Danny O'Shea (Rick Moranis) has always lived in the shadow of his older brother, Kevin (Ed O'Neill), a Heisman Trophy winner and a local football hero. The brothers live in their hometown of Urbania, Ohio. Kevin coaches the local "Pee-Wee Cowboys" football team. Despite being the best player, Danny's tomboy daughter Becky (Shawna Waldron), nicknamed Icebox, is cut during try outs because she is a girl. Also cut are Becky's less-talented friends, Rasheed Hanon (who can't catch anything), Tad Simpson (who can't run) and Rudy Zolteck (who's overweight and quite flatuent). After being ridiculed by the other players who made the team, she convinces her dad to coach a new pee-wee team of their own.
The film opens with Shane Falco, a former star quarterback at The Ohio State University who choked in his final college game and failed to succeed in the pros, doing his job cleaning the bottoms of peoples' boats. While underwater, he finds a metal trophy football labeled "Shane Falco: All American" and pretends he is playing football again.
Lucas Bly (Haim) is an extremely intelligent and nerdy 14-year-old high school student. He soon becomes acquainted with Maggie (Green), an attractive older girl who had just moved to town. After meeting Lucas on one of his entomological quests, Maggie befriends him, spending time with him during the remainder of the summer until school begins. Lucas, who finds himself a frequent victim of bullying and teasing, has a protector of sorts, Cappie Roew (Sheen), a fellow student and football player; Cappie was once one of Lucas' tormentors, until Cappie contracted hepatitis and Lucas brought him his homework every day, ensuring that Cappie didn't fail and have to repeat a year of school. Even though Lucas deems it beneath her, Maggie becomes a cheerleader for the football team in order to get closer to Cappie, on whom she has a growing crush. Angered and offended by Maggie continuing to ignore him, Lucas begins to irritate Maggie, continuing to castigate her cheerleading as "superficial" and making the incorrect assumption that she will be his date to an upcoming school dance. Maggie complains to Lucas that she's interested in things besides just hanging out with him all the time, and Lucas' unrequited affection for her continues to upset him.
Minden, Illinois, is a former factory town with no money and a pathetic football team. Curtis Plummer, a down-and-out former football player is going nowhere, until he meets his niece Jasmine, the daughter of his no-good brother. Jasmine has worn her father's watch ever since he left five years ago, in the hopes that he will return. Her mother Claire asks Curtis to take care of Jasmine after school, because Claire has to work at the town diner. Curtis realizes Jasmine has a talent for throwing a football, which he nurtures into a passion for the game. He then persuades her to try out for the town's Pop Warner football team, the Minden Browns, because he thinks it would be good for her and the team. The team, including the coach, are against it, but her abilities gain her a spot on the team. However, the coach keeps her on the bench. In the fourth game, after much prodding from Curtis, the coach puts Jasmine in the game, and although they lose, everyone said they could have won if she had played from the beginning. Jasmine becomes the starting quarterback and the Minden Browns become a winning team.
Coach Dudley (Jack Holt) is a hard-driving college football coach, who strives to shape the character of his players, transforming them into real men. Unfortunately, the Coach's son, Bob (Richard Cromwell), who plays for him, hates sports and participates only because he is forced to do so. Bob lets his team down through cowardice and laziness and as a result is rejected by his father, his college sweetheart Dorothy (Joan Marsh), and his school. Bob joins a rival college team with the plan to defeat his father's team. In the end, Bob pulls himself together to win the Big Game, proving himself worthy of his father's name.
Set in 1951 in South Korea, the 4077th Mobile Army Surgical Hospital is assigned two replacements: Captains "Hawkeye" Pierce and "Duke" Forrest, who arrive in a stolen Jeep. They are insubordinate, womanizing, mischievous rule-breakers but they soon prove to be excellent combat surgeons. They immediately clash with their new tent mate Frank Burns, who is both a religious man and an inferior, stubborn, inept and incompetent surgeon who, when he causes mistakes, selfishly accuses anyone that is aside him. Hawkeye and Duke pressure Lt. Colonel Henry Blake, the unit CO, to have Burns removed from "their" tent. They also ask him to apply for a specialist thoracic surgeon to be assigned to the 4077th. Their wish is granted when Captain "Trapper" John McIntyre arrives at the 4077th.
In the last game of the American Football Federation between the Boston Rebels and the New York Dukes, Rebels quarterback Joe Kingman (Dwayne Johnson) scores a touchdown after ignoring an open wide receiver, Travis Sanders (Morris Chestnut). The next morning, an 8-year-old girl named Peyton Kelly (Madison Pettis) arrives on Kingman's doorstep saying that she is his biological daughter, and that his divorced wife sent her there to meet him. Kingman's agent, Stella Peck (Kyra Sedgwick), thinks this will be bad for his image and distracts him with the upcoming playoffs.
George Irving, the president of Upton college is in serious danger of losing his job. For the last twelve years Upton has lost the football match against Parsons college. The trustees of Upton insist that Irving must resign if Upton fails to win the upcoming football match. Joan Bennett, who is Irving's daughter, overhears the threat of the trustees and tells her friend Joe E. Brown, who is a star football player. Together they come up with a scheme to get some of the best football players around to sign up to play for Upton. Bennett completely changes her appearance to vamp the various men into thinking she will be interested in them if they attend Upton in the following season and play for the football team. One by one they all fall for the scheme and sign up for Upton. Irving, however, refuses to admit James Hall into the college because of his poor performance in academics. Because of the coach's insistence on needing him to win the game, Bennett helps Hall sign up under a fictitious name and credentials. All is well until Hall finds out about Bennett scheme and tells the rest of the team. Just before the game, the Upton team pretends to be drunk in order to teach Bennett a lesson. Just as the game is about to begin, the team decides to forgive Bennett and they win the game for Upton.
Paul Crewe (Adam Sandler) is a former NFL player disgraced for shaving points in a big game. One night, he gets drunk and goes joyriding in his girlfriend's Bentley, totals it, gets arrested, and is sentenced to three years in a Texas Federal Prison for violating his parole.
Mickey et son équipe de football américain, les Manglers, jouent contre les Alley Cats de Pat Hibulaire. La fin de partie est très serrée avec un 96 ex-aequo. Mickey se doit de marquer le dernier point.
Wide receiver Phil Elliott (Nolte) plays for a 1970s era professional football team based in Dallas, Texas named the North Dallas Bulls, which closely resembles the Dallas Cowboys.