Ten years after tracking down serial killer Jame Gumb, FBI Special Agent Clarice Starling (Moore) is unjustly blamed for a bungled drug raid. Starling and her connection to Hannibal Lecter (Hopkins) come to the attention of Lecter's only surviving victim, Mason Verger (Gary Oldman), a wealthy child molester whom Lecter left paralyzed and horribly disfigured during a therapy session.
In 1891, London detective Sherlock Holmes (Robert Downey, Jr.) and his partner and flatmate Dr. John Watson (Jude Law) race to prevent the ritual murder of a woman by Lord Blackwood (Mark Strong), who has killed five other young women similarly. They stop the murder before Inspector Lestrade (Eddie Marsan) and the police arrive to arrest Blackwood.
James Bond is driving from Lake Garda to Siena, Italy, with the captured Mr. White in the boot of his car. After evading pursuers, Bond and M interrogate White regarding his organization, Quantum. M's bodyguard Craig Mitchell, a double agent, attacks M, enabling White to escape. Bond chases Mitchell and kills him. Bond and M return to London and search Mitchell's flat, discovering through tagged banknotes that Mitchell had a contact in Haiti. Bond tracks the contact, Edmund Slate, and learns that Slate is a hitman sent to kill Camille Montes at the behest of her lover, environmentalist Dominic Greene. While observing her subsequent meeting with Greene, Bond learns that Greene is helping an exiled Bolivian General, Medrano—who murdered Camille's family—to overthrow his government and become the new president in exchange for a seemingly barren piece of desert.
A young monster named Michael "Mike" Wazowski dreams of being a scarer (a monster who enters the human world at night to scare children so their screams can be harvested for energy) when he grows up, after visiting Monsters Inc. (Monstropolis' most profitable and best-known scaring company) on a school field trip. Eleven years later, Mike is a first-year scare major at Monsters University, where he meets a monster named James P. "Sulley" Sullivan.
Austin Powers is enjoying his honeymoon with his wife, the former Vanessa Kensington. She turns out to be one of Dr. Evil's fembots, who attempts to kill Austin, then self-destructs. Austin grieves briefly, then proceeds to the hotel lobby nude and celebrates being single again.
MI6 agent James Bond meets a Swiss banker in Bilbao, Spain to retrieve money for Sir Robert King, a British oil tycoon and friend of M. Bond tells the banker that King was buying a report stolen from an MI6 agent who was killed for it, and wants to know who killed him. The banker threatens Bond, but Bond overpowers him. The banker is killed by his assistant before he can reveal the assassin's name. Bond escapes with the money.
In Los Angeles, career-focused lawyer Fletcher Reede (Carrey) loves his son Max (Cooper), but his inability to keep his promises and compulsive lying in lieu of his career often causes problems between them and with his ex-wife Audrey (Tierney), who has become involved with another man named Jerry. In court, Fletcher is willing to exaggerate the stories of his clients, and his current client, the self-centered, money-grabbing Samantha Cole (Tilly) has garnered the attention of Mr. Allen, a partner at the law firm in which Fletcher works. If Fletcher wins this case, it will bring his firm a fortune and boost his career. Fletcher lies to Max about missing his birthday due to work, when he is actually sleeping with another attorney, Miranda, in order to get a promotion. Dejected, Max makes a birthday wish that for one day his father cannot tell a lie. The wish immediately comes true, and Fletcher accidentally tells Miranda he has "had better" after they have sex.
To celebrate his upcoming marriage to Tracy Garner (Sasha Barrese), Doug Billings (Justin Bartha) travels to Las Vegas with his best friends Phil Wenneck (Bradley Cooper) and Stu Price (Ed Helms), as well as Tracy's brother and Doug's future brother-in-law Alan (Zach Galifianakis), in Doug's future father-in-law's vintage Mercedes-Benz. They stay at Caesars Palace, where they relax in the room before celebrating with a few drinks on the hotel rooftop. The next morning, Phil, Stu, and Alan awaken to find they have no memory of the previous night, and Doug is nowhere to be found. Stu is missing a tooth, their hotel suite is in disarray, a tiger is in their bathroom, a chicken in their living room, and a baby is in the closet, whom they name "Carlos". They find Doug's mattress impaled on a statue outside of their hotel and when they ask for their Mercedes, the valet delivers an LVPD police cruiser.
Lester Burnham is a middle-aged magazine writer who despises his job. His wife, Carolyn, is an ambitious real estate broker; their sixteen-year-old daughter, Jane, abhors her parents and has low self-esteem. The Burnhams' new neighbors are retired United States Marine Corps Colonel Frank Fitts and his introverted wife, Barbara. Their teenage son, Ricky, obsessively films his surroundings with a camcorder, collecting hundreds of recordings on video tapes in his bedroom. He also secretly deals marijuana, using a job as a part-time bar caterer to help keep it secret from his father. Having been previously forced into a military academy and a psychiatric hospital, Ricky is subjected by Col. Fitts to a strict disciplinarian lifestyle. Jim Olmeyer and Jim Berkley, a gay couple who live nearby, welcome the family to the neighborhood; Col. Fitts later reveals his homophobia when angrily discussing the incident with Ricky.
Four days after the events of the first film, detective James Carter is on vacation in Hong Kong, visiting his friend, Hong Kong Police Force Chief Inspector Lee, as he was sent along with Lee in saving the life of the Chinese counsel's daughter in Los Angeles. The fun is put on hold when a bomb explodes at the United States Consulate General, killing two undercover U.S. custom agents inside. Inspector Lee is assigned to the case, which becomes personal when it is discovered that it somehow involves Ricky Tan, his late police officer father's former partner. Tan, who was suspected of having a role in Lee's father's death - though the connection was never proven - is now a leader of the Triads. This, however, causes a rift between Lee and Carter, the later who simply wants to enjoy his vacation and not get into any danger.
In 2029, aboard the United States Air Force space station Oberon, Leo Davidson works closely with primates who are trained for space missions. His favorite simian co-worker is a chimpanzee named Pericles. With a deadly electromagnetic storm approaching the station, a small space pod piloted by Pericles is used to probe the storm. Pericles's pod heads into the storm and disappears. Against his commanding officer's orders, Leo takes a second pod and goes in pursuit of Pericles. Entering the storm, Leo loses contact with the Oberon and crashes on a planet called Ashlar in the year 5021. He discovers that the world is ruled by humanoid apes who can speak human language and treat human beings as slaves.
In 2805, Earth is long-abandoned and covered in heaps of garbage leftover from decades of mass consumerism, facilitated by the megacorporation Buy 'n' Large (BnL). Seven hundred years earlier, BnL evacuated Earth's population in fully automated starliners, leaving behind WALL-E trash compactor robots to clean the planet for humanity's eventual return, however the plan failed and all the bots were shut off. Only one WALL-E robot remains active, and has developed sentience after so many years of life-experience. He manages to remain active by repairing himself using parts from other inactive units.
At the White House, brainwashed teleporting mutant Nightcrawler tries to assassinate the President of the United States but fails and escapes, leaving a note demanding "mutant freedom now." At Alkali Lake, X-Men member Wolverine finds nothing left of the military base from the previous movie. He returns to Professor Xavier's school for mutants, while fellow X-Men Storm and Jean Grey find Nightcrawler with the help of Xavier and the mutant-tracking machine Cerebro.
Tourists Ben Hildebrand and Eric Kirby decide to parasail around the island of Isla Sorna. A creature of unknown species attacks and kills the boat crew as it passes through a fog bank, but Ben uncouples the line, and with Eric bound with him, he goes sailing into the wilderness.
Minions are small, yellow creatures who have existed since the beginning of time, evolving from single-celled organisms into beings who exist only to serve history's most villainous masters. They find great masters—including a T-Rex, a caveman, an Egyptian pharaoh, Dracula, and Napoleon,—but after accidentally killing nearly all of them with their incompetence, they decide to isolate themselves from the world and start a new life in Antarctica. By 1968, the lack of a master to serve drives them into depression, so Kevin, one fearless Minion, plans to find a new one for them by going back out into the world. Stuart—a bored, teenaged minion who is obsessed with guitars—joins him reluctantly, as does an over-enthusiastic Bob, whom Kevin only chooses because of no one else willing to volunteer.