En Californie, à l'époque de la Ruée vers l'or : Cowpoke, un cow-boy de passage en ville, sauve la vie de Tennessee, un joueur professionnel, en abattant un tueur à la solde d'un de ses rivaux. Les deux hommes, très dissemblables, nouent cependant une amitié réciproque. Tennessee fréquente le saloon d'une belle femme qu'on nomme "la Duchesse" et qui est aussi son amante. Là, une aventurière cupide, autrefois liée à Tennessee, entreprend de séduire Cowpoke. Ce dernier lui promet bientôt un mariage. Mais, les choses s'enveniment... car, Tennessee, afin de préserver son ami, éloigne la jeune femme. Cowpoke se fâche, mais finit par en comprendre les raisons. Les deux hommes se réconcilient. Plus tard, Cowpoke sacrifie sa propre vie pour sauver Tennessee, à nouveau menacé.
Parrish (Ford), a Union Army ex-officer, plans to sell his land to Anchor Ranch and move east with his fiancee, Caroline (May Wynn), but the low price offered by Anchor's crippled owner, Lew Wilkison (Robinson), and the outfit's bully-boy tactics make him think again. When one of Parrish's hands is murdered, he decides to stay and fight, utilizing his war experience.
Former bison hunter and entrepreneur Wyatt Earp (Joel McCrea) arrives in the lawless cattle town of Wichita, Kansas. His skills as a gunfighter make him a perfect candidate for marshal but he refuses the job until he feels morally obligated to bring law and order to this wild town. As with the later film Warlock in 1959, the lawman comes in conflict with his sponsors. His least popular move is to take away the guns of everyone in town, no matter how important. Only when town banker Sam McCoy (Walter Coy) is hit with a personal tragedy does Earp's no-guns edict begin to make sense.
Police Lt. Leonard Diamond is on a personal crusade to bring down sadistic gangster Mr. Brown. He's also dangerously obsessed with Brown's girlfriend, the suicidal Susan Lowell. His main objective as a detective is to uncover what happened to a woman called "Alicia" from the crime boss's past.
Jazz cornetist Pete Kelly (Webb) and his Big Seven are the house band at the 17 Club, a speakeasy in Kansas City in 1927 during Prohibition. New local crime boss Fran McCarg (Edmond O'Brien) wants a percentage of the band's meager earnings. Despite the band's opposition, Kelly wisely gives in.
An anti-communist film about a plot to stir up pro-communist sympathies through an act of terrorism. A young village man foils the plot by infiltrating the communist camp and blowing it up instead.
While traveling from New York City to Mexico, the stylish Lucy Gallant is stranded by a storm in fictitious New City, Texas, where rancher Casey Cole helps find her suitable lodging. The public reaction to her fashions persuades Lucy to sell the contents of her trousseau, and she decides to stay and open a dress shop.
Adventure-seeker Johnny Weissmuller (Johnny Weissmuller) receives a request from Professor Carl Blakely (Selmer Jackson) to collaboratively rescue a certain Professor Dixon (William Blakely) from the Mountain of Explosive Fire in Kirundi. The Kirundi natives belong to a religious tribe worshipping a demon thought to control fire. Pious in nature, they are willing to sacrifice humans just to appease the fire demon, who in fact is Dixon. They are also known to possess mystical items, including a jewel-encrusted sabre.
Adventurer Johnny Weissmuller (Johnny Weissmuller) is roped in by Egyptian archaeologist Ellen Marsten (Jean Byron) to traverse the African jungle of Baku. They seek to rescue an acquaintance, Marro (Benjamin F. Chapman, Jr.), from his captors, pygmies known as the "Moon Men". The Moon Men are devoted to a "Moon Goddess" Oma (Helen Stanton), who is apparently an immortal whose only weakness is sunlight. Marro is chosen to be Oma's chief religious official.
Jim Vaus returns from the war and marries Alice. He struggles to make a living. He was hired by Charles Rumsden to fix a doorbell, and realizes that his client is a mob boss. Alice discovers the source of Jim's income and their relationship was expired and strained to the breaking point. She forces Jim to attend a Billy Graham's Los Angeles Crusade, in her attempt to save their marriage and Jim's soul.