After Andy Flynn destroyed the original Sharktopus (a half-shark half-octopus creature), its various pieces floated back out into the ocean. However, among the scattered anatomy was an egg sack and marine biologist Lorena finds herself the ward of the creature's sole offspring which she begins raising at her uncle's aquarium to mixed success. Meanwhile, Dr. Rico Symes is hard at work on his own biological weapon. After harvesting a pterodactyl's DNA, he used the DNA from a barracuda to fill in the gaps, creating a monster that can terrorize land, sea, and air. Things are looking pretty good during the initial test flight until the creature is hijacked by a rogue engineer, looking to sell it the highest bidder. He probably would have gotten away with it if he didn't spill his coffee all over his console, but now the Pteracuda is free to rampage the coast in search of food.
Le Sharktopus est de retour sur ses meurtres contre l'humanité dans la ville. Entre-temps, une scientifique crée un hybride mi-loup mi-orque, le Whalewolf, qui va aussi commettre des meurtres dans la ville. Il y aura une lutte sans merci entre les deux hybrides.
In September 1942, Captain Yamagami (Susumu Kurobe) is ordered to rendezvous the Yamato with the Combined Fleet that is gathering at the Truk Islands (aka Chuuk Islands) in Micronesia, a key strategic point in the South Pacific. With beautiful clear blue skies above and surrounded by coral reefs below, this South Seas paradise became a strong base for the Combined Fleet and the front lines of the naval war; a place where many fierce battles were fought. Decades later, the sea bed surrounding the Truk Islands is still littered with the remains of more than 60 warships and airplanes.
A small town, desperate to recover from hard economic times, is under threat when the voracious snakehead fish mutate, surviving previous chemical attacks. The fish transform from pests to predators when human growth hormones are dumped into the local lake in the hopes of reviving the local fishing industry. Thriving on the hormones, the Snakehead fish grow to monstrous proportions, devouring everything within reach. Capable of moving and eating on land, they are forced to leave the now barren lake in a desperate search for food - animal, vegetable or human. In a race against time, the local Sheriff and biologist Lori Dale, try to save the Sheriff's teenage daughter and her friends, along with the town itself, from being eaten alive.
The film reduced Wells' tale to an "Ecology Strikes Back" scenario, common in science fiction movies at the time. The "food" mysteriously bubbles up from the ground on a remote island somewhere in British Columbia. Mr. and Mrs. Skinner (John McLiam and Ida Lupino) consider it a gift from God, and feed it to their chickens, which grow larger than humans as a result. Rats, wasps, and grub worms also consume the substance, and the island becomes infested with giant vermin. One night, a swarm of giant rats kill Mr. Skinner after his car breaks down in the forest.
In the 23rd century, Earth has become a space-faring federation. While colonizing new planets, humans have encountered an insectoid species known as Arachnids or "Bugs", with their home being the distant world Klendathu. The bugs appear to be little more than killing machines, though there are suggestions that they were provoked by the intrusion of humans into their habitats.
On a planet inhabited by Arachnids, a squad of soldiers find themselves pinned down and surrounded on all sides by Arachnid forces—even with their new laser gun technology and assistance from psychic soldiers, the Arachnid assault overwhelms them. General Jack Shepherd (Ed Lauter) decides to make a last stand with four of his best soldiers to allow the majority of his surviving troops to escape. The plan works and the soldiers escape, including Sergeant Dede Rake (Brenda Strong), psychic Lieutenant Pavlov Dill (Lawrence Monoson), Private Jill Sandee (Sandrine Holt) and her lover Private Duff Horton (Jason-Shane Scott), and Private Lei Sahara (Colleen Porch). Despite reaching relative safety, the team is whittled down by deadly storms and arachnid ambushes—including the only member of the platoon with a radio, Corporal Thom Kobe (Brian Tee). Lieutenant Dill is unable to command his soldiers as he receives traumatic visions of utter annihilation. He takes his anger out on Private Sahara, who is revealed to have been psychic but lost reliable control of her psychic abilities during puberty.
Professor Scott Kinney is an American geologist monitoring a local volcano when the Supergator, a Phobosuchus recreated from fossilized, preserved DNA escapes from a secret bio-engineering research center/laboratory. Along the way, it eats thirteen people, including two lovers, three drunken teens, three models, two tourists and a fisherman. It also eats Alexandra Stevens and Ryan Houston.
A man with Neanderthal features and wearing pajamas stumbles through the Arizona desert, falls and dies. Dr. Matt Hastings (John Agar), a bright, handsome and sympathetic doctor from the small town of Desert Rock, is called to view the body. Asked to give an opinion as to cause of death, he finds himself perplexed. Surprised to learn the deceased was someone he knew – biological research scientist Eric Jacobs – Dr. Hastings suggests he be given permission to perform an autopsy to learn why the man's face is distorted beyond recognition. The sheriff refuses, judging an autopsy unnecessary as Jacobs' associate, Dr. Gerald Deemer (Leo G. Carroll), signed the death certificate and there is no indication of foul play.
On a Swiss mountain, one of three student climbers is killed, his head ripped from his body. Two sisters, a London mind-reading act, are traveling by train to Geneva when one of them, Anne Pilgrim (Janet Munro), faints as they pass the same mountain. Upon waking, she knows that there is something very wrong, so she decides they should get off at the very next stop, Trollenberg.
A newlywed deputy, Martin Gordon (Vic Savage), encounters an alien spacecraft that has crash landed in fictional Angel County in California. A large, hairy, slug-like, omnivorous monster emerges from the side of an impacted spaceship. A second one, still tethered inside, kills a forest ranger and the sheriff (Byrd Holland) when they independently enter the craft to investigate.
Mitch MacAfee (Jeff Morrow), a civil aeronautical engineer, while engaged in a radar test flight near the North Pole, spots an unidentified flying object. Three jet fighter aircraft are scrambled to pursue and identify the object but one aircraft goes missing. Officials are initially angry at MacAfee over the loss of a pilot and jet over what they believe to be a hoax.
In late 2000, an American military pathologist commands a reluctant Korean assistant to violate protocol by dumping over 200 bottles of formaldehyde down a drain leading into the Han River. Over the next few years, there are sightings of a strange amphibious creature in the waterway, and the fish in the Han River are dying off because of water pollution. A suicidal businessman, just before jumping off a bridge into the river, sees something dark moving under the surface of the water.
Captain Thorne Sherman and first mate Rook Griswold deliver supplies by boat to a group on a remote island. The group, consisting of scientist Marlowe Cragis, his research assistant Radford Baines, the scientist's daughter Ann, her recent fiancé Jerry Farrel, and a servant Mario, welcome the captain and his first mate, but subtly resist the visitors staying overnight, even though a hurricane approaches. Thorne goes with the group to their compound. Griswold stays with the boat, to come ashore later.
Jeff Philips is working a dead end job at a call center. One day, an old man arrives at his apartment to tell him he is the last descendent of H.P. Lovecraft and must guard a relic to keep it from being reunited; if the pieces of the relic are united while the stars are in alignment, the sunken city of R'lyeh will rise from the sea and the demonic creature Cthulhu will be released upon an unsuspecting world.