Kathryn Kidman is attacked and apparently killed by a werewolf. Many years later, her son Will is living with his father and is enrolled in a high school with an advanced security system. His best friend, Sachin, is making a horror film and is planning to broadcast it by hacking into news channels illegally. Will has a crush on Eliana Wynters, but her current boyfriend scares him away.
The film is set in Bailey Downs, a suburb where a rash of dog killings has been occurring. Brigitte and Ginger Fitzgerald are teenage sisters who harbor a fascination with death and, as children, formed a pact to die together. One night, while on the way to kidnap a dog owned by school bully Trina Sinclair, Ginger begins her first period, which results in the girls being attacked by the creature responsible for the maulings. The creature wounds and bites Ginger, but Brigitte rescues her. As the girls flee, the creature is run over by a van belonging to Sam MacDonald, a local drug dealer. Ginger decides not to go the hospital as her wounds heal quickly.
Each spring, a party from a fort travels to Hudson Bay to trade pelts for winter provisions, but, in 1815, nobody returns. Brigitte and Ginger are lost with their horse in the Canadian wilderness when they come across a seemingly abandoned camp. An elderly Indian woman, who warns them that they must kill a boy to prevent one sister from killing the other, gives them each a pendant. As their startled horse runs off, Brigitte's foot is caught in a trap. Ginger seeks help, but the hunter frees Brigitte before she returns. He leads them to Fort Bailey, where they take refuge. Ginger says they are the daughters of a drowned trader and are seeking passage east.
After the events of the first film, Brigitte Fitzgerald uses monkshood extract to fight the effects of the lycanthropy that transformed her sister into a werewolf. Brigitte shaves her body, cuts her arm with a scalpel, and logs the data about her healing ability. Ginger, her dead sister, appears as an apparition and warns her that monkshood is only a treatment, not a cure. After Brigitte injects a second dose of monkshood, she senses the presence of a male werewolf that has been stalking her. She quickly packs and open the door, only to find Jeremy, a flirtatious librarian who has brought to her several books she attempted to check out earlier. The second injection causes toxic shock, and Jeremy attempts to bring her to the hospital; however, the male werewolf mauls him to death. Brigitte stumbles down the street and collapses in the snow.
Lord Voldemort is tightening his grip on both the wizarding and Muggle worlds and has chosen Draco Malfoy to carry out a secret mission. Severus Snape makes an Unbreakable Vow with Draco's mother, Narcissa, to protect Draco and fulfill the assignment if he fails.
Harry Potter, now aged 13, has been spending another dissatisfying summer at Privet Drive. When Uncle Vernon's sister, Marge, insults Harry's parents, he becomes angry and accidentally causes her to inflate and float away. Harry flees with his luggage, fed up with his life with the Dursleys. The Knight Bus delivers Harry to the Leaky Cauldron, where he is forgiven by Minister of Magic Cornelius Fudge for using magic outside of Hogwarts. After reuniting with his best friends Ron and Hermione, Harry learns that Sirius Black, a convicted supporter of the dark wizard Voldemort, who murdered Harry's parents, has escaped Azkaban prison, intending to kill Harry.
In the aftermath of the death of Dracula's wife Martha (Jackie Sandler) at the hands of an angry mob, Count Dracula (Adam Sandler) designs and builds a massive five-star hotel in Transylvania in which to raise his daughter Mavis (Selena Gomez) and to serve as a getaway for all the world's monsters.
A short time after the first film, Mavis (Selena Gomez) and her fiance Johnny (Andy Samberg) are married, with the approval of her father Dracula (Adam Sandler) and the world has become aware of (and unfased by) the existence of monsters. Mavis later reveals to Drac that she is pregnant and a year later, she gives birth to a son named Dennis (Asher Blinkoff), who befriends Wayne's werewolf pup daughter Winnie (Sadie Sandler). Nearing his fifth birthday, Dennis has yet to grow his fangs and Drac worries that his grandson might not gain vampire powers. Noticing the dangers of Transylvania, Mavis starts to consider raising Dennis where Johnny grew up, much to Drac's disapproval.
Quelques mois après Hôtel Transylvanie 2, tous les membres de la famille de Dracula et ses amis se réunissent pour partir en vacances à bord d'un luxueux bateau de croisière. Pendant la croisière, Dracula tombe amoureux du capitaine qui n'est autre que la descendante du professeur Van Helsing, le tristement célèbre tueur de monstres.
Dr. Bela Reinhardt (Ron Chaney) is a mad doctor who has invited five people to his castle to determine which of them shall inherit his estate. He has arranged for a competition of sorts. The winner will be chosen by process of... elimination.
Pete Dumond, Chief Make-up Artist for 25 years at American International Studios, is fired after the studio is purchased by NBN Associates. The new management from the East, Jeffrey Clayton and John Nixon, plan to make musicals and comedies -- instead of the horror pictures for which Pete has created his remarkable monster make-ups and made the studio famous. In retaliaton, Pete vows to use the very monsters these men have rejected to destroy them. By mixing a numbing ingredient into his foundation cream and persuading the young actors that their careers are through unless they place themselves in his power, he hypnotizes both Larry Drake and Tony Mantell (who are playing the characters Teenage Werewolf and Teenage Frankenstein, respectively, in the picture Werewolf Meets Frankenstein,currently shooting on the lot).
The plot involves an overnight passenger train, the Alpha Trax, which leaves London at midnight and under a full moon. An hour after departure, the train is travelling through a remote and forested part of the English countryside, in a mobile communication "dead zone". Here the train is forced to undergo an emergency brake to prevent a derailment when a deer runs onto the track. Old-timer passenger Ged (Duncan Preston) recalls a similar event happening in the exact same spot - the Great Thornton Forest Rail Crash of 1963 - whereby all the passengers were found dismembered and partially eaten the following morning.
Karen White (Dee Wallace) is a Los Angeles television news anchor who is being stalked by a serial murderer named Eddie Quist (Robert Picardo). In cooperation with the police, she takes part in a scheme to capture Eddie by agreeing to meet him in a sleazy porno theater. Eddie forces Karen to watch a video of a young woman being raped, and when Karen turns around to see Eddie she screams. The police enter and shoot Eddie, and although Karen is safe, she suffers amnesia. Her therapist, Dr. George Waggner (Patrick Macnee), decides to send her and her husband, Bill Neill (Christopher Stone), to the "Colony", a secluded resort in the countryside where he sends patients for treatment.
Ben White (Reb Brown) attends the funeral of his sister, journalist Karen White, the heroine of the previous film. Ben meets both Jenny Templeton (Annie McEnroe), one of Karen's colleagues, and Stefan Crosscoe (Christopher Lee), a mysterious interloper who tells him Karen was a werewolf. Providing videotaped evidence of the transformation – and turning up to destroy Karen as her undead body rises from the grave – Crosscoe convinces Ben and Jenny to accompany him to Transylvania to battle Stirba (Sybil Danning), an immortal werewolf queen. Along the way, the trio encounter Mariana (Marsha Hunt), another lusty werewolf siren, and her minion Erle (Ferdy Mayne).
In this movie, Australian werewolves have evolved separate from the rest of the werewolf population. They are marsupials - the female werewolves give birth to partly developed young which then makes its way to a pouch for further development.