A short time after the first film, Mavis (Selena Gomez) and her fiance Johnny (Andy Samberg) are married, with the approval of her father Dracula (Adam Sandler) and the world has become aware of (and unfased by) the existence of monsters. Mavis later reveals to Drac that she is pregnant and a year later, she gives birth to a son named Dennis (Asher Blinkoff), who befriends Wayne's werewolf pup daughter Winnie (Sadie Sandler). Nearing his fifth birthday, Dennis has yet to grow his fangs and Drac worries that his grandson might not gain vampire powers. Noticing the dangers of Transylvania, Mavis starts to consider raising Dennis where Johnny grew up, much to Drac's disapproval.
In the aftermath of the death of Dracula's wife Martha (Jackie Sandler) at the hands of an angry mob, Count Dracula (Adam Sandler) designs and builds a massive five-star hotel in Transylvania in which to raise his daughter Mavis (Selena Gomez) and to serve as a getaway for all the world's monsters.
Scientist Sebastian Caine has developed a serum that can make a subject invisible. His team of scientists, which includes ex-girlfriend Dr. Linda McKay and Dr. Matt Kensington, eventually enable the serum to work on a gorilla and restore it to visibility. Sebastian once again becomes obsessed with Linda while unbeknownst to him, she has become involved with Matt. Instead of reporting his success to the military, Sebastian lies to the oversight committee, which includes his mentor Dr. Howard Kramer, convincing his team to go right into human testing. The procedure is performed on Sebastian. It is successful and Sebastian turns completely invisible. He then enjoys sneaking around the lab in order to scare and play pranks on his fellow co-workers. They become worried that he is taking it too far. After three days, he is unable to revert to visibility.
Quelques mois après Hôtel Transylvanie 2, tous les membres de la famille de Dracula et ses amis se réunissent pour partir en vacances à bord d'un luxueux bateau de croisière. Pendant la croisière, Dracula tombe amoureux du capitaine qui n'est autre que la descendante du professeur Van Helsing, le tristement célèbre tueur de monstres.
The movie opens with the invisible Nick Halloway (Chevy Chase) dictating his memoirs into a video camera. To prove it is not a camera trick, he chews some bubble gum. Nick goes on to narrate the story of how he came to be invisible, beginning a few days earlier at his job as a stock analyst. His secretary, Cathy DiTolla (Rosalind Chao), refers to him as a "bullshit artist", and he spends most of his life avoiding responsibility and connections with other people. At his favorite bar, the Academy Club, his friend George Talbot (Michael McKean) invites him to join his table where Nick meets Alice Monroe (Daryl Hannah), a TV documentary producer. Sharing an instant attraction, Nick and Alice make out in the ladies' room. When Alice has to leave, Nick drinks heavily to console himself, although the pair set a lunch date for Friday.
In the 23rd century, to discover the fate of an expedition sent 20 years earlier, starship C-57D reaches the distant planet Altair IV. Dr. Edward Morbius (Walter Pidgeon), one of the expedition's scientists, contacts the starship. He states no assistance is required, warning the Earth ship away, saying he cannot guarantee their safety. Commander John Adams (Leslie Nielsen) insists on landing.
The grandson of Dr. Jack Griffin, the original invisible man, has emigrated to the United States and now runs a print shop in Manhattan under the assumed name of Frank Raymond (Jon Hall). In his shop he is confronted by four armed men who reveal that they know his true identity. One of the men, Conrad Stauffer (Cedric Hardwicke), is a lieutenant general of the S.S., while a second, Baron Ikito (Peter Lorre), is Japanese. They offer to pay for the invisibility formula and threaten amputation if it is not revealed. Griffin manages to escape with the formula in his hands.
Sir Geoffrey Radcliffe (Vincent Price) is sentenced to death for the murder of his brother Michael, a crime he did not commit. Dr. Frank Griffin, the brother of the original invisible man (named John instead of Jack), injects the prisoner with an invisibility drug. As Radcliffe's execution nears, he suddenly vanishes from his cell. Detective Sampson (Cecil Kellaway) from the Scotland Yard guesses the truth while Radcliffe searches for the real murderer before the drug causes him to go insane.
An eager scientist (John Carradine) tests his new formula for invisibility on an escaped fugitive (Jon Hall). When the formula works the criminal runs off to terrorize a family he believes cheated him out of a fortune years earlier.
The wealthy lawyer Dick Russell (John Howard) funds the dotty old inventor Professor Gibbs (John Barrymore) to create an invisibility device. The first test subject for this machine is Kitty Carroll (Virginia Bruce), a department store model who had been fired from her previous job. The machine proves quite successful, and Kitty uses her invisible state to pay back her former sadistic boss, Mr. Growley (Charles Lane).
On a snowy night, a mysterious stranger, his face swathed in bandages and his eyes obscured by dark goggles, takes a room at The Lion's Head Inn in the English village of Iping in Sussex. The man demands that he be left alone. Later, the innkeeper, Mr. Hall (Forrester Harvey) is sent by his wife (Una O'Connor) to evict the stranger after he makes a huge mess in his room while doing research and falls behind on his rent. Angered, the stranger throws Mr. Hall down the stairs. Confronted by a policeman and some local villagers, he removes his bandages and goggles, revealing that he is invisible. Laughing maniacally, he takes off his clothes, making himself completely undetectable, and drives off his tormenters before fleeing into the countryside.
This film takes place during the events of Get Smart. Bruce and Lloyd have been testing out an invisibility cloak, but during a party, Maraguayan agent Isabelle steals it for El Presidente. Now, Bruce and Lloyd must find the cloak on their own because the only non-compromised agents, Agent 99 and Agent 86 (Max Smart) are in Russia. With no field experience, Bruce and Lloyd must learn how to get a girl and infiltrate the Maraguayan Embassy to prevent Maraguay from selling the cloak to KAOS.
John Lamar buys a Jade Box in Asia but it is stolen by his friend Martin Morgan. A cult, searching for the box because it contains the secret to invisibility, catches up with and abducts Lamar. After discovering the theft, the cult send a message to Martin and the pair's children: John Lamar's son, Jack, who is engaged to Martin Morgan's daughter, Helen. Jack searches for the Box while Martin attempts to discover the secret of invisibility for his own schemes.
Federal Communications Commission (FCC) investigators arrive in the San Fernando Valley after what appears to be a UFO crashes, causing massive interference with teleradio transmissions. During their investigation they receive witness reports of what appears to be a man dressed in a bizarre outfit. Their investigation uncovers that this is a being from outer space who is invisible. They start a massive manhunt, causing a public panic over the invisible alien running loose.
Former U. S. Army major, Paul Krenner (James Griffith), plans to conquer the world with an army of invisible soldiers and will do anything to achieve that goal. With the help of his hired muscle, Julian (Red Morgan), Krenner forces Dr. Peter Ulof (Ivan Trisault) to perfect the invisibility machine Ulof invented. He keeps Ulof’s daughter, Maria (Carmel Daniel) imprisoned to keep Ulof in line.