De retour en Allemagne, Beckmann découvre que, pendant qu'il était prisonnier en Sibérie, sa femme est avec un autre homme et son fils est mort. Il cherche désespérément un seul moyen de s'en sortir, parce qu'il "n'en peut plus". Alors qu'il marche le long de l'Elbe, il rencontre Anna Gehrke, qui "n'en veut plus". Tous deux racontent leurs vies.
Victoria is a Spanish girl who moved to Berlin three months ago, works in a cafe for a meager wage, does not speak German and does not know anybody in the new city. Leaving a club at around 4 o'clock in the morning after a night of dancing and drinking, she meets four young men who are denied entry to the club. They are "Sonne" (sun), "Boxer", "Blinker" (turn signal), and "Fuss" (foot). The men invite her to take a walk through the city and she agrees. After stealing some alcohol from an all night shop, they all get on the roof of an apartment building where they drink and smoke marijuana together, while Boxer reveals that he spent time in jail for hurting someone.
The film documents how Ry Cooder, long-time friend of Wenders, brought together the ensemble of legendary Cuban musicians to record an album (also called Buena Vista Social Club) and to perform two times with a full line-up: in April 1998 in Amsterdam (two nights) and the 1st of July 1998 in the United States (at the Carnegie Hall, New York City). Although they are geographically close, travel between Cuba and the United States is restricted due to the political tension between the two countries, so many of the artists were travelling there for the first time. The film shows their reactions to this experience, as well as including footage of the resultant sell-out concert. It also includes interviews with each of the main performers.
High school teacher Rainer Wenger is forced to teach a class on autocracy, despite being an anarchist. When his students, third generation after the Second World War, do not believe that a dictatorship could be established in modern Germany, he starts an experiment to demonstrate how easily the masses can be manipulated. He begins by demanding that all students address him as "Herr Wenger", as opposed to Rainer, and places students with poor grades beside students with good grades—purportedly so they can learn from one another and become better as a whole. When speaking, they must stand and give short, direct answers. Wenger shows his students the effect of marching together in the same rhythm, motivating them by suggesting that they could really annoy the anarchy class, which is below them. Wenger suggests a uniform, to remove class distinction and further unite the group. Mona argues it will remove individuality, as well. Karo shows up to class without the uniform and is ostracised. The students decide they need a name, deciding on "Die Welle" (The Wave). Karo suggests another name, which ends up with one single vote cast by herself.
At the beginning of his summer holiday, a somewhat naive trainee teacher Daniel (Moritz Bleibtreu) buys a ring from a stall run by a neighbor, the aspiring artist and street vendor Juli (in German, "Juli" would be not only the month July but also a common nickname for someone named "Julia"; Christiane Paul). The ring bears a Mayan sun symbol, which, according to Juli, has the power to lead him to the woman of his dreams, whom he will recognise by a similar sun symbol. As Juli has the ring's counterpart, and as she is in love with him, she invites Daniel to a party that evening, hoping that they will meet.
Berlin: Symphony of a Metropolis is largely an avant-garde film, and does not have a story or a plot. However, the events of the film are arranged to simulate the passage of a single day (simulated from an assemblage of film shot over the period of one year). Shots and scenes are cut together based on relationships of image, motion, point of view, and thematic content. At times, a sort of non-narrative commentary can be implied, as in edits that juxtapose workers entering a factory with cattle being beaten and driven into a corral.
The film presents extracts from some of the most noted dance pieces by Pina Bausch in the Tanztheater ("dance theater") style of which Bausch was a leading exponent. The extracts are from four pieces: Le sacre du printemps (The Rite of Spring), Café Müller, Kontakthof, and Vollmond. These are complemented with interviews and further dance choreographies, which were shot in and around Wuppertal, Germany; the film includes scenes showing the Wuppertal Schwebebahn, an elevated railway, and some dance sequences take place inside its carriages.
Josef K. (Anthony Perkins) is sleeping in his bedroom, in an apartment he shares with other lodgers. He is awakened when a man in a suit opens his bedroom door. Josef assumes the glib man is a policeman, but the intruder does not identify himself and ignores Josef's demand to produce police ID. Several detectives enter and tell Josef he is under open arrest. In another room Josef K. sees three co-workers from his place of employment; they are there to provide evidence regarding some unstated crime. The police refuse to inform Josef K. of his misdeeds, or if he is even being charged with a crime, and they do not take him into custody.
Solek (a nickname for Solomon, also called "Solly") and his family live in Nazi Germany. On the eve of Solek's bar mitzvah, Kristallnacht occurs. He escapes, naked, then hiding in a barrel. At night, he calls his acquaintance to bring him clothes from his house. She refuses, but throws him a leather jacket with a swastika band on its arm. He comes back home. His family is together at home, but his sister is killed by Nazis. The father, who was born in Łódź, Poland, decides to go back there.
In wartime Munich, Sophie Scholl joins members of the White Rose student organization, including Sophie's brother Hans, who are preparing copies of their sixth leaflet. They have mimeographed more than they can distribute through the mail. Hans proposes distributing the extras at university the next day; despite Willi arguing that the risks are unacceptable, Hans says that he will take full responsibility, and Sophie volunteers to assist.
The story culminates in a pilgrimage to Mount Fuji in the midst of the cherry blossom season, a celebration of beauty, impermanence, and new beginnings.
In the Expressionistic frame story, in which human lives are each represented by a candle, Death grants a woman three chances to save her lover, if love can triumph over death. The three stories within the story each occur in a setting that is nominally historic, but really in the realm of fantasy: an adventure tale with a Persian setting out of the Arabian Nights, a Renaissance Venetian romance, and a largely comic story set in China.