Conceived by means of in vitro fertilization, Anna Fitzgerald (Abigail Breslin) was brought into the world as a savior sister at the informal suggestion of Kate's doctor, Dr. Chance (David Thornton) (a formal suggestion from the doctor would have been a violation of legal and medical ethics). As a genetic match for her older sister, Kate (Sofia Vassilieva), who suffers from acute promyelocytic leukemia, to donate compatible organs, blood and tissue in order to keep her sister alive. Her family members are introduced one by one, and each tells about how Kate's illness has affected them personally. When Kate turns 15, she goes into renal failure. Eleven-year-old Anna knows that she will be forced by her parents to donate one of her kidneys. She also realizes that she may not be able to live the life she will want to lead - she may be unable to cheerlead, play soccer, or be a mother. Anna tells her parents that she does not want any of this and proceeds to sue them for medical emancipation and the rights to her own body. Her domineering mother, Sara (Cameron Diaz), who leads an obsessive campaign to keep Kate alive, is indignant at Anna's decision when she receives the notice of court proceedings. Attorney Campbell Alexander (Alec Baldwin) agrees to work for Anna as her guardian ad litem, suing for partial termination of parental rights. It is later learned he agreed to take the case not for the notoriety, but because he suffers from epilepsy, and is genuinely sympathetic to her predicament.
Ann (Sarah Polley) is a hard-working 23-year-old mother with two small daughters, an unemployed husband (Scott Speedman), a mother (Deborah Harry) who sees her life as a failure, and a jailed father whom she has not seen in ten years. Her life changes dramatically when, during a medical checkup following a collapse, she is diagnosed with metastatic ovarian cancer and told she has only two months to live. Deciding not to tell anyone of her condition, using the cover of anemia, Ann makes a list of things to do before she dies. She decides to change her hair, record birthday messages for the girls for every year until they're 18, and tries to set up her husband with another woman. Feeling a longing to experience a life that was never available to her, she seeks out a man to experience how it feels to be in a sexual relationship with someone other than her husband. Her experiment ends up taking an emotional toll when she meets with a man named Lee, who ends up madly in love with her and is left heartbroken when Ann breaks up. He meets with her one last time and says that he will do anything to make her happy, taking care of her daughters and even finding her husband a job. She ends their relationship and never tells him that she is dying. At the end of the film Ann records a message to her husband telling him that she loves him and another one to Lee telling him the same. She then leaves all tapes she has recorded with her doctor asking him to deliver them after her death.
Life seems idyllic for Marisa (Jacinda Barrett) and her son, Jack (Tom Russell), until a poor performance at a school soccer match ends with Jack in hospital and Marisa trying to find her husband, David (Richard Roxburgh), who is interstate at a conference. In fact, David is planning to leave Marisa for his current mistress (Yvonne Strahovski), with his phone off and not a care in the world.
This film is a story of a sad romantic girl who has cancer. She tries to hide this from her lover. Her family is unaware of this problem. They care for her.
Lucas (Jacques Dutronc) inventeur génial d'un nouveau langage de programmation, apprend qu'il est atteint d'une maladie rare qui touche sa mémoire. Il rencontre Blanche (Sophie Marceau), une jeune femme désaxée qui le fascine. Célèbre pour ses séances d’hypnose où elle se dénude en révélant les secrets les plus noirs des spectateurs, elle vit sous la coupe d'une mère abusive et nymphomane. Ces deux êtres hors normes vivent alors une histoire d'amour passionnelle, mouvementée et tragique, où calembours et dialogues surréalistes tiennent lieu de mots d'amour.
Une famille du midi de la France, les Annequin. Noël, viticulteur, vit sur sa terre avec sa femme, Isabelle. Ses frères, établis à Aix-en-Provence, le dédaignent, une fois devenus de grands bourgeois. L'aîné, Hervé, est avocat ; Blaise, le cadet, est chirurgien, bien intégré dans la grande bourgeoisie locale. Isabelle, atteinte d'un cancer, supplie son mari de la tuer pour abréger ses souffrances. Noël s'exécute, la mort dans l'âme. Son acte accompli, il va s'en expliquer à ses frères. Par crainte du scandale, ceux-ci tentent d'étouffer l'affaire. Mais des lettres anonymes parviennent au procureur et Noël décide de se constituer prisonnier. Seule Martine, la fille de Blaise, juge avec sévérité l'égoïsme des siens et compatit à son drame. La famille veut plaider l'irresponsabilité et faire enfermer Noël pour maladie mentale. Un psychiatre se prête à la manœuvre.
Katie Price est atteinte d'une maladie appelée xeroderma pigmentosum (XP). Cette infirmité l'oblige à rester enfermée chez elle le jour car le soleil lui est néfaste ; elle n'est donc autorisée à sortir que la nuit. Son amie d'enfance, Morgan, passe la voir tous les soirs pour lui consacrer du temps. Depuis son enfance, elle est amoureuse de son voisin Charlie, qu'elle voit tous les jours depuis sa chambre, puisque ce dernier passe à côté de chez elle lorsqu'il va en cours ou à la piscine.
Vivian Bearing (Emma Thompson) is a professor of English literature known for her intense knowledge of metaphysical poetry, especially the Holy Sonnets of John Donne. Her life takes a turn when she is diagnosed with metastatic Stage IV ovarian cancer. Oncologist Harvey Kelekian prescribes various chemotherapy treatments to treat her disease, and as she suffers through the various side-effects (such as fever, chills, vomiting, and abdominal pain), she attempts to put everything in perspective. The story periodically flashes back to previous moments in her life, including her childhood, her graduate school studies, and her career prior to her diagnosis. During the course of the film, she continually breaks the fourth wall by looking into the camera and expressing her feelings.
K and Cream first meet each other in high school & both are orphans; K was abandoned by his mother after his father died of cancer who nevertheless left him a sizable sum of money, while Cream lost her entire family in a traffic accident. The two become soulmates and come to share a home, though K watches Cream switch from boyfriend to boyfriend as he keeps his own feelings for her to himself. Knowing that Cream's biggest fear is to be left alone, K keeps the fact that he has terminal cancer a secret, and instead he urges her to marry a kind and healthy man. When Cream announces that she is in love with affluent doctor Joo-hwan, K is left heartbroken, but is satisfied that she has met her ideal partner.
Detroit, Michigan, 1963: Bob Ivanovich is a young boy, who prays one night for a circus in his backyard the next day after school. After school the next day, he runs home eagerly, followed by his friends. To his disappointment, no circus awaits. Angrily, Bob retreats to the closet in his room, his personal retreat space.