The film focuses on the descendants of the DeWolf family, a prominent slave trading family from Rhode Island from 1769 to 1820, and the legacy of the slave trade in the North of the United States. The film follows ten family members as they retrace the triangle trade starting at Linden Place in Bristol, Rhode Island, the hometown of the DeWolfs. The family has been prominent in local businesses and banking, as academics, in the local Episcopal and other institutions, and organizing the Bristol Fourth of July Parade. The film goes with the family to Ghana, where the slaves were purchased and where they meet with current residents, and to Cuba, where James DeWolf owned three sugar and coffee plantations in the 19th century.
In 1841, Solomon Northup is a free African-American man working as a violinist, who lives with his wife, Anne Hampton, and two children, Margaret and Alonzo, in Saratoga Springs, New York. Two men, Brown and Hamilton, offer him a two-week job as a musician if he will travel to Washington, D.C., with them. Once there, they drug Northup and deliver him to a slave pen owned by James Burch.
The story takes place in Cuba in 1850, in the era of the Black slave trade. In a sugar cane plantation, Captain Jorge (Ramón Gay) and his wife, Beatriz (Rosa Elena Durgel) live happily: are expecting a child, and their slaves live quiet and at peace with them. But one night, as the full moon appears, the sound of drums rises in the air. Yambao (Ninón Sevilla), the granddaughter of a witch supposed murdered 15 years ago named Caridad (Fedora Capdevila), has reappeared. The plantation slaves begin to fear. Her grandmother was killed by them due to black magic and curses that fell on the plantation thanks to her. Yambao's arrival coincides with a new outbreak of black vomit, not appearing on the plantation for decades, and all attributed the situation to the black magic of the girl. Yambao it's not really bad, but Caridad, who actually survived her assassination attempt, is the one who fills her heart with hatred and revenge. Jorge stays out of the traditions and customs of his slaves, but when he discovers that these want to sacrifice the girl, decides to intervene. Jorge saves Yambao, who swears eternal gratitude. But the girl starts to fall for him. Her grandmother decided to take advantage of this feeling from her revenge. Yambao decides to perform a magic ritual of Santeria over Jorge to make him love her. Her magic spell coincides with the contagion of Jorge of the epidemic plague. The doctors did not give hopes to Jorge. Yambao decides to intervene and offered her to cure him in gratitude for saving her life. The contact with Jorge, rooted even more her feelings. When Jorge manages to save himself from danger, he begins to feel the desire to be near of Yambao, which suggests that the spell has worked. For several weeks Jorge is delivered with passion for Yambao, forgetting his wife, his plantation and all his duties. However, when Jorge is informed that his wife is about to give birth, he runs to her side, and when his child born, his mind is clear and decides to return to his family. Yambao seeks revenge, and advised by Caridad decides to kill the wife and the son of Jorge. Fortunately, when about to consummate the crime, her grandmother, Caridad, is discovered by the foreman of the plantation, who kills her with a machete. Yambao flees in horror, promising not to cause any damage. The witch Caridad is the subject of a funeral ceremony with exotic rituals. At the end of the ritual, Yambao decides to end her own life by jumping off a cliff, to the astonishment of Jorge.
[On-screen text: "Salem, Mass. 1800"] Fur trapper Jason Starbuck (Jeff Chandler) arrives in Salem. A general store owner challenges him to a horse race, but his rider's fiancee, Roxana Reil, gives a helpful tip to Starbuck on how to win the race.