The confessions of a sadomasochistic sexually obsessed patient disclosed as fantasies during Manhattan psychiatrist sessions begin to permeate the troubled doctor's subconscious as erotic dreams. This leads to a heated love affair. At the same time a series of shocking murders occur with evidence suggesting it is her new lover / patient.
Emily Reed (Otis) travels to New York City for an interview with an international law firm, which immediately offers her a job on the condition that she can fly to Rio de Janeiro the following morning. Emily agrees and is introduced to Claudia Dennis (Bisset), one of the firm's top executives. They arrive in Rio to finalize the purchase of a hotel, but angry Claudia must fly to Buenos Aires, Argentina, to meet the man the hotel's owner. Claudia instructs Emily to take her date for the night. While viewing the hotel, Emily sees two locals having animalistic sex, which unnerves her and she returns to her own hotel. She meets Claudia's date; a wealthy man named James Wheeler (Rourke). They have dinner, accompanied by James' bodyguards.
A burglar, Scott Muller (Steven Bauer), teams up with Buddy Calamara (David Caruso), a valet at a high-society restaurant. Buddy keeps an eye on Mickey and Ray Davis, a rich married couple, while Scott robs their home.
Miriam Blaylock (Catherine Deneuve) is a beautiful and dangerous immortal vampire, promising specially chosen humans eternal life as her vampire lovers. As the film begins, her vampire companion is John (David Bowie), a talented cellist whom she married in 18th century France. The film opens in a night club in New York, to a live performance from Bauhaus. There they connect with another young couple who are brought home and fed upon by slashing their throats with a bladed Ankh pendant. The bodies are disposed of by an incinerator in the basement of John and Miriam's elegant New York townhouse, where they pose as a wealthy couple who teach classical music. The only student shown is a young tomboy violinist named Alice Cavender (Beth Ehlers).
San Francisco Assistant District Attorney David Corelli (Caruso) is called to the murder scene of prominent businessman Kyle Medford, found stabbed to death in his home by an antique hatchet. Police detectives Bob Hargrove and Petey Vesko find photographs in Medford's safe of Governor Lew Edwards (Crenna) having sex with a prostitute, later identified as Patrice Jacinto. During questioning, Patrice reveals that she and other women were paid by Medford to have sex with wealthy men at his beach house in Pacifica. She also informs them that the most desired prostitute among the clients was a woman known only as "Jade.
Erika Kohut is a piano professor at a Vienna music conservatory. Although already in her forties, she still lives in an apartment with her domineering mother; her father is a long-standing resident in a psychiatric asylum.
Jake Scully (Craig Wasson) is a struggling actor who has lost his role as a vampire in a low-budget horror movie after his claustrophobia thwarts shooting. He returns home to discover his girlfriend cheating on him, so Scully is left without a place to stay.
A voice over describes how the brain begins to shut down at an altitude of 20,000 feet, the human body unable to survive at such heights. A mountaineering group is shown climbing a cliff face in the snow, until an avalanche causes the rigging to break and they fall to their deaths.
In a luxurious house outside Seoul lives one of the country's richest families: company president Yoon, his wife Baek Geum-ok, their divorced daughter Nami, and son Chul. Yoon is company president but the reins of power are held by his wife Geum-ok, whose aged father was once a powerful businessman, and whom Yoon married for her money and influence. Yoon's private secretary is Joo Young-jak, from humble origins. His current job is making sure a U.S. businessman, Robert Altman, is kept happy with hookers, as part of a major business deal that could prove crucial to the family's fortunes. When Geum-ok sees Yoon having an affair with their Filipina maid, Eva, on her hidden CCTV, she beds Young-jak in revenge. When Chul is arrested for organizing a slush fund for Altman, Geum-ok decides to further punish her husband for his "mistake" in bringing the family's name into public disrepute, by having Eva killed. At the same time, Nami and Young-jak, start an affair. Yoon commits suicide over Eva's death (and takes the blame for his son's activities). After his funeral, Young-jak quits the family, glad to be rid of their influences. He accompanies Eva's coffin to the Philippines, where he is joined on the plane by Nami.
Quills begins during the Reign of Terror, with the incarcerated Marquis de Sade penning a story about the libidinous Mademoiselle Renard, an aristocrat who meets the preeminent sadist in her executioner.
At the beginning, Izna, a porn star (Sunny Leone), is lying dead in the grass, but she says that she wants to ask forgiveness from somebody for her sins. The story flashes back six months.
Corky (Gina Gershon), an ex-con who has just finished a five-year jail sentence, arrives at an apartment building to start work as a painter and plumber. On her way up to the apartment, she encounters the couple who live next-door, Violet (Jennifer Tilly) and Caesar (Joe Pantoliano). After Caesar has gone out, Violet flirts with Corky and asks her to help retrieve an earring that has fallen down her sink. After Corky extracts the earring, Violet admits she lost it on purpose in order to get closer to Corky, and starts to seduce her. They are interrupted by the arrival of Caesar and Corky goes back to work. When she leaves for the day, Violet follows her to her truck. They go to Corky's apartment and have sex. The next morning, Violet tells Corky that Caesar is a money launderer for the Mafia and they have been together for five years.
Psychologist Dr. Sarah Taylor (Rebecca De Mornay) is a guarded, aloof criminal psychologist who interviews a client who is a rapist, and is pleading not guilty by reason of insanity. It is later revealed that she was the subject of daily rapes as a child by her estranged father, who is now shown to be very ill. Sarah meets Tony Ramirez (Antonio Banderas) in a shopping mall, and she gives him her number. She begins a relationship with Tony, despite the creepy advances of her neighbor, Cliff (Dennis Miller), with whom she once had a one-night stand.
The title of the film refers to the duration of a relationship between Wall Street arbitrageur John Gray (Mickey Rourke) and divorced SoHo art gallery employee Elizabeth McGraw (Kim Basinger). John initiates and controls the various experimental sexual practices of this volatile relationship to push Elizabeth's boundaries. In doing so, Elizabeth experiences a gradual downward spiral toward emotional breakdown.
Architect and happily married man Evan Webber (Keanu Reeves) has the house to himself and his dog Monkee on Father's Day weekend (due to a shoulder injury) while his wife and children go on a family-planned beach trip. His wife Karen (Ignacia Allamand), a successful artist, leaves their assistant Louis (Aaron Burns) in charge of her sculpture that needs to be moved to an art gallery. Alone in his beautiful and expensive home, Evan works on renderings for an ongoing house project.