Bob, chirurgien, arrière-petit-fils du Baron Frankenstein, a dissimulé son laboratoire dans le sous-sol de l’hôpital pour continuer les travaux de son illustre ancêtre. Avec son fidèle Iggy, il essaie de rassembler des morceaux de corps humains en vue de créer son propre “monstre”.
Stan Helsing (Steve Howey) is an underachieving employee at a video rental store named Schlockbuster whose personal mottos are "Don't get involved" and "Don't talk about it". His teen-aged boss Sully orders him to drop off a bag of movies to the mother of the store's owner or risk not having a job Monday morning. Despite his arguments, he agrees to the request and manages to get his friend Teddy (Kenan Thompson), his ex-girlfriend Nadine (Diora Baird) and ditsy blond massage therapist Mia (Desi Lydic) to take him there before they attend a Halloween party, even though it's on the other side of town.
A mad scientist (J. Carrol Naish) descended from
the original Dr. Frankenstein takes to murdering young women for experimentation in hopes of reviving his ancestor's creation, with help from his mute assistant Groton (Lon Chaney, Jr.). Dracula (played by Roger Engel under the pseudonym "Zandor Vorkov") comes to the scientist promising to revive Frankenstein's monster in return for a serum which will grant him immortality.
During the late 1880s, Dr Frankenstein’s evil granddaughter Maria has moved to the American West with her brother Rudolph, in order to use the prairie lightning storms in her experiments on immigrant children snatched from a dying town. Maria is very much in charge, killing the children and replacing their brains with artificial ones, intending to revive them as her slaves. Rudolph however, is reluctant to help his sister, but is too afraid of her to do otherwise. After a number of failures (owing to Rudolph secretly poisoning the victims as soon as his sister revives them), they are finding it increasingly difficult to hide the trail of bodies. Down the road, Mañuel Lopez and his wife Nina decide to leave town with their daughter Juanita because of the frequent disappearances, the latest of which is that of their son.
Big and burly African-American soldier Eddie Turner (Joe De Sue) stepped on a land mine while serving in Vietnam and lost both arms and legs. His physicist fiancee Doctor Winifred Walker (Ivory Stone) thinks she's found help for him in her white former teacher and colleague Doctor Stein (John Hart) who has recently won a Nobel Peace Prize for "solving the DNA genetic code".
After Alan Jones is savagely beaten by a street gang, he ends up at the lab of mad scientist Dr. Tanner Finski and his assistant Igor, a child genius. There, Jones discovers that he is the key to an experiment that involves Frankenstein's monster. When the experiment goes wrong, Finski sends Jones and Igor back in time to the American Civil War, where an interdimensional portal has allowed an army of monsters to converge.
Moira Frankenstein (Lina Romay), la fille du défunt professeur, découvre la "déesse" (Michelle Bauer), une créature féminine créée par son père. Fascinée, elle n'a plus qu'une idée en tête : trouver de jeunes filles pour contenter la créature.
Castle Frankenstein has been empty for years and the local council is planning to repossess it, when the Frankenstein family return, seeking to find hidden treasure, and to re-animate the Frankenstein monster.
When a hot air balloon crashes on a remote and uncharted island, the four balloonists and their dog Melvin are captured by a pair of drunken old pirates who take them to the hilltop laboratory home of Dr. Frankenstein's modern-day descendant Sheila Frankenstein (Katherine Victor) who is carrying on the family tradition by turning shipwrecked sailors into pre-programmed bloodless, black-garbed zombies who must wear sunglasses to protect their weird white eyes from light.
After Baron Henry von Frankenstein creates a bride his monster, he decides to make arrangements for a lavish wedding at the Transylvania Astoria Hotel. Many monsters are invited to the wedding including Count Dracula and his son, Ron Chanley the Werewolf, the Mummy, Dr. Jekyll and Mr. Hyde, the Invisible Man and his family, and the Creature from the Black Lagoon. Once the wedding guests arrive, they terrify guests and staff. Frankenstein's assistant Igor is jealous of the monster and wants the bride for his own. So Igor plots to steal her which doesn't go according to plan when the bride ends up snatched up by a Pterodactyl and lands in the clutches of a giant gorilla named Modzoola.
I Was A Teenage Frankenstein's Roommate is the story of Hiram Belmore (Patrick Casey) and his attempt to create life and therefore win the school science fair. Peggy (Sarah K. Bizek) and her boyfriend Dwight (Nick Stukas) are house-sitting for Peggy's professor. Dwight's friend Hiram hijacks the house and uses it in his experiment to create his Frankenstein's monster, which he names Monster (Worm Miller). His class rival Lionel Kerr (Sean Hall) is trying to prevent this and win the science fair himself, while Clerval (Jack Shreck) co-opts control of a religious sect to make things turn out in his favor and wackiness ensues.