A group of scientists are killed by a mutant named Pluto (Michael Bailey Smith). Later, Bob Carter (Ted Levine) and his wife, Ethel Carter (Kathleen Quinlan) are traveling from Cleveland, Ohio to San Diego, California for their silver anniversary. With them are their teenage children Bobby (Dan Byrd), and Brenda (Emilie de Ravin), eldest daughter Lynn (Vinessa Shaw), Lynn's husband Doug Bukowski (Aaron Stanford), their baby daughter Catherine (Maisie Camilleri Preziosi), and their German Shepherds, Beauty and Beast.
In 1931, the Bondurant brothers—Forrest, Howard and Jack—are running a successful moonshine business in Franklin County, in the Virginia Piedmont region. They use their gas station and restaurant as a front for their illegal activities, and their friend Cricket Pate assists them in their endeavors. One day, Jack witnesses mobster Floyd Banner shooting a competitor, and Jack and Floyd exchange looks.
Ben Shaw (Joshua Jackson) and his new bride, Jane (Rachael Taylor), leave New York for Tokyo, Japan, where Ben has a job as a photographer. While traveling, Jane hits a girl in the middle of the wilderness, running over her. They find no body or even a trace of blood and decide to leave, thinking the victim was all right. They later start to find mysterious lights in their photos, which are later identified as spirit photography by Ben's assistant, Seiko Nakamura (Maya Hazen). Jane begins to have eerie dreams and visions as if they are trying to tell her something, and senses a haunting presence stalking them. Ben begins to complain of severe shoulder pain, and his friends begin to comment he's looking bent and hunched over, though the doctor can find no cause. Seiko takes Jane to her ex-boyfriend, Ritsuo (James Kyson Lee), whose career is to investigate paranormal activities, and he tells them that the lights are spirits, manifestations of intense emotions trying to communicate. At a subway station, Jane spots the ghostly presence of the girl she hit, causing her to believe that she killed the girl. Ben later also has a similar terrifying encounter. They go to a medium, Murase; however, Ben refuses to translate what Murase says, claiming he is a fraud.
In 1987, obese, illiterate 16-year-old Claireece Precious Jones (Gabourey Sidibe) lives in the New York City ghetto of Harlem with her dysfunctional, abusive, unemployed mother, Mary (Mo'Nique), who has long subjected her to physical, mental and sexual abuse. Precious has also been raped by her father, Carl (Rodney "Bear" Jackson), resulting in two pregnancies. The family resides in a Section 8 tenement and survives on welfare. Her first child, "Mongo" (short for Mongoloid), has Down syndrome and is being cared for by Precious' grandmother, though Mary forces the family to pretend that Mongo lives with her and Precious so she can receive extra money from the government. When Precious' second pregnancy is discovered, her high school principal arranges for her to attend an alternative school, where she hopes Precious can change her life's direction. Precious finds a way out of her traumatic daily life by escaping into daydreams. In her mind, she has created an alternate world where she is loved and appreciated.
Four Atlanta businessmen, Lewis Medlock (Burt Reynolds), Ed Gentry (Jon Voight), Bobby Trippe (Ned Beatty) and Drew Ballinger (Ronny Cox), decide to canoe down a river in the remote northern Georgia wilderness, expecting to have fun and witness the area's unspoiled nature before the fictional Cahulawassee River valley is flooded by construction of a dam. Lewis, an experienced outdoorsman, is the leader. Ed is also a veteran of several trips but lacks Lewis' machismo. Bobby and Drew are novices.
Two friends, Thelma Dickinson (Geena Davis) and Louise Sawyer (Susan Sarandon), set out for a two-day vacation to take a break from their dreary lives. Thelma is married to a controlling man, Darryl (Christopher McDonald), while Louise works as a waitress in a diner, and is dating a musician who spends most of his time on the road. They head out in Louise's 1966 Ford Thunderbird convertible, but their vacation in the mountains quickly turns into a nightmare before they reach their destination.
Paul Kersey (Charles Bronson) seems to have picked up the pieces of his life and moved on, and is now dating L.A. radio reporter Geri Nichols (played by Bronson's real-life wife Jill Ireland). They go to pick up Kersey's daughter Carol (Robin Sherwood) from the hospital, where her doctor says that despite traumatic catatonia, Carol has begun to speak again. Paul, Geri, and Carol spend the afternoon at a carnival. While waiting in line for ice cream, Paul gets pick-pocketed by five gang members (named Nirvana, PunkCut, Stomper, Cutter and Jiver). He catches up with Jiver, after a brief struggle, denies taking Paul's wallet. Paul lets him go.
Traumatisé par la mort de sa fille, Cory Lambert travaille pour le United States Fish and Wildlife Service dans le Wyoming. Un jour, il trouve le corps d'une adolescente dans une région déserte de la réserve indienne de Wind River. Le FBI envoie alors sur les lieux une jeune agente inexpérimentée, Jane Banner. Rapidement consciente de son ignorance des réalités de ce milieu isolé et hostile, dépassée par les événements violents qui se succèdent, elle engage Cory comme pisteur pour l'aider dans sa tâche.
Set in the late 18th century, the story follows the life of Georgiana Cavendish, Duchess of Devonshire. Well known for her beauty and fashion sense, she is also remembered for her extravagance and gambling habits. Despite the blatant infidelities of her husband, the cold and much older William Cavendish, the 5th Duke of Devonshire, Georgiana thrives, becoming a fashion icon, a doting mother, a shrewd political operator, and darling of the common people. In befriending Lady Bess Foster, Georgiana is crushed when Bess and The Duke begin an affair. Despite Georgiana's anger, the Duke wants Bess to remain living with them. Bess later explains to Georgiana that the reason she began the affair with the Duke was so that she could get her children back. The Duke wants a male heir, which the Duchess has not yet provided. The idea is that Bess can, since she already has three sons, of whom the Duke is very fond, treating them as if they were his own.
Born and raised in a small Tennessee town, Nutbush, Anna Mae Bullock (Tina's original name) grows up in an unhappy family, with her parents later leaving and abandoning her and only taking her sister. Following her grandmother's death, she relocates to St. Louis, reuniting with her mother and close sister Alline. Anna Mae pursues a chance to be a professional singer after seeing charismatic bandleader Ike Turner perform one night. Later she wins her spot in Turner's band after singing onstage and he begins mentoring her. In time, an unexpected romance develops between the two after she moves into Ike's home. Shortly afterwards, they marry and begin having musical success together as Ike and Tina Turner.
A captive woman—forced to breed mutant children—gives birth to a stillborn. She is then killed by mutant leader Papa Hades (Michael Bailey Smith) for being unable to provide healthy offspring. Later, scientists working in the New Mexico desert are attacked by Letch.
Joy Newsome (Brie Larson), also known as Ma, is being held captive with her five-year-old son, Jack (Jacob Tremblay), in a garden shed. It all started when Old Nick (Sean Bridgers) tricked Ma into helping him with his sick dog. She was then kidnapped and brought to "Room", the garden shed in the backyard of Old Nick's house. Seven years later, Ma and Jack find themselves still locked in "Room", itching to get out.
Plastic surgeon Robert Ledgard was successful in cultivating an artificial skin resistant to burns and insect bites, which he calls "GAL", that he says he has been testing on athymic mice. He presents his results in a medical symposium but when he privately discloses he has also conducted illegal transgenic experiments on humans, he is forbidden to continue with his research.
Charlie (Logan Lerman) is uneasy about beginning his freshman year of high school; he is shy and finds difficulty in making friends, but he connects with his English teacher, Mr. Anderson (Paul Rudd).