Thomas Hutter lives in the fictitious German city of Wisborg. His employer, Knock, sends Hutter to Transylvania to visit a new client named Count Orlok. Hutter entrusts his loving wife Ellen to his good friend Harding and Harding's sister Annie, before embarking on his long journey. Nearing his destination in the Carpathian mountains, Hutter stops at an inn for dinner. The locals become frightened by the mere mention of Orlok's name and discourage him from traveling to his castle at night, warning of a werewolf on the prowl. The next morning, Hutter takes a coach to a high mountain pass, but the coachmen decline to take him any further than the bridge as nightfall is approaching. A black-swathed coach appears after Hutter crosses the bridge and the coachman gestures for him to climb aboard. Hutter is welcomed at a castle by Count Orlok. When Hutter is eating dinner and accidentally cuts his thumb, Orlok tries to suck the blood out, but his repulsed guest pulls his hand away.
Charlotte, a young woman, is abducted by Baron Meier Link, a vampire nobleman who is known not to harm humans needlessly. Charlotte's father hires D, a dhampir, to find her and kill her humanely if she turns into a vampire. At the same time, her older brother also hires the notorious Marcus brothers for backup. Among them is a woman named Leila, who hunts vampires because of a personal grudge rather than for monetary gain. The two parties (D and the Marcus brothers) race inexorably after Meier Link. However, Meier Link hires the mutant Barbarois; a group of lethal mercenary body guards. They consist of Caroline, a shape shifter; Benge, a shadow manipulator; and Machira, a werewolf.
In 1462, Vlad Dracula, a member of the Order of the Dragon, returns from a victory against the Turks to find his wife, Elisabeta, has committed suicide after receiving a false report of his death. Enraged that his wife is now damned for committing suicide, Dracula desecrates his chapel and renounces God, declaring that he will rise from the grave to avenge Elisabeta with all the powers of darkness. In a fit of rage, he stabs the chapel's stone cross with his sword and drinks the blood which pours out of it.
Jonathan Harker is an estate agent in Wismar, Germany. His boss, Renfield, informs him that a nobleman named Count Dracula wishes to buy a property in Wismar, and assigns Harker to visit the count and complete the lucrative deal. Leaving his young wife Lucy behind in Wismar, Harker travels for four weeks to Transylvania, to the castle of Count Dracula. He carries with him the deeds and documents needed to sell the house to the Count. On his journey, Jonathan stops at a village, where locals plead for him to stay clear of the accursed castle, providing him with details of Dracula's vampirism. Harker ignores the villagers’ pleas as superstition, and continues his journey unassisted ascending the Borgo Pass. Harker arrives at Dracula's castle, where he meets the Count, a strange, ancient, almost rodent-like man, with large ears, pale skin, sharp teeth, and long fingernails.
Renfield is a solicitor traveling to Count Dracula's castle in Transylvania on a business matter. The people in the local village fear that vampires inhabit the castle and warn Renfield not to go there. Renfield refuses to stay at the inn and asks his carriage driver to take him to the Borgo Pass. Renfield is driven to the castle by Dracula's coach, with Dracula disguised as the driver. En route, Renfield sticks his head out the window to ask the driver to slow down, but sees the driver has disappeared; a bat leads the horses.
Lawrence Talbot (Lon Chaney, Jr.) is making an urgent call from London to a Florida railway station where Chick Young (Bud Abbott) and Wilbur Grey (Lou Costello) work as baggage clerks. Wilbur answers the phone and Talbot tries to impart to him the danger of a shipment due to arrive for the "McDougal House Of Horrors" (a local wax museum) which purportedly contains the actual bodies of Count Dracula (Béla Lugosi) and the Frankenstein Monster (Glenn Strange). However, before he is able to warn Wilbur, a full moon rises and Talbot transforms into a werewolf, who proceeds to destroy his apartment while Wilbur is on the line. Wilbur, thinking the call is just a prank, hangs up and continues on with his work day. Immediately thereafter, the actual Mr. McDougal (Frank Ferguson) shows up to claim the shipments and, fearing them damaged when Wilbur and Chick mishandle them, demands that the crates be delivered in person so his insurance agent can inspect them.
Lucy Westenra's sister Mina bids farewell to her fiancé Jonathan Harker, who is leaving for a business trip. Harker, a solicitor, is travelling to Count Dracula's castle in Transylvania to expedite his purchase of Carfax Abbey and other properties in England.
In May 1885, Jonathan Harker arrives at the castle of Count Dracula near Klausenburg (Cluj), to take up his post as librarian. Inside, he is startled by a young woman who claims she is a prisoner and begs for his help. Dracula then appears to greet Harker and guide him to his room, where he locks him in. Jonathan starts to write in his diary, and his true intentions are revealed: he is a vampire hunter and has come to kill Dracula.
In the aftermath of the death of Dracula's wife Martha (Jackie Sandler) at the hands of an angry mob, Count Dracula (Adam Sandler) designs and builds a massive five-star hotel in Transylvania in which to raise his daughter Mavis (Selena Gomez) and to serve as a getaway for all the world's monsters.
Renfield, a solicitor, makes a journey into Transylvania via stagecoach. He mentions his destination, Castle Dracula, to the locals who react with alarm. They tell him Count Dracula is a vampire and when he doesn't believe them, one insists he wear a cross. When he arrives at the Castle, the Count bids him welcome. After drinking drugged wine, Renfield drops the cross and is bitten.
While walking her guard rounds in the country, 17-year-old Doris Lang, the daughter of a deceased werewolf hunter, is attacked by Count Magnus Lee, a 10,000-year-old, long-lost vampire lord (also known as a Noble), who intends to make her his new vampire bride.
The film is about a woman who experiences frightening visions after visiting an insane asylum where one of the inmates claims to be Count Dracula (here following the Hungarian spelling Drakula). She has trouble determining whether the inmate's visions are real or merely nightmares.
In 1921, German director Frederich Wilhelm Murnau takes his cast and crew on-location in Czechoslovakia to shoot Nosferatu, an unauthorized version of Bram Stoker's novel Dracula. Murnau keeps his team in the dark about their schedule and the actor playing the vampire Count Orlok. It is left to the film's other main actor, Gustav von Wangenheim, to explain that the lead is an obscure German theater performer named Max Schreck, who is a character actor. To involve himself fully in his role, Schreck will only appear amongst the cast and crew in makeup, and will never break character.
The Monster Squad is a society of young pre-teens who idolize classic monsters and monster movies and hold their meetings in a tree clubhouse. Club leader Sean (Andre Gower), whose five-year-old sister Phoebe (Ashley Bank) desperately wants to join the club, is given the diary of legendary monster hunter Dr. Abraham Van Helsing (Jack Gwillim), but his excitement abates when he finds it is written in German. Sean, his best friend Patrick (Robby Kiger), and the rest of the Monster Squad visit an elderly man, known as the "Scary German Guy" (Leonardo Cimino), actually a kind gentleman, to translate the diary. When the Monster Squad wonders how the German man is so knowledgeable about Van Helsing's battle with monsters, he wryly comments that "he has some experience with monsters" and his shirt sleeve briefly reveals a Concentration camp number tattoo.
Scooby-Doo, Shaggy, and Scrappy-Doo are on their way to a Miss Grimwood's Finishing School for Girls, where they have been hired as gym teachers. Once there, however, they find that it is actually a school for girl ghouls. The pupils include Sibella, the daughter of Count Dracula; Elsa Frankenteen, the daughter of Frankenstein's monster, Winnie, the daughter of The Wolfman; Phantasma (usually called Phanty for short), the daughter of a phantom, possibly The Phantom of the Opera; and Tanis, the daughter of The Mummy - all parodies/tributes to the Universal Monsters of the 1930s-40s. Other residents of the school are a floating white hand; an octopus, who is the school's butler; Legs, a spider that helps with the upcoming volleyball match; Miss Grimwood, the headmistress; and her pet dragon Matches (who dislikes Scooby at first, but later becomes friends, and has a strong friendship with Scrappy). Shaggy and Scooby want no part of this at first, but eventually they agree to stay as teachers.