The rebels want the "Dutchman" (Peter Graves) to rob a train carrying $500,000 in gold on behalf of Victoriano Huerta to finance the Mexican Revolution. So the Dutchman enlists four other men, a strong man (Bud Spencer), an acrobat (Nino Castelnuovo), an explosives specialist (James Daly) and a samurai (Tetsuro Tamba), promising to reward each one a thousand dollars. Their first undertaking is to save the rebel leader from being executed.
Renowned gunman Richard Martin is traveling on a train, held up by Billy Kane, a former student of Martin's. Kane spares Martin, but only after shooting his hands. Years later, Martin meets an escaped convict, wrongly convicted for the train robbery. Martin trains his new student and both men seek out Billy Kane.
The young English nobleman Sir Thomas Fitzpatrick Phillip Moore (Terence Hill) arrives in the West following the wish of this late father who years earlier had to leave England due to an affair. The trouble led to a conflict with "Vicci Windsor". In the West, the young man joins up with his father's former pals, the stagecoach robbers Monkey (Dominic Barto), Holy Joe (Harry Carey Jr.) and Bull (Gregory Walcott).
After surviving his family being massacred, a young boy is taken in and raised by a preacher. Years later he comes face to face with the man that killed his family and he is tempted back into violence.
Nero portrays Tom Corbett, a prospector called back to his hometown by a family friend. Upon his arrival in the town, Tom finds it under the control of a powerful, corrupt family. With the help of his alcoholic brother, Tom sets out to challenge the family and free the town from their rule.
On the eve of his return to Spain from the New World, Diego de la Vega (Alain Delon) meets his old friend Miguel de la Serna (Marino Masé), who is about to take up the governorship of Nueva Aragón - after his uncle Don Fernando died of “malaria” in a malaria-free region.
Django is wounded and his wife is killed when the gold transport that he guards is attacked by the men of his ”friend” David Barry, who wants the gold to finance a political career.
When he returns home from war the Mexican general Juan Carrasco is killed by the lover of his wife Anna. The victim's children run away with their nanny but fifteen years later they come back for revenge. Anna and Tomas want to have them killed but their henchmen fail them. It turns out Anna is not the real mother of the dead general's children.
The president ends up dying from an assassin's bullet, but Willer's further quest for revenge is ultimately more successful. Spanish actress Maria Cuadra plays Lucreatia Garfield, the President's wife. In her role she portrays pretty much the role of Jackie Kennedy as a glamorous President's wife. Even in the assassination scene, Cuadra seems to emulate many of the same actions from Jackie Kennedy's last moments with John F. Kennedy in Dallas in 1963.
Bounty hunter John delivers four wanted criminals, all of them dead. When he checks out the new posters at the sheriff's office he recognises his half-brother Clint on one of them. John could never forget how Clint out of jealousy killed their mutual father and how he blamed the misdeed on John who instead of his brother spent 10 years in prison. Now Clint is good for 6000 dollars. John has no reservations to go after him because it was Clint who rendered John an outcast with no other chance left to make a living other than by becoming a bounty hunter. When John eventually gets to him, Clint is just fighting with his gang about a booty of 100.000 dollars.
Having massacred an Indian village, outlaw Duncan finds his men falling victim to a solitary rider, Navajo Joe. Joe saves three prostitutes who have overheard Duncan plot with Lynne, the town doctor, to steal a train full of money belonging to the bank. Joe steals the train back from Duncan's gang. He asks the townspeople of Esperanza to pay him to protect them from Duncan, making an offer of "I want a dollar a head from every man in this town for every bandit I kill". The townspeople reject him, as they "don't make bargains with Indians." Lynne's wife Honor persuades them otherwise. Joe sets a trap for Duncan but is caught and tortured; Lynne and Honor are killed. Rescued by an old man from the saloon, Joe again steals the train and eradicates Duncan's gang. There is then a showdown in an Indian cemetery, where Joe reclaims the pendant which Duncan stole from his wife when he murdered her. As Joe turns, Duncan shoots Joe with a hidden gun. Injured, Joe grabs a tomahawk and throws it, hitting Duncan square in the forehead. With Duncan dead, Joe sends his horse back to town, carrying the Bank's money.
American and Mexican outlaws rob a US Army gold transport. After the successful ambush the Americans attempt to keep the booty for themselves by planning to execute the Mexicans, though one of their number breaks free and kills several of their horses with a machete. The Mexicans dig their own grave and are shot, however their leader is badly wounded and survives being buried alive. He is rescued by a pair of Indians who treat his wounds in exchange for his addressing their people on what he has seen of the afterlife during the period he was "dead". They also give him golden bullets to use for his revenge. Pursuing the gang that killed his comrades, the Stranger finds shelter among locals but Templer, a saloon owner, Hagerman an Alderman who keeps his wife a prisoner in their home and Sorrow, the leader of a band of black garbed homosexuals hear about the gold and want it for themselves.