Reporter Brad MacKay investigates the murder on the District Attorney who had tried to prosecute a syndicate that is involved in sleeze and local corruption. He has been using an undercover assistant DA Walker.
Frank Thompson (Burgess Meredith), awakens in the middle of the street, after wreckage falling from a building in New York City hits him in the head. Frank soon discovers that his apartment has been rented out for a year and his wife Virginia has been living on her own elsewhere.
Bob Randall (Greene), a war correspondent with a fictional London newspaper, the Gazette, is evacuated with British troops from the beaches of Dunkirk. He writes a hard-hitting story of his experiences, but it is killed by the censor (Radford).
An elderly baker named Miller (Ludwig Stossel) is murdered by a sinister stranger (Peter Lorre). A trail leads on to a nightclub singer, Leda Hamilton (Kaaren Verne) who reveals that she and Miller have been in thrall to an organization of Nazi fifth columnists led by Ebbing (Conrad Veidt). She is helped by a well-meaning sports promoter, Alfred "Gloves" Donahue (Humphrey Bogart), who himself is suspected of murdering a nightclub owner (Edward Brophy), and has to track down those responsible to prove his innocence.
In late 1941, Captain Rick Leland (Humphrey Bogart) is court-martialed and discharged from the U.S. Coast Artillery after he is caught stealing. He tries to join the Canadian Army, but is coldly rebuffed. He subsequently boards a Japanese ship, the Genoa Maru, in Halifax, apparently to make his way to China via the Panama Canal to fight for Chiang Kai-shek.
Le correspondant américain Bill Roberts est une épine dans le pied des nazis, son journal dépeignant toujours le monde sur la vérité sur l'Allemagne. Le Capitaine de la Gestapo Carl Von Rau veut boucher la fuite et assigne Karen Hauen, à qui il s’attache au mariage. Roberts obtient ses informations pour ses récits et ses émissions d'un collectionneur de timbres âgé qui, opposé aux nazis par défi, vend les timbres "appropriés" à Roberts et lui fournit les informations. Attirée par Karen, Roberts l'invite dans son appartement où elle découvre son secret. La vieille philatéliste est envoyée dans un camp de concentration, puis Karen apprend qu'il est son père. Elle fait appel à Roberts pour lui demander de l'aide et lui, fidèle au vieil homme et maintenant amoureux de Karen, accepte de l'aider.
Karl Wagner dirige un refuge dans le Bowery, un quartier mal famé de New York. Ce refuge est en fait une couverture rempli de pièces secrètes qui lui servent de quartier général pour monter des cambriolages et des hold-up. Wagner ne s’embarrasse d'aucun scrupule, engage des tueurs pour participer à ces casses et n'hésite pas à s'en débarrasser ensuite. L'argent ainsi récolté lui sert à payer les frais de bouche du refuge mais aussi a combler de cadeaux sa femme, car Wagner à une double vie, à la ville il est le professeur Frederick Brenner, éminent psychologue. Alors que la police manque de pistes, tout se complique quand Richard, élève de Brenner et petit ami de Judy, (l'assistante de Wagner) est éconduit par cette dernière. Pour la reconquérir il se déguise en clochard et vient chercher de la soupe dans le refuge, il y croise Wagner et comprend alors que Wagner et Brenner sont la même personne. Wagner n'a plus qu'une solution se débarrasser de Richard. Le lendemain la famille de Richard s'inquiète, téléphone à Judy qui dit l'avoir aperçu au refuge... La police peut alors remonter la piste.
At the Central Park Zoo in Manhattan, New York City, Serbian-born fashion designer Irena Dubrovna makes sketches of a black panther. She catches the attention of marine engineer Oliver Reed, who strikes up a conversation. Irena invites him to her apartment for tea. As they walk away, one of Irena's discarded sketches is revealed as a panther impaled by a sword.
On the day of Alice Wentworth’s wedding, mad scientist Dr. Lorenz sends the young bride a poisoned orchid, the scent of which places the young woman in a state of suspended animation. He then spirits her body away to the basement laboratory of his isolated mansion and extracts her bodily fluids to inject into his vain and aged wife in order to renew her youth and beauty.
Johnny Eager (Robert Taylor) masquerades as a taxi driver for his gullible parole officer, A. J. Verne (Henry O'Neill), but in reality, he is the ruthless head of a powerful gambling syndicate. Verne introduces him to socialite Lisbeth "Liz" Bard (Lana Turner), a sociology student. Johnny and Liz are attracted to each other, but then he discovers that she is the stepdaughter of his longtime nemesis, John Benson Farrell (Edward Arnold). As a crusading prosecutor, Farrell was responsible for sending Johnny to prison, and now as the district attorney, he has gotten an injunction preventing Johnny's expensive dog racing track from opening.