The opening scene shows the troops of Agamemnon of Mycenae ready to fight against the troops of Triopas of Thessaly. Afterwards, Prince Hector of Troy and his younger brother Paris negotiate a peace treaty with Menelaus, king of Sparta, and celebrate the end of a long and bloody war. Paris, however, is having a secret love affair with Menelaus' wife, Queen Helen, and smuggles her aboard their homebound vessel, much to Hector's fury, as this could lead to war between Troy and Greece. Upon learning of this, Menelaus meets with his elder brother, King Agamemnon of Greece, and asks his help in taking Troy. Agamemnon, who has wanted to conquer Troy for a long time, agrees, since it will give him control of the Aegean Sea. On King Nestor's advice, Agamemnon has Odysseus, King of Ithaca, persuade Achilles to join them. Achilles, who strongly dislikes Agamemnon and his ways, initially refuses, but eventually decides to go after his mother, Thetis, tells him that though he will die, he will be forever remembered.
In AD 180, Spanish-Roman General Maximus Decimus Meridius leads the Roman army to a decisive victory against the Germanic tribes near Vindobona, ending a long war on the Roman frontier and winning the favor of the Emperor Marcus Aurelius. Maximus, weary of battle, decides to retire at his Spanish farm estate at the Emperor's behest, but the Emperor tells him that his son and heir to the throne, Commodus, is unfit to rule and thus appoints him as regent to help save Rome from corruption. Before he makes his decision, Commodus is confronted by his father who tells him that he will not be emperor. Burdened by grief and believing he was never valued by his father, Commodus kills him.
One year after the famed Battle of Thermopylae, Dilios, a hoplite in the Spartan Army, begins his story by depicting the life of Leonidas I from childhood to kingship via Spartan doctrine. Dilios's story continues and Persian messengers arrive at the gates of Sparta demanding "earth and water" as a token of submission to King Xerxes; the Spartans reply by killing and kicking the messengers into a well. Leonidas then visits the Ephors, proposing a strategy to drive back the numerically superior Persians through the Hot Gates; his plan involves building a wall in order to funnel the Persians into a narrow pass between the rocks and the sea. The Ephors consult the Oracle, who decrees that Sparta will not go to war during the Carneia. As Leonidas angrily departs, a messenger from Xerxes appears, rewarding the Ephors for their covert support.
As a young boy, Noah witnesses his father, Lamech, killed by a young Tubal-cain. Many years later an adult Noah is living with his wife Naameh and their sons Shem, Ham, and Japheth. After seeing a flower grow instantly from the ground and being haunted by dreams of a great flood, Noah takes them to visit his grandfather Methuselah.
Queen Gorgo of Sparta tells her men about the Battle of Marathon, in which King Darius I of Persia was killed by General Themistocles of Athens 10 years earlier. Darius' son, Xerxes, witnesses his father's death, and is advised to not continue the war, since only "the gods can defeat the Greeks". Darius' naval commander, Artemisia, claims that Darius' last words were in fact a challenge and sends Xerxes on a journey through the desert. Xerxes finally reaches a cave and bathes in an otherworldly liquid, emerging as the 8-feet tall "God-King". He returns to Persia and declares war on Greece to avenge his father.
Perseus (Sam Worthington), a son of Zeus (Liam Neeson), lives as a fisherman after the death of his wife, Io (portrayed by Gemma Arterton in the previous film), with his young son, Helius (John Bell). Zeus visits Perseus and asks for his help, saying that humans are not praying to the gods and as a result the gods are losing their power and becoming mortal. Perseus realizes the walls of Tartarus are crumbling and Zeus informs him that the imprisoned Titan Kronos will soon be free. Perseus, valuing his family's safety, refuses to get involved.
In 1300 BC, Moses, a general and member of the royal family, prepares to attack the Hittite army with Prince Ramesses. A High Priestess of Sekhmet (the war goddess) divines a prophecy from animal intestines, which she relates to Ramesses' father, Seti I. He tells the two men of the prophecy, in which one (of Moses and Ramesses) will save the other and become a leader. During the attack on the Hittites, Moses saves Ramesses' life, leaving both men troubled. Later, Moses is sent to the city of Pithom to meet with the Viceroy Hegep, who oversees the Hebrew slaves. Upon his arrival, he encounters the slave Joshua, who is the descendant of Joseph, and Moses is appalled by the horrific conditions of the slaves. Shortly afterwards, Moses meets Nun, who informs him of his true lineage; he is the child of Hebrew parents who was sent by his sister Miriam to be raised by Pharaoh's daughter. Moses is stunned at the revelation and leaves angrily. However, two Hebrews also overhear Nun's story and report their discovery to Hegep.
In the timeframe of 10,000 BC, a tribe of hunter-gatherers called the Yagahl live in a remote mountain range in the Urals and survive by killing woolly mammoths, which they call "mannaks". The camp is led by a hunter who has proven his bravery by killing a Mammoth, and taking the White Spear. The people also strongly venerate an elderly woman, called Old Mother. Because of her different appearance to other humans in the village, it is assumed she is a Neanderthal, the "last of her kind", living with the Homo sapiens of the camp.
Hercules (Dwayne Johnson) is the leader of a band of mercenaries comprising the spear-wielding prophet Amphiaraus (Ian McShane) of Argos, the knife-throwing thief Autolycus (Rufus Sewell) of Sparta, the feral warrior Tydeus (Aksel Hennie) of Thebes, the Amazon archer Atalanta (Ingrid Bolsø Berdal) of Scythia and his nephew storyteller Iolaus (Reece Ritchie) of Athens. Hercules is said to be the demigod son of Zeus, who completed the legendary Twelve Labors, only to be betrayed by Hera who drove him insane and caused him to murder his wife Megara (Irina Shayk) and their children during a visit to King Eurystheus (Joseph Fiennes). Throughout the film, it is not clearly established that Hercules is truly the son of Zeus, and many are skeptical of the claim as well as of the stories of Hercules' famous Twelve Labors. Despite this, Hercules is frequently seen displaying unusual strength and nigh-unmatched skill in combat. Hercules is frequently haunted by the memory of the deaths of his wife and daughters by his hand, as well as visions of Cerberus.
In ancient times after defeating their predecessors, the Titans, the gods divided the Universe among themselves. Zeus took the skies, Poseidon took the seas, and Hades was left with the Underworld upon being tricked by Zeus. The gods created the mortals, whose faith and prayers assured the gods' immortality. As time passed, however, mortals began to question them and soon resist their creators, angering the Olympians.
Before the dawn of man or beast, immortals waged war against each other in Heaven. The victors declared themselves gods while the vanquished were renamed the Titans and imprisoned beneath Mount Tartarus. The Epirus Bow, a weapon of immense power, was lost on Earth during the war. In 1228 B.C., the mortal king Hyperion (Mickey Rourke) of Heraklion searches for the bow, intending to use it to release the Titans to get revenge on the gods for failing to save his family. Hyperion captures the virgin oracle Phaedra (Freida Pinto), believing that she can use her visions to find the Epirus Bow's resting place.
Arthur (Clive Owen) is portrayed as a Roman cavalry officer, also known as Artorius Castus, the son of a Roman father and a Celtic mother, who commands a unit of Sarmatian auxiliary cavalry in Britain at the close of the Roman occupation in 467 A.D. Arthur is loyal to Rome and a devout Catholic, but follows the teachings of Pelagianism, which many consider heretical. He and his men guard Hadrian's Wall against the Woads, a group of native Britons who are rebels against Roman rule, led by the mysterious Merlin (Stephen Dillane).
The film is based on the life of Alexander the Great, King of Macedonia, who conquered Asia Minor, Egypt, Persia and part of ancient India. Shown are some of the key moments of Alexander's youth, his invasion of the mighty Persian Empire and his death. It also outlines his early life, including his difficult relationship with his father Philip II of Macedonia, his strained feeling towards his mother Olympias, the unification of the Greek city-states and the two Kingdoms (Macedonia and Epirus) under the Hellenic League, and the conquest of the Persian Empire in 331 BC. It also details his plans to reform his empire and the attempts he made to reach the end of the then known world.
In AD 26, Judah Ben-Hur (Charlton Heston) is a wealthy prince and merchant in Jerusalem, who lives with his mother, Miriam (Martha Scott); his sister, Tirzah (Cathy O'Donnell); their loyal slave, Simonides (Sam Jaffe); and his daughter, Esther (Haya Harareet), who loves Ben-Hur but is betrothed to another. His childhood friend, the Roman citizen Messala (Stephen Boyd), is now a tribune. After several years away from Jerusalem, Messala returns as the new commander of the Roman garrison. Messala believes in the glory of Rome and its imperial power, while Ben-Hur is devoted to his faith and the freedom of the Jewish people.
Astérix and Obélix have to win the Olympic Games in order to help their friend Lovesix (Stéphane Rousseau) marry Princess Irina (portrayed by Vanessa Hessler). Brutus (Benoît Poelvoorde) uses every trick in the book to have his own team win the game, and get rid of his father Julius Caesar (Alain Delon) in the process, but fails.