In 1933, at the height of the Great Depression, New York City vaudeville actress Ann Darrow has lost her job and is hired by financially troubled filmmaker Carl Denham to star in his new film. Ann signs on when she learns her favorite playwright, Jack Driscoll, is the screenwriter. As their tramp steamer, the SS Venture, makes the lengthy journey to the remote and mysterious Skull Island, Ann and Jack fall in love. Captain Englehorn begins having second thoughts about the voyage, prompted by crew speculation of trouble ahead.
A saber-toothed squirrel (known as Scrat) is trying to find a place to store his prized acorn. Eventually, as he tries to stomp it into the ground, he causes a large crack in the ground that extends for miles and miles and sets off a large avalanche. He barely escapes, but finds himself stepped on by a herd of prehistoric animals. The animals are trying to avoid the ice age by migrating south. Sid, a clumsy ground sloth left behind by his family, decides to move on by himself but is attacked by two Brontops whom he angered. Sid is soon saved by Manfred ("Manny"), an agitated mammoth who fights them off and is heading north. Not wanting to be alone and unprotected, Sid follows Manny. Meanwhile, Soto, the leader of a Smilodon pride, wants revenge on a group of humans by eating the chief's baby son, Roshan, alive. Soto leads a raid on the human camp, during which Roshan's mother is separated from the rest and jumps down a waterfall when cornered by Soto's lieutenant, Diego. For his failure, Diego is sent to find and retrieve the baby.
James Bond infiltrates a North Korean military base, where Colonel Tan-Sun Moon is illegally trading weapons for African conflict diamonds. After Moon's assistant Zao discovers that Bond is a British agent, the colonel attempts to kill Bond and a hovercraft chase ensues, which ends with Moon's apparent death. Bond survives, but is captured by North Korean soldiers and imprisoned by the Colonel's father, General Moon.
In Russia, the media covers Tony Stark's disclosure of his identity as Iron Man. Ivan Vanko, whose father Anton Vanko has just died, sees this and begins building a miniature arc reactor similar to Stark's. Six months later, Stark is a superstar and uses his Iron Man suit for peaceful means, resisting government pressure to sell his designs. He re-institutes the Stark Expo in Flushing Meadows to continue his father Howard's legacy.
On an expedition in Antarctica, paleoclimatologist Jack Hall and his colleagues Frank and Jason are drilling for ice-core samples on the Larsen Ice Shelf for the NOAA when the shelf breaks off.
In Thebes, Egypt, 1290 BC, high priest Imhotep engages in an affair with Anck-su-Namun, the mistress of Pharaoh Seti I. When the Pharaoh discovers their tryst, Imhotep and Anck-su-Namun kill him. As Seti's guards arrive, Imhotep flees while Anck-su-Namun kills herself, intending for Imhotep to resurrect her. After Anck-su-Namun's burial, Imhotep and his priests steal her corpse and travel to Hamunaptra, the city of the dead, where they begin the resurrection ceremony. However, the group is intercepted by Seti's bodyguards, the Medjai, before the ritual could be completed, and Anck-su-Namun's soul is sent back to the Underworld. Imhotep's priests are all mummified alive. Imhotep himself is sentenced to immortal agony, condemned to suffer the Hom Dai curse: having his tongue removed and then being buried alive with flesh eating scarab beetles. Imhotep is buried under high security, sealed away in a sarcophagus at the feet of a statue of the Egyptian god Anubis, and kept under strict surveillance by the Medjai, since if Imhotep were ever to resurrect, the entire world would be doomed.
Thorin and his company are being pursued by Azog and his Orc party following the events of the previous film. They are ushered along by Gandalf to the nearby home of Beorn, a skin-changer who can take the form of the bear. That night, Azog is summoned to Dol Guldur by the Necromancer, who commands him to marshal his forces for war. Azog then delegates the hunt for Thorin to his son Bolg. The following day, Beorn escorts the company to the borders of Mirkwood, where Gandalf discovers Black Speech imprinted on an old ruin. This coincides with a telepathic message from Galadriel urging him to investigate the tombs of the Nazgûl. He warns the company to remain on the path and leaves them. Upon entering the forest they lose their way and are ensnared by giant spiders. Bilbo then sets about freeing the dwarves with the help of his recently acquired invisibility ring. He subsequently drops the Ring and first begins to understand its dark influence after he brutally kills a centipede-like creature to retrieve it.
Fotoula "Toula" Portokalos (Nia Vardalos) is going through an early midlife crisis. At thirty, having had her childhood, adolescence and adult life plagued by bad luck, she feels that she is the only woman in her family who has "failed" at being a typical Greek girl. Her family expects her to be more like her 33-year-old sister Athena (Stavroula Logothettis) and marry a Greek boy, make Greek babies, and "feed everyone until the day she dies." Instead, Toula is stuck working in the family restaurant in Chicago, "Dancing Zorba's." Frumpy and cynical, she fears that she is doomed to be stuck with her life as it is and always has been. One day while at the restaurant, Toula briefly becomes enamored with and embarrasses herself in front of Ian Miller (John Corbett), a handsome school teacher.
Charlie Bucket (Freddie Highmore) is a kind and loving boy living in poverty with his parents (Noah Taylor and Helena Bonham Carter) and four bedridden grandparents. They all rely on his father for income, employed at a toothpaste factory, responsible for putting the caps on the tubes. Down the street is Willy Wonka's (Johnny Depp) chocolate factory, which reopened after industrial espionage forced him into seclusion and to sack his employees. Charlie's Grandpa Joe (David Kelly) worked for Wonka before the termination.
Larry Daley (Ben Stiller) is divorced, unable to keep a stable job, and has failed at many business ventures. His ex-wife (Kim Raver) believes that he is a bad example to their ten-year-old son Nick (Jake Cherry), and Larry fears that Nick respects his future stepfather, bond trader Don (Paul Rudd), more than him.
Following their successful Rio heist, Dominic "Dom" Toretto and his professional criminal crew have fled around the world: Dom lives with Elena; his sister Mia lives with Brian O'Conner and their son, Jack; Gisele and Han live in Hong Kong; and Roman and Tej live in luxury.
John Hancock (Will Smith) is an alcoholic man with superhero powers, including flight, invulnerability, and super-strength. Though he uses his powers to stop criminals in his current residence of Los Angeles, his activity inadvertently causes millions of dollars in property damage due to his constant intoxication. As a result, he is routinely jeered at the crime scenes. Hancock also ignores court subpoenas from the city of Los Angeles to address the property damage he has caused.
William "Will" Thacker (Hugh Grant) owns an independent travel bookshop in Notting Hill. He is divorced and shares his house with an eccentric, uninhibited Welshman named Spike (Rhys Ifans).
The story is set in the Valley of Peace, a fictional land in ancient China inhabited by anthropomorphic animals. Po, a giant panda, is a kung fu fanatic who idolizes the Furious Five — Tigress, Monkey, Mantis, Viper, and Crane — a quintet of kung fu masters trained by the red panda Master Shifu. As he helps his goose father Mr. Ping in his noodle restaurant, Po is unable to pursue his dream of becoming a kung fu master himself.