Chitra (Nayantara), a medical student and her friends are working on a project about the human brain. She wants to investigate the curious case of Sanjay Ramaswamy (Suriya), a (former) notable Chennai based businessman, who is reported to have anterograde amnesia. Her professor denies access to Sanjay's records as it is currently under criminal investigation. Chitra, nonetheless, decides to investigate the matter herself.
New Orleans, 1937: Catherine Holly (Elizabeth Taylor) is a young woman institutionalized for a severe emotional disturbance that occurred when her cousin, Sebastian Venable, died under questionable circumstances while they were on summer holiday in Europe. The late Sebastian's wealthy mother, Violet Venable (Katharine Hepburn), makes every effort to deny and suppress the potentially sordid truth about her son and his demise. Toward that end, she attempts to bribe the state hospital's administrator, Dr. Lawrence J. Hockstader (Albert Dekker), by offering to finance a new wing for the underfunded facility if he will coerce his brilliant young surgeon, Dr. John Cukrowicz (Montgomery Clift), into lobotomizing her niece, thereby removing any chance that the events surrounding her son's death might be revealed by Catherine's "obscene babbling.
In 1975, 13-year-old Christiane Felscherinow lives with her mother and little sister in a small apartment in a typical multi-story concrete social-housing building in a dull neighbourhood in the outskirts of West Berlin. She's sick and tired of living there and has a passion for singer David Bowie. She hears of Sound, a new disco in the city centre, labelled as the most modern discothèque in Europe. Although she's legally too young to go there, she dresses up in high heels, wears makeup, and asks a friend from school, who hangs out there regularly, to take her, too. At the disco, she meets Detlef, who is a little older and is in a clique where everybody experiments with various drugs. At first she takes pills and LSD, and goes to a David Bowie concert in which she meets Babsi, a girl of her same age and tendencies, and tries heroin for the first time by snorting it. But soon after Christiane falls in love with Detlef, and in order to be closer to him begins using heroin on a regular basis, gradually delving deeper into the drug and ending up as a full-blown addict. After her 14th birthday her time at home is replaced with time spent at her cohorts' unkempt apartment, she is also drawn to the seedy Bahnhof Zoo scene, a large railway and subway station notorious for the drug and sex trade in its underpasses and backalleys. There she also begins prostituting herself, with handjobs at first, imitating her boyfriend who also sells himself to homosexual clients on a regular basis. She steals at home, too, sells all her possessions, and debases herself to abysmal levels. In one of the crudest scenes, Christiane is jumped in a filthy, blood- and urine-soaked cubicle by an older junkie who forces her to surrender her loaded syringe and proceeds to inject himself with it right in the neck in front of a terrorised elder woman who happens to be in the lavatories too.
A young woman, Janice, is living with her restrictive and conservative parents, who lead a dull working-class life, and consider their daughter to be "misbehaving" whenever she's trying to find her own way in life. When she becomes pregnant, they force her into abortion, and hypocritically blame her for "upsetting them" when she is unable to cope with the emotional and mental effect this has on her. Janice is subjected to shockingly self-righteous and ignorant doctors.
The film starts as Angela sits on a subway. The train halts and passengers are told to evacuate, as a man has just stepped in front of the tracks and died. While being led out of the station, Angela begins to move towards the tracks to see the man's remains. She is warded away at the last instant. Angela is a university student in Madrid, writing a thesis on audiovisual violence in the family. At a thesis meeting, she asks her thesis director, Figueroa, to help her find the most violent videos in the school's library. After class, Angela seeks out the help of a fellow student, Chema, who is known for his collection of violent and pornographic videos. As Angela begins to watch violent films with Chema, Professor Figueroa finds a tape in a hidden hallway of the school's audiovisual archives. The next day, Angela finds Figueroa dead of apparent heart failure in the university's viewing room, a video tape in the player. Angela takes the tape and leaves for class. She later learns that Figueroa died of an asthma attack, and that a younger professor, Castro, will now be directing her thesis project. Angela goes to Chema's house to watch the stolen film, and Chema realizes that this is a snuff film, or a film of someone actually being murdered. As they watch the women being tortured, killed and disemboweled, Chema realizes that the women in the film was named Vanessa, a girl who attended their university and went missing two years ago. Chema and Angela are also able to determine which kind of camera the killer used, and XT 500, based on the quality of its digital zoom, and that the film was shot in someone's garage.
A young man, David (Whannell), is in an interrogation room talking to an unnamed, unsympathetic police officer (Paul Moder). David is in handcuffs, and he has blood on his face and shirt. He is smoking a cigarette. He tells the officer that after he finished his work as an orderly at the hospital, he was knocked unconscious and taken to a large room.
Carrie White (Sissy Spacek), a shy and friendless 17-year-old girl, is the scapegoat and outcast of her school in North Carolina. At home, she is abused by her mentally unstable mother Margaret (Piper Laurie), who is a Christian fundamentalist.
After claiming he is an extraterrestrial from the planet 'K-PAX', 1,000 light years away in the Lyra constellation, prot (uncapitalized and pronounced with a long O) is committed to the Psychiatric Institute of Manhattan. There, psychiatrist Dr. Mark Powell attempts to cure him of his apparent delusions. However, prot is unwavering in his ability to provide cogent answers to questions about himself, K-PAX and its civilizations. Dr. Powell introduces him to a group of astrophysicists, to whom prot displays a level of knowledge that puzzles them.
Having just served five years in prison for a crime he did not commit, Billy Brown (Vincent Gallo) kidnaps a young tap dancer named Layla (Christina Ricci) and forces her to pretend to be his wife. Layla allows herself to be kidnapped and it is clear she is romantically attracted to Billy from the start, but Billy all the while is compelled to deal with his own demons, his loneliness and his depression.
Schoolteacher and family man Ed Avery (James Mason), who has been suffering bouts of severe pain and even blackouts, is hospitalized with what is diagnosed as polyarteritis nodosa, a rare inflammation of the arteries. Told by doctors that he probably has only months to live, Ed agrees to an experimental treatment: doses of the hormone cortisone.
Charles Plumpick (Bates) is a kilt-wearing Scottish soldier who is sent by his commanding officer to disarm a bomb placed in the town square by the retreating Germans.
Englar Alheimsins, which has often been called an Icelandic One Flew Over the Cuckoo's Nest, is the story of an Icelandic man named Páll (Ingvar E. Sigurðsson). After his girlfriend leaves him he's slowly turning into a state of madness and depression. His parents decide to send him to a mental hospital where he meets Óli (Baltasar Kormákur), who believes he's the songwriter for The Beatles, Viktor (Björn Jörundur Friðbjörnsson), who signs cheques with the signature of Adolf Hitler, and other special characters. The movie depicts his struggle, in and out of the mental hospital.
Yves est considéré par l’institution hospitalière comme « inéducable et irrécupérable ». Pris en charge en 1958 par Fernand Deligny, éducateur singulier dont les tentatives de cures libres refusaient l’ordinaire des méthodes psychiatriques, Yves devient en 1962 le personnage central d’un film tourné dans les Cévennes.
Yves et Richard s’évadent de l’asile.
En se cachant, Richard tombe dans un trou.
La fille d’un ouvrier de la carrière proche observe Yves resté seul et le ramène à l’asile.
In April 1967, 18-year-old Susanna Kaysen (Winona Ryder), a depressed and unmotivated girl is checked into Claymoore psychiatric hospital, after having a nervous breakdown and taking an overdose of aspirin. She denies the accusation from many that she was attempting to commit suicide, claiming that she was only trying to get rid of her headache. Susanna's mother and father, along with the nurses and therapists, are surprised when Susanna confesses that she does not actually want to go to college and would like to become an independent, free spirited writer.
Kevin Wendell Crumb souffre d'un trouble dissociatif de l'identité. Il échange régulièrement avec sa psychiatre dévouée, le docteur Fletcher, qui a déjà pu distinguer vingt-trois personnalités différentes s'exprimer à tour de rôle durant leurs conversations. Selon Fletcher, Kevin aurait subi des maltraitances et des humiliations au cours de son histoire et une 24 e personnalité, plus sombre et plus menaçante que toutes les autres, nommée « la Bête », demeure encore enfouie. Le docteur Fletcher met en exergue le fait que son patient s'est forgé ces nombreuses personnalités différentes dans un besoin existentiel de se protéger des autres. La situation se complique lorsque Kevin enlève trois jeunes filles.