When protagonist Derek Washington (Hall) was just a child, he witnessed his father's murder. Because of this, he became very afraid of blood. However, when a sting operation to find a counterfeiter named Gustoff Slovak (Mel Novak) goes wrong, Derek is forced to face his fear: blood. The operation backfires, resulting in a massacre that leaves Derek's team wiped out. Derek reaches the shocking conclusion that Slovak is actually a vampire, and joins forces with a weapons expert named Master Kao (Gerald Okamura). Kao is the last in a long line of vampire hunters, and agrees to train Derek in this ancient art of vampire slaying. However, in order to defeat Slovak, Derek must become a vampire assassin.
After Baron Henry von Frankenstein creates a bride his monster, he decides to make arrangements for a lavish wedding at the Transylvania Astoria Hotel. Many monsters are invited to the wedding including Count Dracula and his son, Ron Chanley the Werewolf, the Mummy, Dr. Jekyll and Mr. Hyde, the Invisible Man and his family, and the Creature from the Black Lagoon. Once the wedding guests arrive, they terrify guests and staff. Frankenstein's assistant Igor is jealous of the monster and wants the bride for his own. So Igor plots to steal her which doesn't go according to plan when the bride ends up snatched up by a Pterodactyl and lands in the clutches of a giant gorilla named Modzoola.
Set in 17th-Century Japan, "Zen" is the chronicle of a young samurai, Master Mitzu Zen, who learns the secret way of killing vampires while learning about women and life in general. Master Zen (Kit DeZolt), a naive master who doesn't know anything about women and love, goes on a quest to find out the truth about his parents' sacred sword. While meeting people along the way, he ends up running into more than he bargained for when he starts encountering vampires.
Very little was released publicly regarding the plot of the remake and the extent to which it would be faithful to the original. It was expected that the central focus would be on three teenagers in a family of vampires traveling Route 66 in the late 1980s.
The plot line focuses on the Lassader family, headed by Joe and Carol, whose daughter Selena searches out Derek McGregor and his team to hunt and kill a vampire colony that is holding the family hostage by drinking the blood of their livestock, the source of their income. Accepting the offer, McGregor and his small team begin a bloody, terrifying journey to track and destroy the evil vampire brood, with the help of vampire specialist Xavier Burns.
Count Murnau, a wealthy eccentric from the Carpathian region wishes to buy a property in Hannover, Germany. The real estate agency sends Mr. Dohart, his best sales representative to close the deal, but Dohart never gets back. The real state agency sends the young and newlywed Hutter to take care of this matter, and he departs alone to Transylvania leaving his wife Ellen waiting for his return.
Klaha and Cecil are set to get married. However, their wedding must be postponed because Klaha is summoned from England to Romania on business. Klaha goes to Transylvania, and arrives at the Earl of Dracula's castle, where he is staying. The Earl seems welcoming, but Klaha has strange experiences while staying there. On his arrival, he notices a painting of the Earl's deceased wife, who looks very much like Cecil. 2 nights later, the Earl agrees to buy a house in England. That same night, after having a nightmare, Klaha wakes up to see a coffin leaving the grounds. While looking for the Earl, Klaha sees the painting again, but this time, the word "Cecil" is written under it. Too late does Klaha realise that the Earl is a vampire. He immediately leaves to try to catch up with him.
Gretchen (Sean Serino), a young woman, becomes desperate to contact her brother after his passing. She discovers an amulet that allows her to control the dead—which she uses to try and contact him. The amulet also allows results in the calling forth of a small army of zombies, comedically called "Post-Mortem Americans" in the film. This amulet is a sought after relic, pursued by two feuding vampires who have been at odds for millennia: Vellich (Andrew Divoff) and Sebed (Tom Savini). After encountering the vampires, Gretchen and her friends are joined by the vampire-hunter McCallister (Jason Carter), who had originally stolen the amulet from Vellich. McCallister helps Gretchen and her friends combat the villains, and the film ends with a final showdown between the protagonists and the vampires. The film was called a "vampire-zombie hybrid movie" by the Columbus Dispatch.