Told from Igor's perspective, it shows the troubled young assistant's dark origins, his redemptive friendship with the young medical student Victor Frankenstein, and become eyewitnesses to the emergence of how Frankenstein became the man who created the legend we know today. The two's experiments eventually get them into trouble with the authorities and they are near to becoming fugitives as they complete their goals to use science to create life, with Frankenstein's ultimate endgame of creating a man.
Nuclear apocalyptic survivor Ann Burden ekes out an agrarian life on her family's valley farmstead, sheltered from radioactive contaminants by rocky hillsides, favorable weather patterns, and an abundant ground-fed water supply. One day Ann encounters fellow survivor John Loomis, a highly-skilled engineer, who, aided by medicines and a radiation suit, has traveled from a distant military bunker to the safe confines of Burden's valley. Loomis bathes in contaminated water, and immediately sickens, but is nursed back to health by Ann, who welcomes him into her farmhouse.
In the 2030s, the crew of Ares III, a manned mission to Mars, has established a temporary artificial habitat, called the Hab, on Mars, where they are to stay for two months and depart back to Earth in their orbital probe. Eighteen days into the Mars mission, however, a massive Martian storm hits the base and the crew is forced to abandon the planet and launch themselves because of the danger that their escape vehicle will collapse and leave them stranded. While evacuating, astronaut Mark Watney is lost and presumed dead as his biomonitor is damaged. With the lives of her crew at stake, mission commander Melissa Lewis is forced to leave the planet, leaving Watney behind.
A race of extraterrestrials called Mimics has taken over continental Europe. In England, General Brigham, head of humanity's United Defense Force, orders Major William Cage, a public affairs officer with no combat experience, to cover the next day's amphibious assault in France. Cage objects to the dangerous assignment and threatens to blackmail Brigham to avoid it. Brigham has Cage arrested; Cage is knocked out trying to escape. He wakes in handcuffs at a forward operating base at Heathrow Airport and discovers he has been demoted to private, charged with desertion, and assigned to a combat squad named "J" squad under the command of Master Sergeant Farell.
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The owner of the 20th Century Motor Company has died and his children have taken over, with a new plan to operate the company: that everyone work as hard as he can, but that salaries be "based on need". A lab engineer named John Galt objects and announces, "I'll stop the motor of the world."
Ten years after the worldwide pandemic of the deadly ALZ-113 virus (known as the Simian Flu), human civilization is completely destroyed following martial law, civil unrest and the economic collapse of every country in the world. Over 90% of the human population has died in the pandemic, while apes with genetically enhanced intelligence have started to build a civilization of their own.
In 1795, Dr. Victor Frankenstein (Aden Young) creates a monster (Aaron Eckhart), a soulless creature patched together from corpses, and then rejects it, disgusted with what he's made. In a fit of rage, the creature kills Victor's wife Elizabeth (Virginie Le Brun) and Victor chases it to the Arctic to get revenge, but succumbs to the weather. The creature buries his creator in the Frankenstein family crypt and is then attacked by demons before being rescued by the gargoyles Ophir (Mahesh Jadu) and Keziah (Caitlin Stasey), who bring it before the gargoyle queen Leonore (Miranda Otto) and their commander Gideon (Jai Courtney). Leonore explains that they were created by the Archangel Michael to battle demons on Earth and protect humanity. They name the creature "Adam" and invite him to join them, but he declines and departs after being given heavy, baton-like weapons to protect him, as more demons will come after him. The weapons allow him to "descend" demons (destroying their bodies and trapping their souls in Hell) as they have the symbol of the Gargoyle Order carved on them.
In 1895, a young immigrant couple is refused entry into Manhattan because they have consumption. When their infant son is not allowed entry to the country without them, the couple place him in a model sailboat named "City of Justice," in which the baby floats to the New York City shoreline. In 1916, the baby boy has grown up to become Peter Lake (Colin Farrell), a thief raised by a supernatural demon posing as the gangster Pearly Soames (Russell Crowe). Peter is marked for death when he decides to leave Pearly's gang. In a confrontation, he is rescued by a mysterious (winged at times) white horse, his guardian angel.
The story is set in an alternate reality America circa 1985 under the authoritarian control of President Fremont. It makes liberal references to the collected works of Philip K. Dick.
A 16-year-old boy wakes up inside an underground service elevator with no memory of his identity. A group of male youths greet him in a large grassy area called the Glade that is enclosed by tall, stone walls. Every month, a new boy and supplies arrive in the elevator. The boys, who call themselves Gladers, have formed a rudimentary society with each assuming specialized tasks. Alby, their leader and the first to arrive in the Glade, says every boy eventually recalls his name, but none remember their past. The boy learns that a vast Maze surrounding the Glade may provide the only way out. During the day, designated Runners search the Maze for an escape route, returning before nightfall when the entrance closes. No one has ever survived a night inside the Maze.
Velma gets a call from Cuthbert Crawley, a lawyer for Velma's family who tells her that she's inherited her great uncle's property and castle in Transylvania. Velma turns the offer down, replying she wants nothing to do with her uncle, puzzling the gang. Mr. Crawley understands, revealing the curse over the estate. He says that if anyone gets too close to the Baron legacy, then what they love the most will be destroyed. As they head outside, Fred hears a noise from the Mystery Machine, then it explodes and a mysterious character with a mask appears. Crawley reveals that it's the ghost of the Baron, Velma's old ancestor. The remains of the machine explode again, with words saying stay away from Transylvania, but Fred declares that is where they're going to find the person responsible for destroying the Mystery Machine, saying this time "it's personal".
The human race has been taken over by small parasitic aliens called "Souls". The Souls travel to distant planets inserting themselves individually into a host body of that planet's dominant species. They are able to access the host's memories, and occupied hosts are identifiable by silver rings that form in the hosts' eyes.
In the future, humanity is preparing to launch an attack on the homeworld of an alien race called the Formics who had attacked Earth and killed millions. Over the course of fifty years, gifted children are trained by the International Fleet to become commanders of a new fleet for this counter-attack.
Robin Wright plays a fictional version of herself, an aging actress with a reputation for being fickle and unreliable, so much so that nobody is willing to offer her roles. Her son, Aaron, suffers from Usher syndrome that is slowly destroying his sight and hearing. With the help of Dr. Barker (Paul Giamatti), Robin is barely able to stave off the worst effects of her son's decline. Robin agrees to sell the film rights to her digital image to Miramount Studios (a portmanteau of Miramax and Paramount) in exchange for a hefty sum and the promise to never act again. After her body is digitally scanned, the studio will be able to make films starring her, using only computer-generated characters.
In the 2040s, a Martian research base, Tantalus Base outpost, is created. The eight person crew, who have been stationed there for six months, are only nineteen hours from the completion of their research mission. The spacecraft Aurora is inbound from Earth and will collect the team by lander from a prearranged site. Mars scientist Marko Petrović has found samples that may point to life on the planet. Without revealing his discovery, he devises a ruse for one last sojourn on the surface. Crewmate Richard Harrington drives Petrović in a solar powered rover to the spot where he had found the sample. After he obtains soil with the biological agent present, a fissure swallows Petrović.