that her husband, Del (Aaron Eckhart), a car salesman, is having an affair with his secretary and that he intends to leave Betty to pursue a relationship with the secretary. She also doesn't know that her husband supplements his income by selling drugs out of the car dealership. When she calls to leave a message about borrowing a Buick LeSabre for her birthday, her husband tells Betty to take a different car, as the LeSabre (unknown to Betty) has stolen drugs hidden in the trunk.