Quentin Kemmer (Devon Gummersall) is a shy security guard and obsessive comic book fan who dreams of becoming a superhero like his favorite comic book character The Arachnid Avenger, and going out with his next-door neighbor Stephanie Lewis (Amelia Heinle). When his partner is killed during a botched robbery at the research laboratory where he works, Quentin is fired and he injects himself with an experimental serum derived from spiders. The next day he is wracked with a severely high fever and spends most of the day unconscious. After he recovers he discovers that he has developed increased strength.
Min Lo Chan, un diplomate chinois et ancien ami de Jonah Jameson pendant la seconde guerre, doit prouver qu'il n'est pas un traître à sa nation et demande l'aide de son ancien ami pour prouver ses dires. Mais un industriel américain M. Zeider complote car l'homme pourrait compromettre ses projets en Asie. Il envoie ses hommes de main pour enlever sa fille Emily et faire pression sur le politicien. Peter n'aura d'autre choix que de prendre son identité secrète de Spider-Man pour les affronter. Une aventure qui le conduira jusqu'à Hong Kong...
Peter Parker (Nicholas Hammond), a freelance photographer for the Daily Bugle, is bitten by a radioactive spider and discovers he has gained superpowers, such as super-strength, agility and the ability to climb sheer walls and ceilings. When a mysterious Guru (Thayer David) places people under mind-control to rob banks and threatens to have ten New Yorkers commit suicide at his command unless the city pays him $50 million, Peter becomes the costumed hero Spider-Man to stop the crook's fiendish scheme. Things take a bad turn when the villain hypnotizes Peter Parker into being one of the ten people to jump off a building on command.
Creatures that for years have been rumoured to torment armed forces in the Middle East are inadvertently introduced to the southwestern deserts of the United States. The camel spiders now freely hunt for prey, unafraid of any predator - including man. No place is safe no one is beyond their paralyzing sting. In the end, a small band of hardy fighters are forced to make one last stand against the creatures.
Alex Mathis (Greg Grunberg) is a cash-strapped but good-natured exterminator working in Los Angeles. While helping an elderly woman with a rodent problem, he is bitten by a poisonous spider and is treated at a hospital. Meanwhile, a mortician is bitten by a rodent-sized spider that crawls out of a dead body which just arrived at the hospital. Learning of this, Alex offers to take care of the spider in exchange for clearing his hospital bill. José Ramos (Lombardo Boyar), a hospital security guard, offers to help Alex. Going to the morgue, Alex deduces the spider escaped into an air vent. He enters the vent and communicates with José via walkie-talkie. Meanwhile, a military task force led by Major Braxton Tanner (Ray Wise) and Lieutenant Karly Brant (Clare Kramer) show up at the hospital to examine the dead body the spider burst out of.