Alors qu'il doit libérer la fille d'un homme d'affaires richissime incarcérée dans une prison lettonne de haute sécurité, Ray Breslin apprend que sa petite amie, Abigail, a été kidnappée par le fils d'un ancien allié devenu son ennemi juré. Désormais, Breslin doit sauver les deux femmes enfermées dans ce pénitencier surnommé The Devil's Station car personne n'en est jamais sorti vivant. Secondé par Trent DeRosa et Hush, Breslin doit faire vite pour organiser leur évasion...
Des années après s'être échappé d'une prison high-tech surnommée « Le tombeau », Ray Breslin dirige désormais une équipe d’élite spécialisée pour faire évader des gens des prisons les plus impénétrables du monde. Shu Ren, son meilleur agent, est emprisonné dans un labyrinthe techno-terroriste informatisé et révolutionnaire connu sous le nom d'Hadès (H.A.D.E.S. pour High Asset DEtention Service ou HAvre de Détention et Sécurité en français), où les prisonniers se battent dans des luttes mortelles. Ray Breslin décide alors de s'y faire incarcérer pour le sauver.
En 1943, près du village de Sobibór dans le Gouvernement général de Pologne, un train de déportés juifs s'arrête devant l'entrée du camp d'extermination. Ce camp est un des maillon de l'Aktion Reinhard. Les déportés sont débarrassés de leurs bagages. Ceux qui déclarent avoir une profession jugée utile sont séparés des autres. Un groupe de prisonniers organise un soulèvement et une évasion à grande échelle.
En 1930, Henri Charrière, surnommé « Papillon Pouce-coupé », » est condamné à perpétuité au bagne en Guyane pour meurtre alors qu'il clame son innocence. Il est d'abord envoyé au bagne de Saint-Laurent-du-Maroni en 1933 (où il rencontre Louis Delga), puis sur l'île Saint-Joseph ou sur l'île du Diable. Papillon n'a alors qu'une idée en tête : l'évasion.
Ray Breslin is a former prosecutor who co-owns Breslin-Clark, a Los Angeles–based security firm specializing in testing the reliability of maximum security prisons. He spends his life getting into prisons to study their designs and the guards' habits to find and exploit their weaknesses, thus enabling him to escape without a hitch or a victim. His goal is to ensure that criminals sent to prison stay inside by eliminating the weakness of every prison; Breslin's wife and child were murdered by an escaped convict he had successfully prosecuted.
During World War II, after the Soviet invasion of Poland, young Polish military officer Janusz Wieszczek (Jim Sturgess) is held as a POW and interrogated by the NKVD. The Soviets, unable to get him to say he is a spy, take into custody his wife from whom they extort a statement condemning him. He is sentenced to 20 years in a Gulag labour camp deep in Siberia.
Andy, now 17 years old, is about to leave for college, and his toys have not been played with for years. He intends to take only Woody with him, and puts Buzz Lightyear, Jessie and the other toys in a bag to be stored in the attic. Andy's mother mistakenly takes the bag to the curb for garbage pickup. The toys escape and, believing Andy intended to throw them away, decide to climb in a donation box with Barbie bound for Sunnyside Daycare. Woody follows them and tries to explain the mistake, but they refuse to believe him.
Steven Jay Russell (Jim Carrey) is on his deathbed, recalling the events of his life that led him to this point. He spent his early adult years in Virginia Beach as a police officer. He plays the organ at church, has unenthusiastic sex with his wife, Debbie (Leslie Mann), and spends his off hours searching for his biological mother, who placed him for adoption as a child. Steven locates his biological mother, but she rejects him.
Set in 1931, two sisters, 14-year-old Molly and 8-year-old Daisy, and their 10-year-old cousin Gracie live in the Western Australian town of Jigalong. The town lies along the northern part of Australia's rabbit-proof fence, which runs for several thousand miles.
During World War II, U.S. Army intelligence officer First Lieutenant Thomas Hart (Farrell) is captured by German forces. While interrogating Hart, the Germans coerce him to divulge intelligence by taking away his boots, causing his feet to become frostbitten and badly injured, and leaving him, naked, in a very cold cell. He is then transferred by train to Stalag VI-A prisoner of war camp at Hemer, Germany. While en route, a P-51 Mustang attacks (the letters POW were painted on the top of the train, but got covered by thick snow). To save themselves, the POWs leave the train and spell P-O-W with their bodies and prevent further strafing.
Three convicts, Ulysses Everett McGill (George Clooney), known as Everett, Pete Hogwallop (John Turturro) and Delmar O’Donnel (Tim Blake Nelson) escape from a chain gang and set out to retrieve the $1.2 million that Everett buried. The three get a lift from a blind man driving a handcar on a railway. He tells them that they will find a fortune, but not the one they seek. The trio make their way to Pete’s cousin Wash’s house. They remove their chains and sleep in the barn, but Wash betrays them and they are woken by policemen led by Sheriff Cooley, who have them surrounded. The police try to smoke them out, but Wash’s son rescues them.
A career bank robber, Jack Foley (George Clooney), and a U.S. Marshal, Karen Sisco (Jennifer Lopez), are forced to share a car trunk during Foley's escape from a Florida prison. After he completes his getaway, Foley is chased by Sisco while he and his friends—right-hand man Buddy (Ving Rhames) and unreliable associate Glenn (Steve Zahn)—work their way north to Bloomfield Hills, a wealthy northern suburb of Detroit. There they plan to pay a visit to shady businessman Ripley (Albert Brooks), who foolishly bragged to them in prison years before about a cache of uncut diamonds hidden in his home.
In 1947 Portland, Maine, banker Andy Dufresne is convicted of murdering his wife and her lover and sentenced to two consecutive life sentences at the fictional Shawshank State Penitentiary in rural Maine. Andy befriends prison contraband smuggler, Ellis "Red" Redding, an inmate serving a life sentence. Red procures a rock hammer and later a large poster of Rita Hayworth for Andy. Working in the prison laundry, Andy is regularly assaulted by the "bull queer" gang "the Sisters" and their leader, Bogs.
Clarice Starling (Jodie Foster) is pulled from her training at the FBI Academy at Quantico, Virginia by Jack Crawford (Scott Glenn) of the Bureau's Behavioral Science Unit. He assigns her to interview Hannibal Lecter, a former psychiatrist and incarcerated cannibalistic serial killer, whose insight might prove useful in the pursuit of a serial killer nicknamed "Buffalo Bill", who skins his female victims' corpses.
In 1912, 13-year-old Indiana Jones is horseback riding with his Boy Scout troop in Moab, Utah. While scouting caves, Indy discovers a group of grave robbers who have found a golden crucifix belonging to Coronado and steals it from them, hoping to donate it to a museum. The men give chase through a passing circus train, leaving Indy with a bloody cut across his chin from a bullwhip and new phobia of snakes. Indy escapes, but the local sheriff makes him return the crucifix. Impressed with Indy's bravery, the leader of the robbers gives Indy his fedora.