Barbara Gordon traque les criminels de Gotham City dans le costume de Batgirl. Une nuit, elle tente d'arrêter des braqueurs seule mais échoue ; Batman intervient et capture l'un des voleurs en fuite. Les deux justiciers identifient l'organisateur : Paris Franz, neveu du parrain du crime Lord Francesco, qu'il souhaite évincer pour prendre sa place, et qui commence à être obsédée par Batgirl. Batman demande à sa protégée de le laisser faire mais elle refuse. Quand Franz piège Batgirl en la menant vers le cadavre de Francesco, Batman lui interdit de s'impliquer dans l'affaire. Furieuse, Batgirl commence à frapper Batman et le plaque au sol avant de l'embrasser, puis ils couchent ensemble. La nuit sème la confusion dans la relation entre Batman et Batgirl. Franz se manifeste à nouveau, piégeant Batman, et Batgirl intervient mais manque de le tuer. Barbara se rend compte que Batman avait raison et abandonne son costume.
Un soir à Gotham City, le Joker et Harley Quinn dérobent une statue chez un antiquaire. Celle-ci, sans réelle grande valeur, est en fait un objet fait de kryptonite (le point faible de Superman). Le Joker se rend ensuite à Métropolis afin de conclure un marché avec le milliardiare Lex Luthor : éliminer Superman en l'échange d'un milliard de dollars. Batman et Superman vont ainsi devoir mettre leur force en commun afin de vaincre leurs deux plus redoutables ennemis respectifs...
Après avoir participé à l'affrontement entre Iron Man et Captain America, le prince T'Challa retourne chez lui dans la nation africaine reculée et technologiquement avancée du Wakanda, pour servir son pays en tant que nouveau roi. Cependant, le pouvoir de T'Challa va bientôt être défié par des membres de son propre pays. Quand deux ennemis conspirent pour détruire le Wakanda, la Panthère noire doit s'allier à l'agent de la CIA Everett K. Ross et aux membres du Dora Milaje, les forces spéciales du Wakanda, pour éviter que le pays ne soit emporté dans un conflit mondial.
À la suite des événements de Captain America : Civil War (2016) et avant ceux de Avengers: Infinity War (2018), Natasha Romanoff se retrouve seule et contrainte à affronter son passé.
A flying squadron of World War II veterans, The International Brotherhood, is a private flying investigative force led by Blackhawk. They uncover a gang of underworld henchmen, led by the notorious foreign spy Laska, who reports to The Leader, a mystery man. During the a serial's 15 chapters, Blackhawk and his flying squadron set about bringing these criminals to justice.
Over the two years since the death of Deacon Frost, Blade (Wesley Snipes), the Daywalker, a vampire unaffected by sunlight and who chooses to defend humans and fight other vampires, has been trying to find his mentor Whistler (Kris Kristofferson), who survived his suicide attempt in the first crisis. Blade has been sweeping across Russia and eastern Europe, enlisting the aid of a young man, Scud (Norman Reedus), to design him a new line of gadgetry and weaponry. Blade carves his way through a large gang of vampires, sparing one, Rush (Santiago Segura), when he promises to reveal Whistler's location. Blade tells Rush he will be back for him. Blade finds Whistler locked in a tank by a gang of vampires who were keeping him alive to torture. Blade rescues Whistler and brings him back to the lair, ridding the latter's vampirism with a cure developed by Dr. Karen Jenson.
A group of vampires look for the hidden resting place of Drake, also known as Dracula—the genetic "father" of their species. They find him in a Syrian ziggurat tomb, although not before, in a moment of blood lust, he kills one of them. The vampires capitalize on Blade's reputation as a serial killer and frame him for the killing of a familiar. During the ensuing manhunt, the FBI locate Blade's latest hideout, and, during the siege, Abraham Whistler dies. With his mentor gone and surrounded by human authorities, Blade allows himself to be captured and arrested.
Raymond « Ray » Garrison, alias Bloodshot, est un ancien soldat. Suite à l'injection de nanites dans son sang, il est doté de pouvoirs comme la régénération et la métamorphose. Alors que sa mémoire a été effacée à plusieurs reprises, Bloodshot finit par découvrir qui il est vraiment. Il décide alors de se venger de ceux qui lui ont fait subir cette expérience.
In 1936 Fascist Italy, the government kidnaps a boy, Tadzio de Santis (Massimilio Massimi), and kills his family. The child is needed for an experimental project to create a Fascist supersoldier. Dr. Maria Vaselli (Carla Cassola) objects to using Tadzio, and, under the cover of gunfire, flees to the United States to offer her services to the Americans.
Steve Rogers is a character in contemporary times whose father was a 1940s government agent. The very patriotic attitude of Steve's father earned him the nickname Captain America, and his father is spoken of as having been murdered. Rogers, a former Marine now making what little living he makes as an artist, is inspired by this story to sketch a super-hero. After receiving potentially fatal injuries in an accident, he is administered an experimental chemical called the FLAG — Full Latent Ability Gain—formula (at one point referred to as a "super-steroid") which not only saves his life but also enhances his body with heightened strength and reflexes. These new abilities lead Dr. Simon Mills (Len Birman), the research biochemist and intelligence official who had told Rogers about his father, to recruit him and give Steve a costume based on his drawing. As Captain America, he also makes significant use of a specialized reconstruction of the van he has been driving, out the rear of which can be launched a modified motorcycle. Its functions include a rocket thrust for a fast start out of the van, a jet boost for increased speed, a setting to allow the bike to be ridden with less noise for stealthier movement and a hang glider structure which can allow the bike to glide to the ground with some forward momentum, although it must be jettisoned upon landing.
Le Soldat de l'Hiver (alias Bucky Barnes) a autrefois été reconditionné dans une base militaire soviétique sibérienne et hypnotisé à l'aide de certains mots. Quiconque prononce ces mots en russe plonge le Soldat de l'Hiver en transe et peut lui donner n'importe quel ordre sans qu'il puisse désobéir. C'est ainsi qu'en 1991, le Soldat de l'Hiver a provoqué l'arrêt brutal d'une voiture pour s'emparer dans son coffre d'une valise avec un étrange contenu.
Two years after the Battle of New York, Steve Rogers works in Washington D.C. for the espionage agency S.H.I.E.L.D. under Director Nick Fury, while adjusting to contemporary society. Rogers and Agent Natasha Romanoff are sent with S.H.I.E.L.D.'s counter-terrorism S.T.R.I.K.E. team, led by Agent Rumlow, to free hostages aboard a S.H.I.E.L.D. vessel from Georges Batroc and his mercenaries. Mid-mission, Rogers discovers Romanoff has another agenda: to extract data from the ship's computers for Fury. Rogers returns to the Triskelion, S.H.I.E.L.D.'s headquarters, to confront Fury and is briefed about Project Insight: three Helicarriers linked to spy satellites, designed to preemptively eliminate threats. Unable to decrypt the data recovered by Romanoff, Fury becomes suspicious about Insight and asks senior S.H.I.E.L.D. official Alexander Pierce to delay the project.
A rash of suspicious suicides among scientists and businessmen, all found holding a small scarab, gets the attention of Mayor Randolph. He demands that Police Commissioner Dryden and District Attorney Grant Gardner get to the bottom of the case, while openly wishing that Captain America, a masked man who has helped defeat crime in the past, were around to solve the mystery. Gail Richards, Grant Gardner's secretary, investigates and realises someone knows of the "Purple Death", a hypnotic chemical responsible for the suicides. However he then pulls out a gun and takes her into another room. He then orders an associate to tie her up. The D.A. realises she is there and forces the man to take him to her. He finds her tied up and gagged. He frees her but it is threatened that the purple death will be dropped killing them all. But the D.A. shoots him then gets out of the room with Gail.