À la fin du XVIII siècle, dans un château proche d'un petit village français, vivait un jeune prince capricieux, égoïste et insensible. Pour avoir refusé d'abriter une fée déguisée en vieille mendiante, il est condamné à vivre sous l'apparence d'une bête monstrueuse jusqu'à ce qu'il puisse aimer une femme et s'en faire aimer en retour, ce qui le délivrerait du sortilège qui a frappé son château et ses habitants. Mais les années passent et la Bête perd peu à peu tout espoir de rompre un jour la malédiction.
In the Pride Lands of Africa, a lion rules over the animals as king. The birth of King Mufasa and Queen Sarabi's son Simba creates envy and resentment in Mufasa's younger brother, Scar, who knows his nephew now replaces him as heir to the throne. After Simba has grown into a young cub, Mufasa gives him a tour of the Pride Lands, teaching him the responsibilities of being a king and the circle of life. Later that day, Scar tricks Simba and his best friend Nala into exploring a forbidden elephant graveyard, despite the protests of Mufasa's hornbill majordomo Zazu. At the graveyard, three spotted hyenas named Shenzi, Banzai and Ed attack the cubs before Mufasa, alerted by Zazu, rescues them and forgives Simba for his actions. That night, the hyenas, who are allied with Scar, plot with him to kill Mufasa and Simba.
Long ago, a drop of sunlight became a golden flower capable of healing illness, decay and injury. For hundreds of years the flower is used by Mother Gothel to retain her youth until it is discovered by soldiers of a nearby kingdom. They use the flower to heal their ailing queen, who soon after gives birth to Princess Rapunzel. Gothel discovers that Rapunzel's hair has the flower's healing properties but that attempting to take just the hair by cutting it destroys its power, so she kidnaps Rapunzel and raises her as her own daughter in an isolated tower. Once a year, the King and Queen release sky lanterns on Rapunzel's birthday, hoping for their daughter's return.
On a golden spring day at the bank of a tranquil river, a young 12-year-old girl named Alice grows bored listening to her older 19-year-old sister read aloud from a history book of William I of England. When her sister chastises Alice's daydreaming, Alice tells her kitten Dinah that she can live in a nonsensical magical land called Wonderland. While daydreaming, Alice spots a waistcoat-wearing White Rabbit passing by, exclaiming that he is "late for an important date". Alice gives chase and follows him into a rabbit hole, and falls into a large furnished hole. Her dress catches her fall like a parachute and she floats gently down. She sees the White Rabbit disappear into a tiny door and tries to follow, but the door's talking knob advises her to alter her size using a mysterious bottle marked "Drink Me." The contents shrink her to a fraction of her normal size, but the door is locked and the key is out of reach. She then takes a bite of a cookie that says “Eat Me” and grows large enough to fill the entire room. She begins to weep large tears that flood the room. The doorknob then tells Alice to drink from the bottle again, which causes her to shrink once more. Alice falls into the bottle and passes through the door's keyhole and into Wonderland. She meets several strange characters including the Dodo and Tweedledee and Tweedledum who recount the tale of "The Walrus and the Carpenter".
Jafar, Grand Vizier to the Sultan of the fictional sultanate of Agrabah, attempts to retrieve a magical oil lamp containing a genie from the Cave of Wonders. He enlists a petty thief to enter the cave and retrieve it, whose attempt fails. Jafar and his parrot assistant, Iago, learn that only a "Diamond in the Rough" can enter the cave. Meanwhile, Jasmine, the Sultan's daughter, frustrated with her life in the palace, flees to Agrabah's marketplace. There she meets street rat Aladdin and his monkey pet, Abu, and the two begin to form a friendship. After Jafar orders Aladdin to be captured, Jasmine orders him to have him released but Jafar tricks her into thinking Aladdin was sentenced to death.
Charlie Bucket (Freddie Highmore) is a kind and loving boy living in poverty with his parents (Noah Taylor and Helena Bonham Carter) and four bedridden grandparents. They all rely on his father for income, employed at a toothpaste factory, responsible for putting the caps on the tubes. Down the street is Willy Wonka's (Johnny Depp) chocolate factory, which reopened after industrial espionage forced him into seclusion and to sack his employees. Charlie's Grandpa Joe (David Kelly) worked for Wonka before the termination.
Blue macaws Blu and Jewel, and their three children, are living happily in the city until Jewel realises that her children are becoming more like humans. Meanwhile, Blu's former owner, Linda Gunderson and her ornithologist husband, Tulio are on an expedition in the Amazon and eventually discover a quick-flying spix's macaw that loses one of its feathers. When word gets out about this through television, Jewel believes that they should go to the Amazon to help find the blue macaws. While the kids are ecstatic, Blu is uncertain, but is pressured into going along. Rafael, Nico and Pedro decide to come along. Luiz attempts to follow, but fails. Blu brings a fanny pack full of supplies, one of which he uses mostly is a GPS, much to Jewel's displeasure.
In the 1880s, an English couple and their infant son escape a burning ship, ending up on land near uncharted rainforests off the coast of Africa. The couple craft themselves a treehouse from their ship's wreckage, but are subsequently killed by Sabor, a rogue leopardess. Kala, a female gorilla who recently lost her own child to Sabor, hears the cries of the orphaned human infant and finds him in the ruined treehouse. Though she is attacked by Sabor, Kala and the baby manage to escape. Kala takes the baby back to the gorilla troop to raise as her own, an act of which her mate, Kerchak, disapproves. Kala raises the human child, naming him Tarzan. Though he befriends other gorillas in the troop and other animals, including the young female gorilla Terk and the paranoid male elephant Tantor, Tarzan finds himself unable to keep up with them, so he takes great efforts to improve himself. As a young man, Tarzan is able to kill Sabor with his crude spear and protect the troop, gaining Kerchak's reluctant respect.
During a benefit concert in Paris, France, David Seville (Jason Lee) is injured. Having to recuperate there, Dave asks his aunt (Kathryn Joosten) to look after the Chipmunks, Alvin (Justin Long), Simon (Matthew Gray Gubler) and Theodore (Jesse McCartney). Arrangements are also made for them to go to school at West Eastman High School. After another accident, the Chipmunks are left in the care of Toby (Zachary Levi), Jackie's grandson. Meanwhile, Ian Hawke (David Cross) lives in the basement of JETT Records. Three singing female chipmunks, Brittany (Christina Applegate), Jeanette (Anna Faris) and Eleanor (Amy Poehler), also known as The Chipettes, emerge and Ian hires them as plot to get back at the Chipmunks and revive his career.