A low-level marijuana dealer named David Clark (Jason Sudeikis) who lives in Denver is robbed of his money and stash, some of which he owes to his wealthy drug lord supplier Brad Gurdlinger (Ed Helms). After David is brought to him, Gurdlinger forces David to smuggle marijuana from Mexico as a solution to clear his debt. Realizing that one man attempting to get through customs is too suspicious, he hires a middle-aged stripper neighbor stage-named Rose (Jennifer Aniston), a runaway and petty thief named Casey (Emma Roberts), and his 18-year-old neighbor Kenny (Will Poulter), to pose as a bogus family called the "Millers". When the Millers reach the compound, they find out that the amount of marijuana they were picking up is not "a smidge" as Gurdlinger had informed them, but actually two tons. Because of the extra load of the marijuana on the RV, one of the radiator hoses breaks while going up a steep incline. A family they had encountered at the border, the Fitzgeralds, consisting of Don (Nick Offerman), Edith (Kathryn Hahn), and Melissa (Molly Quinn), catch up to them and tow the Millers' RV to a repair shop. On the trip to the shop, David learns that Don Fitzgerald is a DEA agent after finding his badge and gun in the glove compartment.
The once-successful steel mills of Sheffield, South Yorkshire, have shut down and most of the employees have been laid off. Former steel workers Gary "Gaz" Schofield and Dave Horsefall have resorted to stealing scrap metal from the abandoned mills to sell. Gaz is facing trouble from his former wife, Mandy and her boyfriend Barry over child support payments that he's failed to make since losing his job. Gaz's son, Nathan, loves his father but wishes they could do more "normal stuff" in their time together.
Anthony "Tony" Manero (John Travolta) is a 19-year-old Italian American man from the Bay Ridge neighborhood of Brooklyn in New York City. Tony lives with his parents (Val Bisoglio and Julie Bovasso), and works at a dead-end job in a small hardware store. The stagnant monotony of his life is temporarily dispelled every Saturday night when Tony is "king of the dance floor" at 2001 Odyssey, a local disco club. Tony has four close friends: Joey (Joseph Cali); Double J (Paul Pape); Gus (Bruce Ornstein); and the diminutive Bobby C. (Barry Miller). A fringe member of this group of friends is Annette (Donna Pescow), a neighborhood girl who longs for a more permanent physical relationship with Tony.
Mike (Tatum) has big plans for a business of his own but pays his bills through a series of odd jobs, most notably performing as the star stripper at Xquisite Strip Club in Tampa, a club owned by Dallas (McConaughey), who has dreams of creating an "empire" of strip clubs.
The Salesman steps out of the elevator and walks onto a penthouse balcony where The Customer, wearing a beautiful red dress, looks out over Basin City. He offers her a cigarette and says that she looks like someone who is tired of running and that he will save her. She smiles to him, the two share a kiss and he shoots her; she dies in his arms. He says he will never know what she was running from but that he’ll cash her check in the morning.
Three years after abandoning his life as a stripper, Mike (Channing Tatum) is now running his own furniture business. He receives a call from Tarzan (Kevin Nash) who informs Mike that Dallas is "gone". Believing that his former boss has died, Mike drives to a hotel only to find that his friends, the remaining Kings of Tampa, are enjoying themselves at a pool party. After revealing that Dallas has bailed on them to start a new show in Macau, the Kings let Mike in on their plan: to end their careers on a high note by traveling to Myrtle Beach for a stripping convention. Later, while trying to work, Mike overhears a song he used to strip to and dances. Reinvigorated, Mike decides to join them on their trip.
In the opening scene, twenty-four-year-old Alice Ayres (Natalie Portman) and Dan Woolf (Jude Law) see each other for the first time from opposite sides of a street as they are walking toward each other among many other rush hour pedestrians. Alice is a young American stripper who just arrived in London, and Dan is an unsuccessful British author who is on his way to work where he writes obituaries for a newspaper. Alice looks in the wrong direction as she crosses the street and is hit by a taxi cab right in front of Dan's eyes. After he rushes to her side she smiles to him and says, "Hello, stranger." He takes her to the hospital where Alice is treated and released. Afterward, on the way to his office, they stop by Postman's Park, the same park that he and his father visited after his mother's death. Pausing in front of the office before he leaves her and goes to work, he reminds her that traffic in England tends to come on from the right, and on impulse, he asks her for her name. They soon become lovers.
The film revolves around former FBI secretary Erin Grant, who loses custody of her young daughter Angela to her ex-husband Darrell. In order to afford an appeal, Erin becomes a stripper at the Eager Beaver, a Miami strip club. A Congressman named David Dilbeck visits the club and immediately begins to adore Erin. Aware of Dilbeck's embarrassing indulgences, another Eager Beaver patron approaches Erin with a plan to manipulate the Congressman to settle the custody dispute in Erin's favor. However, Dilbeck has powerful business connections who want to ensure he remains in office. Consequently, those who can embarrass him in an election are murdered. Meanwhile, Erin retrieves her daughter from her negligent husband.
Adrien works in an advertising agency in the day and at night he becomes the queen of a gay bar, run by her best friend, the seductive Eva. When Alexandre Agut, a major client of Adrien, wants to get to know him, he asks Eva to pose as his wife. Everything gets carried away when Alexander falls in love with her.
Two brothers, Seth and Richard "Richie" Gecko, having just robbed a bank, stop at a liquor store to pick up a map. When the arrival of Texas Ranger Earl McGraw threatens their getaway, they kill him and the cashier, burning down the store in the process. During the gunfight, Richie is shot in the hand. Fleeing a combined force of FBI and local police, they head towards Mexico where a contact has arranged a safe-house for them. Along the way they stop at a motel and unload a bank teller whom they are holding hostage. While Seth goes out to "sight see" checking on the border and to buy fast food burgers, Richie brutally rapes and murders the teller. Seth, who pictures himself as a professional thief, becomes furious over Richie's sadistic behavior.
Nomi Malone is a young drifter who hitchhikes to Las Vegas hoping to make it as a showgirl. After being cheated of her money by her driver, Nomi meets Molly Abrams, a seamstress and costume designer who takes her in as a roommate. Molly invites Nomi backstage at Goddess, the Stardust Casino show where she works, to meet Cristal Connors, the diva star of the topless dance revue. When Nomi tells Cristal she dances at Cheetah's Topless Club, Cristal derisively tells her that what she does is akin to prostitution. When Nomi is too upset to go to work that night, Molly takes her dancing at The Crave Club. After getting into a fight with James, a bouncer at the club, Nomi is arrested. James bails her out of jail, but she pays him little notice.
Determined to make her young, blonde, and beautiful daughter June a vaudeville headliner, willful, resourceful, domineering stage mother Rose Hovick will stop at nothing to achieve her goal. She drags the girl and her shy, awkward, and decidedly less-talented older sister Louise around the country in an effort to get them noticed, and with the assistance of agent Herbie Sommers, she manages to secure them bookings on the prestigious Orpheum Circuit.
Set in the poorer Naples of 1953, Adelina (Loren) supports her unemployed husband Carmine (Mastroianni) and child by selling black market cigarettes. When she doesn't pay a fine, her furniture is to be repossessed. However her neighbors assist her by hiding the furniture. A lawyer who lives in the neighborhood advises Carmine that as the fine and furniture is in Adelina's name, she will be imprisoned. However, Italian law stipulates that women cannot be imprisoned when pregnant or within six months after a pregnancy. As a result Adelina schemes to purposely stay pregnant. After seven children, Carmine is seriously exhausted and Adelina must make the choice of being impregnated by their mutual friend Pasquale (Aldo Giuffrè) or be incarcerated.
Jake Scully (Craig Wasson) is a struggling actor who has lost his role as a vampire in a low-budget horror movie after his claustrophobia thwarts shooting. He returns home to discover his girlfriend cheating on him, so Scully is left without a place to stay.
Lucía (Paz Vega), a waitress, is talking on the phone with her depressed writer boyfriend Lorenzo (Tristán Ulloa) after they had a nasty argument, where-after she walked out. Since he's been in a 'funk' for a while, she's worried, and goes home to console him. Finding an empty apartment, Lucía is frantic. She receives a phone call from the police while finding a suicide note, and is so afraid of bad news that she hangs up, assuming the worst. They call back, but she ignores the ringing phone, packs a bag, and flees. Looking for a new beginning, Lucía travels to the mysterious Balearic Islands that Lorenzo had always talked of, but had recently been very negative about.