In 2009, American geologist Adrian Helmsley visits astrophysicist Satnam Tsurutani in India and learns that neutrinos from a massive solar flare are causing the temperature of the Earth's core to rapidly increase. Arriving at a party in Washington, D.C, Helmsley presents his information to White House Chief of Staff Carl Anheuser, who takes him to meet the President.
When a star gone supernova threatens to destroy the Earth, an astrophysicist puts together a dangerous and desperate plan to shield the Earth from the destructive burst of radiation heading toward it.
In Cambridge, three animal liberation activists break into a medical research laboratory with the intent of freeing captive chimpanzees. They are interrupted by a scientist, who desperately warns them that the chimps are infected with a highly contagious rage-inducing virus that is spread through blood and saliva. Ignoring the scientist's pleas, the activists release a chimpanzee, who attacks one of them and immediately infects her — leading her to attack and infect everyone else present.
During the original outbreak of the Rage Virus, Don, his wife Alice, and four other survivors hide in a barricaded cottage on the outskirts of London. They hear a terrified boy pounding at their door, and let him in. A few minutes later, they discover that the infected have followed the boy to them. The infected attack and kill most of the survivors, while Don, Alice, and the boy are chased upstairs. Don is separated from Alice and when the boy is seen hiding in the closet. Alice rushes to get the boy, while Don tells her to just leave him. Soon the infected break into the room and after Alice pleading with Don to "help us", he decides to leave, abandoning them. Don desperately sprints to a nearby motorboat and narrowly escapes.
Set in New York City, the film focuses on the relationship between two people as they await the end of all life on Earth. Scientists and theologians alike have predicted that by the next morning at 4:44 a.m. Eastern Standard Time deadly solar and cosmic radiation will destroy the Earth's protective ozone layer, and along with it, all life on the planet. Mixed in throughout the film are news clips of various reporters, commentators and celebrities who contemplate what the end of the world will be like.
Columbia Air Lines' Flight 409 is a Boeing 747-100 on a red-eye route from Washington Dulles International Airport to Los Angeles International Airport. Scott Freeman, meanwhile, is a New Mexican businessman flying his private Beechcraft Baron to an urgent sales meeting in Boise, Idaho. However, an occluded front has the entire West Coast socked in, with Los Angeles reporting zero visibility. Columbia 409 and Freeman's Beechcraft are both diverted to Salt Lake City International Airport.
During the closing days of the Second World War, six members of his Royal Canadian Air Force fighter squadron are killed due to a command decision made by pilot Ted Stryker (Dana Andrews). Years later, in civilian life in Ottawa, Ontario, Canada, a guilt-stricken Stryker goes through many jobs, and his marriage is in trouble.
A local field researcher named Marshall Clarke (Simon Bossell) is investigating the disappearance of local wildlife, and finds slimy residue on a fence post. Meanwhile, a woman named Amy Harding (Pamela Gidley) moves into her old cabin in the woods of Langdon, where she spent her family holidays as a child, along with her cat, Frankie, and two goldfishes. In the morning, Amy cleans, and fixes up her cabin. She goes to eat some cake, and discovers that something has been in it. Outside, she meets Mr. Peterson (Norman Forsey), looking for his dog Florence, which was killed by an unseen creature, he tells her to get out of Langdon.
Three travelers, Gringo, Ariel, and Pollo travel through Chile. They party in a club and meet three young women, sisters Monica and Kylie, and their Russian friend Irina. The two groups pair up and decide to travel down to Valparaiso together.
While Dori Thorell (Sharon Lawrence) and her 9-year-old son, Danny (Michal Suchánek), eat breakfast, Sam Thorell (Garwin Sanford) calls from his business trip. Ballerina Diane Agostini (Jennifer Garner) is on the phone with her father when a blender shakes off the counter. Dismissing it, she ends the call and rushes off to a rehearsal session at the New York City Ballet. But she's scolded for being late. Public defender Evie Lincoln (Lisa Nicole Carson) talks with her client Joshua Bingham (JR Bourne) about his case. That evening, tremors cause a gas leak at Diane's apartment complex. Though the electricity is still on in the evacuated building, Fire Chief Thomas Ahearn (Tom Skerritt) sends his crew inside. The building explodes, killing several men. At a party at Gracie Mansion, Evie's grandmother Emily Lincoln (Cicely Tyson) chastises her for being late. Her father, Mayor Bruce Lincoln (Charles S. Dutton), coerces her into going to a job interview at a big law firm.
A chemical weapons catastrophe has wiped out most of mankind and rendered the air un-breathable. The US government hastily built a few makeshift underground bunkers in which a few scientists are kept in cryogenic sleep until the air is no longer toxic. Each of those bunkers is kept up by a couple of maintenance workers who are woken up for two hours every six months in order to perform routine tasks and inspections to keep the facility going.
Un automne, une tempête solaire détruit les satellites du système de l'ACAT, un nouveau programme de lutte contre le terrorisme aérien. Deux avions qui vont à Detroit, l'Air Force One contenant le président et un DC-9 du vol n 23 d'« Americana Bleu » avec des passagers civils, sont sur une même identique trajectoire de collision directe.
Chicago is paralyzed by a snowstorm affecting Lincoln International Airport. A Trans Global Airlines (TGA) Boeing 707 flight crew misjudge their turn off of Runway 29 on to the taxiway, becoming stuck in the snow and closing Runway 29, forcing airport manager Mel Bakersfield (Burt Lancaster) to work overtime. This causes tension with his wife, Cindy (Dana Wynter). Divorce is looming as he nurtures a closer relationship with a co-worker, TGA customer relations agent Tanya Livingston (Jean Seberg). Bakersfield's brother-in-law, Vernon Demarest (Dean Martin), is a TGA captain scheduled to be the checkride captain for TGA to evaluate Captain Anson Harris (Barry Nelson) during TGA's Flight 2 to Rome. Flight 2 is aboard TGA's flagship service craft, a Boeing 707 known as The Golden Argosy. Although Demarest is married to Bakersfield's sister, Sarah (Barbara Hale), he is secretly having an affair with Gwen Meighen (Jacqueline Bisset), chief stewardess on Flight 2, who informs him before the flight that she is pregnant with his child.
Kevin Harrison (Robert Wagner), a corrupt arms dealer, attempts to destroy an American-owned Concorde on its maiden flight after one of the passengers, reporter Maggie Whelan (Susan Blakely), learns of his weapons sales to communist countries during the Cold War.
Motaba, a fictional virus which causes a deadly fever, is discovered in the African jungle in 1967. To keep the virus a secret, U.S. Army officers Donald McClintock (Donald Sutherland) and William Ford (Morgan Freeman) destroy the camp where it was found.