The film is non-linear, framed by scenes of Nixon listening to his secret recordings towards the end of his presidency as the Watergate crisis intensifies. As such, it covers all aspects of Nixon's life as a composite of actual events, usually in the form of memories triggered by the recordings or newsreel-style summaries. It depicts his childhood in Whittier, California as well as his growth as a young man, football fan and player, and suitor to his eventual wife, Pat Ryan. It explores most of the important events of his presidency, including his downfall due to abuse of executive power in the White House.
The governor of an unnamed western state, Hubert "Happy" Hopper (Guy Kibbee), has to pick a replacement for recently deceased U.S. Senator Sam Foley. His corrupt political boss, Jim Taylor (Edward Arnold), pressures Hopper to choose his handpicked stooge, while popular committees want a reformer, Henry Hill. The governor's children want him to select Jefferson Smith (James Stewart), the head of the Boy Rangers. Unable to make up his mind between Taylor's stooge and the reformer, Hopper decides to flip a coin. When it lands on edge – and next to a newspaper story on one of Smith's accomplishments – he chooses Smith, calculating that his wholesome image will please the people while his naïveté will make him easy to manipulate.
On the morning of December 21, 1970, actor-singer Elvis Presley shows up to the White House and requests for an urgent meeting with President Richard Nixon, to swear him in as an undercover agent in the Bureau of Narcotics and Dangerous Drugs.
A U.S. Army librarian, Corporal Joe Bauers (Luke Wilson), and a prostitute, Rita (Maya Rudolph), are selected for a suspended animation experiment on grounds of 'average' appearance, intelligence, behavior, etc. Rita's pimp "Upgrayedd" (Brad Jordan) has been bribed to allow her to take part. The experiment is forgotten when the officer in charge (Michael McCafferty) is arrested for having started his own prostitution ring under Upgrayedd's tutelage. Five hundred years later, Joe and Rita's suspension chambers are unearthed by the collapse of a mountain-sized garbage pile, and Joe's suspension chamber breaks through the wall of Frito Pendejo's (Dax Shepard) apartment, whose occupant expels him.
L'agent du FBI Douglas Ripper est contacté par le shérif de Bornsville, qui lui annonce le vol du cercueil de Pamela Rose. Ripper pense alors pouvoir ainsi reprendre contact avec son ancien coéquipier Richard Bullit, à la retraite et contre lequel il s'était brouillé suite à une histoire de femme (la petite amie de Bullit quitte celui-ci pour Ripper).
The film begins with Bobby finding a winning lottery ticket but Mike insists that it be returned to the rightful owner. Mike then invites people to the house to prove they are the owner but none are able to answer correctly what the original wrote on the back of the ticket. A local newscaster hears the story and Mike agrees to an interview in hopes of finding the original owner.
Samantha MacKenzie (Katie Holmes) is the daughter of United States president John MacKenzie (Michael Keaton). She has been in the public eye her whole life. Having to deal with lack of privacy and public scrutiny for the most ridiculous things. She has recently spent a sheltered existence in the White House with her parents, but her father is usually too busy to look after her. Accompanied by Secret Service agents everywhere she goes, including the ladies room, Samantha finally believes she has the chance to break out of her cocoon when she is given the opportunity to attend college in California.
Duncan Fletcher (Will Friedle) is an average teenager in search of a date to his school's spring dance. At the mall with his friends, he meets a girl named Hallie (Elisabeth Harnois) who just happens to be the daughter of the President of the United States, George Richmond (Dabney Coleman). Duncan, not realizing this, asks her to his school's dance. She accepts and gives him her address (1600 Pennsylvania Avenue) and he replies by telling her he will pick her up at 7:00.
Following the events in Category 6: Day of Destruction, the superstorm that hit Chicago is continuing to grow in size and strength, with tornadoes hitting Paris and destroying the Eiffel Tower. Judith Carr (Gina Gershon), the new head of FEMA struggles to coordinate efforts to prepare for the aftermath of the storm and provide aid to ravaged areas. She calls in her former college lover, Dr. Ross Duffy (Cameron Daddo), and her father Senator Ryan Carr (Robert Wagner) to help her try to determine what is causing the storms and how to deal with the political issues. Tommy Tornado (Randy Quaid), who survived his seeming death in the previous film, returns to aid in tracking the storm in the United States, assisted by scientist Faith Clavell (Shannen Doherty). Similar storms are developing around the country and an interaction between urban heat islands and "falling chunks of mesosphere" fuels the storms making them more powerful. Hurricane Eduardo strikes toward Florida while the Category 6 storm hits Buffalo and heads towards New York City.
The first female U.S. President, Sally Sheridan, (Mimi Kuzyk) is killed by a sniper during her Veterans Day speech. Her assassin narrowly escapes after a shoot out involving a shadowy figure named La Mangouste (Val Kilmer) or "The Mongoose". Three months later in West Virginia, an elderly couple discover a young man (Stephen Dorff) who lies wounded in a tree and still in his parachute. He cannot remember his past and the only clue to his identity is a numerical tattoo on his chest, "XIII".
When a terrorist surfaces, the Chairman of the Joint Chiefs of Staff, General James Metzger (Nick Mancuso) urges President Mark Hayden (Lloyd Bochner) for a military response. However, the President prefers to try negotiating. So, the General takes the President hostage and launches an offensive of his own. The first female Vice President Elizabeth Lane (Joan Van Ark) is the only one who can do something about it and must fight mutineers in the White House to rescue him.