Scooby-Doo, Shaggy, and Scrappy-Doo are on their way to a Miss Grimwood's Finishing School for Girls, where they have been hired as gym teachers. Once there, however, they find that it is actually a school for girl ghouls. The pupils include Sibella, the daughter of Count Dracula; Elsa Frankenteen, the daughter of Frankenstein's monster, Winnie, the daughter of The Wolfman; Phantasma (usually called Phanty for short), the daughter of a phantom, possibly The Phantom of the Opera; and Tanis, the daughter of The Mummy - all parodies/tributes to the Universal Monsters of the 1930s-40s. Other residents of the school are a floating white hand; an octopus, who is the school's butler; Legs, a spider that helps with the upcoming volleyball match; Miss Grimwood, the headmistress; and her pet dragon Matches (who dislikes Scooby at first, but later becomes friends, and has a strong friendship with Scrappy). Shaggy and Scooby want no part of this at first, but eventually they agree to stay as teachers.
The Monster Squad is a society of young pre-teens who idolize classic monsters and monster movies and hold their meetings in a tree clubhouse. Club leader Sean (Andre Gower), whose five-year-old sister Phoebe (Ashley Bank) desperately wants to join the club, is given the diary of legendary monster hunter Dr. Abraham Van Helsing (Jack Gwillim), but his excitement abates when he finds it is written in German. Sean, his best friend Patrick (Robby Kiger), and the rest of the Monster Squad visit an elderly man, known as the "Scary German Guy" (Leonardo Cimino), actually a kind gentleman, to translate the diary. When the Monster Squad wonders how the German man is so knowledgeable about Van Helsing's battle with monsters, he wryly comments that "he has some experience with monsters" and his shirt sleeve briefly reveals a Concentration camp number tattoo.
Through her stepsister Claire Clairmont (Miriam Cyr), Mary Godwin (Natasha Richardson) and her future husband Percy Shelley (Julian Sands) came to know Lord Byron (Gabriel Byrne). During the summer of 1816, Lord Byron invited them to stay for a while at Villa Diodati in Switzerland. There they met Byron's physician friend, Dr. John Polidori (Timothy Spall). On June 16th, while a storm raged outside, the five of them amused themselves by telling ghost stories and revealing private skeletons. From Mary's previous experience of miscarriage came the desire to raise her child from the dead, which led to the creation of the Frankenstein monster. From Polidori's homosexuality, suicidal thoughts, and fascination with vampires came the story "The Vampyre".
Jack Harrison (Goldblum) and Gil Turner (Begley) are writers for The Sensation, a supermarket-grade tabloid run by Turner's father, Mac (Norman Fell). Jack is a more serious journalist using The Sensation as a stepping stone to a better career, while Gil is a gangling yes-man ever ready to win his father's approval.
The film begins with Baron Charles Frankenstein (Sting), his monster (Clancy Brown), Dr. Zalhus (Quentin Crisp), and his assistant Paulus (Timothy Spall) creating a female mate named Eva (Jennifer Beals) for the monster. Eva is physically identical to a human and lacking the deformities of the monster. As such, she is revolted by the monster and rejects him. This causes the monster to fly into a rage and destroy Frankenstein's laboratory. Frankenstein, believing himself and Eva to be the only survivors, flees with her back to Castle Frankenstein. He tells everyone, including Eva, that she was an amnesiac he found in the woods. There he decides to take Eva for himself and pursues the goal of making her a perfect human mate.
Victor Frankenstein (played by Barret Oliver) is a young boy who creates movies starring his dog, Sparky (a Bull Terrier, whose name is a play on the use of electricity in the film). After Sparky is hit by a car, Victor learns at school about electrical impulses in muscles and is inspired to bring his pet back to life. He creates elaborate machines which bring down a bolt of lightning that revives the dog. While Victor is pleased, his neighbors are terrified by the animal, and when the Frankensteins decide to introduce the revitalized Sparky to them they become angry and terrified.
Castle Frankenstein has been empty for years and the local council is planning to repossess it, when the Frankenstein family return, seeking to find hidden treasure, and to re-animate the Frankenstein monster.
When a hot air balloon crashes on a remote and uncharted island, the four balloonists and their dog Melvin are captured by a pair of drunken old pirates who take them to the hilltop laboratory home of Dr. Frankenstein's modern-day descendant Sheila Frankenstein (Katherine Victor) who is carrying on the family tradition by turning shipwrecked sailors into pre-programmed bloodless, black-garbed zombies who must wear sunglasses to protect their weird white eyes from light.
The film centers around the life of Victor Frankenstein. After creating the monster together with his partner Zuckel, the monster attacks the assistant and falls from a cliff. Assuming the monster is dead, Victor returns to his wife Elizabeth and daughter Emily. A police inspector named Bellbeau investigates some mysterious mutilations killings, and Victor is blackmailed by his former assistant, who lost an eye in his fight with the monster.
The film begins with the Munster family making a visit to the wax museum. They take a picture of themselves standing next to their wax replicas. When the family leaves, the statues in the museum (which are actually robots) mysteriously come to life and begin wreaking havoc across the city. Herman and Grandpa are then arrested for various crimes they did not commit and try to clear their names in time for the Halloween celebration at the Munster home.
Dr. Victor Frankenstein creates a monster to show his scientific theories, but soon leaves him. So the scientist tries to rebuild his live getting married with Janet, and retires to his castle with Igor. However the monster goes back to haunt Frankenstein, and so Victor finds out that the monster has ferocious sexual orientation to Janet. Frankenstein then calls the servant Igor to readjust the monster, but also Igor takes advantage of Janet...
Baron Victor Frankenstein (Cushing) is housed at an insane asylum where he has been made a surgeon at the asylum, and has a number of privileges, as he holds secret information on Adolf Klauss, the asylum's corrupt and perverted director (John Stratton). The Baron, under the alias of Dr. Carl Victor, uses his position to continue his experiments in the creation of man.
Dr. Frederick Frankenstein (Gene Wilder) is a physician lecturer at an American medical school and engaged to the tightly wound socialite Elizabeth (Madeline Kahn). He becomes exasperated when anyone brings up the subject of his grandfather, the infamous mad scientist. To disassociate himself from his forebear, Frederick insists that his surname is pronounced "Fronkensteen."
A neanderthal man is lynched by villagers and a Count Frankenstein brings the monster back to life. Trying to avoid detection from the authorities and the locals, his creation escapes and wreaks havoc.