The film begins In medias res, after Phineas, Ferb, Candace, Perry, and Dr. Doofenshmirtz have been nabbed by 2nd Dimension Dr. Doofenshmirtz and his sidekick Platyborg. Phineas and Ferb have a flash back to how their morning began.
At a satellite base in Northern Germany, a worker named Freidrich, who is delivering secret codes finds a Cocker Spaniel puppy outside his office. He takes the puppy inside and shows it to his Bloodhound Rex. Rex senses that something is wrong with the dog and barks at it, making the worker take him outside. Both get locked out of the office. Rex looks through the window and sees the puppy taking pictures of the secret codes and revealing itself to be an evil female hairless Sphynx cat named Kitty Galore in disguise. Rex turns out to be a dog agent and reports to HQ.
Smith is an 18-year-old film student who identifies sexually as "undeclared". He has been having strange dreams. He is going to college with his best friend, Stella, whom he has known since junior high. Smith finds a note saying that he is the "chosen son". He has a roommate, Thor, whom he lusts after, regretting that Thor is straight. Stella goes to a party with Smith, but hooks up with another girl, Lorelei. He recognizes Lorelei as one of the people in his dream. Smith notices a guy, but is distracted when a red-haired girl from his dream vomits on his shoe. The guy vanishes, but Smith gets picked up by London, a British student. They have sex, but to Smith's regret she does not want to be with him except during the sex.
In 2010, three friends are miserable with their lives: Adam Yates (John Cusack) has been dumped by yet another girlfriend, and his geeky 20-year-old nephew Jacob (Clark Duke) lives in his basement, playing Second Life, with no idea who his father is. Lou Dorchen (Rob Corddry) is a party animal way past his prime. Nick Webber-Agnew (Craig Robinson) has a dead-end job at a dog spa and an unfaithful and controlling wife named Courtney (Kellee Stewart). Lou almost dies from carbon monoxide poisoning in what his friends think is a suicide attempt. Adam and Nick sympathetically take him and Jacob to the site of some of their most memorable weekends, the Kodiak Valley Ski Resort. Upon arrival at the resort, they see that Kodiak Valley has fallen on hard times as well. They are shown to their room by a hostile one-armed bellhop named Phil Wedmaier (Crispin Glover). During a night of heavy drinking in a hot tub, they spill a can of an illegal Russian energy drink called "Chernobly" on the hot tub's controls. The next day, they wake up in 1986. They see each other as their normal age, but in their reflections and to other people, they appear as they did in 1986, except Jacob, who was not yet born. They arrive during "Winterfest '86," the weekend when Poison played to a huge crowd at the then-thriving Kodiak Resort.
Gru, a supervillain, has his pride injured when an unknown supervillain steals the Great Pyramid of Giza, an action that is described by his colleague Dr. Nefario as "making all other villains look lame." Gru decides to do better, with the assistance of Dr. Nefario, by shrinking and stealing the Moon, an idea based on his childhood dream of being an astronaut, which was always disparaged by his mother Marlena. The plan is expensive and Gru seeks a loan from the Bank of Evil, where the president Mr. Perkins is impressed by the plan, but will only provide the money if Gru can obtain the necessary shrink ray first.
A dirty bomb has decimated New York City s financial district and reduced midtown to a post-apocalyptic nightmare. The neighborhood known as Slime City has been evacuated, except for the homeless, and in the ruins of a soup kitchen four squatters discover a supply of food that transforms them into hideous slime creatures, driven to murder! Meanwhile, a greedy developer who has set his sights on Slime City hires a team of mercenaries to wipe out the creatures.
The plot loosely follows that of the original trilogy. Part 1 begins with the video recalling the start of Episode IV: A New Hope with an Imperial Star Destroyer pursuing the Tantive IV. Following the intrusion of Imperial Stormtroopers, Jar Jar Binks appears as a janitor wiping the floor of ship. At this point everyone freezes as Jar Jar passes by, and after leaving, the fighting resumes as the Rebel troopers are shot backward. Afterwards, Darth Vader walks in but slips on the wet floor; he lands on his back and is taken away on a stretcher while Jar Jar puts up a wet floor sign.
A band of ninja warriors, led by an Iga Ninja named Yamata and his comrades Jinnai and Nezumi, are assigned to investigate the crash of a mysterious object from the sky. Upon arriving at the crash site, they discover the remains of other ninjas that have been brutally torn apart. Shortly after joining forces with another band of ninjas led by the kunoichi Rin, they encounter a boy whose village was massacred by an unknown assailant. Before they can get any further explanation from him, the ninjas are attacked by the assailants, who reveal themselves to be aliens from another planet. After a grueling battle that takes the lives of several ninjas, Yamata, Rin and Jinnai kill three of the aliens, but one of them retreats and takes Jinnai with it. A cowering Nezumi rushes back to his home village, only to see the villagers massacred by the aliens. He runs for his life, but is cornered by the alien, which swiftly decapitates him as his head lands on a temple post for a crow to feed on.
The story begins in 1957 in the star-filled skies above California's Mojave Desert. It is a special night for noted astronomer Ted Lewis, who is preparing a special anniversary dinner with steaks for his beautiful, adoring wife Lana while observing the annual meteor shower of the Perseids. In another part of town, Tammy, a waitress at small local diner with big plans for the future, looks out her window and is excited to see a shooting star, which she takes as a good sign for her dreams.
A meteor shower rockets through open space. Four glowing pods are seen hiding behind the meteor shower. Suddenly the meteor shower makes a hard right and heads towards a distant planet Earth.
By the year 2056, an epidemic of organ failures has devastated the planet. The megacorporation GeneCo provides organ transplants on a payment plan. Clients who default on payments are hunted down by Repo Men: skilled assassins contracted by GeneCo to repossess organs, usually killing the clients in the process. The CEO of GeneCo, Rottissimo "Rotti" Largo (a listed in a newspaper article about his kids), discovers he is terminally ill. Rotti's three children, Luigi Largo, Pavi Largo, and Amber Sweet, who changed her last name as a stage stunt to replace a popular singer she's jealous of, bicker over who will inherit GeneCo. Rotti believes none of his children are worthy heirs, as they consistently embarrass him with their robust attitudes, and instead plans to pass on his fortune to Shilo, the daughter of his ex-fiance Marni.
The film revolves around a special team of trained secret agent animals, equipped with advanced tools that allows the mammalian members to talk to humans. The primary field team consists of guinea pigs Darwin (team leader), Juarez (martial arts), and Blaster (weapons/transportation), star-nosed mole Speckles (cyber intelligence) and fly Mooch (reconnaissance). The unit's leader Ben, orders an unauthorised infiltration of the residence of home electronics and appliances magnate, Leonard Saber, the owner of Saberling Technology, who has been under FBI investigation. The team is able to retrieve sensitive information about a sinister scheme that is set to occur in 48 hours. However, when Ben's superior arrives for his evaluation, his astonishment at the team's capabilities and technology is overcome by his indignation at Ben's unauthorized mission and the fact that the downloaded intelligence appears to be useless information about Saber's coffee makers. As a result, the government agent orders the unit shut down, the equipment seized and the animals to be used as experimental subjects to be killed. With the help of their human compatriots, Darwin, Juarez, Blaster, Mooch and Speckles escape with hopes of stopping Saber's scheme, but find themselves in a pet carrying case bound for a pet shop.
Pompous paleontologist Rick Marshall has a low-level job at the La Brea Tar Pits, three years after a disastrous interview with Matt Lauer of Today became a viral video and ruined his career. Doctoral candidate student Holly Cantrell tells him that his controversial theories combining time warps and paleontology inspired her. She shows him a fossil with an imprint of a cigarette lighter that he recognizes as his own along with a crystal made into a necklace that gives off strong tachyon energy. She convinces him to finish his tachyon amplifier and come help her on a seemingly routine expedition to the cave where Holly found the fossil, which is in the middle of nowhere. With cave gift shop owner Will Stanton they raft into the cave, where Marshall has detected high levels of tachyons. He activates the tachyon amplifier, triggering an earthquake that opens a time warp into which the raft falls. The group finds themselves in a desert, filled with various items from many eras, and without the amplifier. They rescue a primate-like creature, Cha-Ka of the Pakuni tribe, who becomes their friend and guide.
On the day of her wedding to news weatherman Derek Dietl, Susan Murphy is struck by a meteorite and its energy causes her to suddenly grow over fifty feet in height during the ceremony. She is tranquilized and awakens in a top secret government facility that houses monsters without human knowledge. She meets the warden W.R. Monger, and fellow inmates: Dr. Cockroach P.H.D., a mad scientist who became half cockroach after an experiment; B.O.B. (Benzoate Ostylezene Bicarbonate), a brainless, living mass of goo as a result of a food flavoring mutation; Insectosaurus, a mutated bug standing at over 300 feet in height, and The Missing Link, a prehistoric fish man who was thawed from deep ice; and Susan herself has been renamed to Ginormica. Meanwhile, in deep space, an alien named Gallaxhar is alerted to the presence of quantonium; a powerful energy source on Earth, and he sends a probe to retrieve it. After the probe crash lands on Earth, the president attempts to make first contact with it by playing a keyboard version of Axel F, but it begins to rampage toward San Francisco.