Three men, Red Pollard (Tobey Maguire), Charles S. Howard (Jeff Bridges), and Tom Smith (Chris Cooper) come together as the principal jockey, owner, and trainer of the championship horse Seabiscuit, rising from troubled times to achieve fame and success through their association with the horse.
During a thunderstorm, a traveling circus accidentally leaves behind a baby zebra. The foal is rescued by widower Nolan Walsh, a former Thoroughbred-racehorse trainer who retired when his wife, a jockey, died in a racing accident. Nolan takes the zebra home to his farm and leaves it under the care of his daughter Channing "Chan" Walsh, who names him "Stripes". Stripes befriends the other farmyard animals, including Saanen goat Franny and Shetland pony Tucker. One day, he becomes convinced that he is destined for the nearby racetrack, the Kentucky Open, after watching a race, not realizing that he is a zebra and is not qualified to race.
In 1969, Denver housewife and mother Penny Chenery (Diane Lane) agrees to take over her ailing father, Christopher Chenery's Meadow Stables in Doswell, Virginia, despite her lack of horse-racing knowledge. With the help of veteran trainer Lucien Laurin (Malkovich), Chenery navigates the male-dominated business, ultimately fostering the first Triple Crown winner in 25 years and one of the greatest racehorses of all time.
Bookie Duke Bradley (Clark Gable) stops the bank from taking the stud of Grandpa Clayton (Lionel Barrymore). Carol Clayton (Jean Harlow) calls from England that she is going to marry the wealthy Hartley Madison (Walter Pidgeon). Duke tells her father, Frank Clayton (Jonathan Hale), and Grandpa. Broke, Frank gives Duke the deed to the family farm to pay his gambling debts. At the races, Duke takes bets and meets Hartley and Carol. Duke greets Fritzi (Una Merkel) with a kiss. During a race, Frank collapses and dies.
Richard Briand-Charmery est connu sur tous les champs de courses comme « le Commandant ». À l'hippodrome de Longchamp avec Charly, un garçon d'écurie, il escroque ceux auxquels il vend des tuyaux. Un boucher, un patron de boîte de nuit, Arthur son ami... puis le restaurateur Gaspard Ripeux. Les jours de vaches maigres, il va déjeuner chez sa sœur Thérèse, subissant stoïquement les sarcasmes de son beau-frère Hubert, riche industriel.
Hugo Z. Hackenbush (Groucho Marx) is a veterinarian who is hired as chief of staff for the Standish Sanitarium, owned by Judy Standish (Maureen O'Sullivan), at the insistence of her most important patient, the rich Mrs. Upjohn, (Margaret Dumont), who insists on being treated only by Dr. Hackenbush. The Sanitarium has fallen on hard times, and banker J.D. Morgan (Douglas Dumbrille) is attempting to gain control of it. Judy hopes that Mrs. Upjohn will make a large donation and stop that from happening.
After failing a drug test in France, young jockey Christophe moves to Macau, where he becomes involved in the city's fast paced racing world. However, his luck seems to be running out when his trainer asks him to lose a race. With the help of beautiful Pamsy, he must find a way to avoid antagonizing the Chinese mafia.
Bill Grant, un représentant, se fait passer pour un homme riche auprès de Norma Rickson. Lorsqu'il la rencontre à nouveau sur un champ de courses, il prétend même être propriétaire de "The Phantom", un des chevaux. Cela va entraîner un certain ombre de péripéties, aux termes desquels Norma finalement décidera que la vie avec lui ne devrait pas être ennuyeuse.
Seo Ju-hee is a horse jockey who dreams of winning the Grand Prix championship. One day, she suffers an accident during a horse race and her beloved horse is put down and she injures her arm. She falls into depression and quits horse racing and decides to go to Jeju for a vacation. There, she meets Woo-suk, a fellow horse jockey who has previously won the championship. They fall in love and he helps and encourages her to make a comeback at the Grand Prix Championship.