In 2005, elderly Daisy Fuller is on her deathbed in a New Orleans hospital; she asks her daughter, Caroline, to read aloud from the diary of Benjamin Button. From the reading, we learn that on the evening of November 11, 1918, a boy is born with the appearance and physical maladies of an elderly man. The baby's mother died after giving birth, and the father, Thomas Button, abandons the infant on the porch of a nursing home. Queenie and Mr. "Tizzy" Weathers, workers at the nursing home, find the baby, and Queenie decides to care of him as her own.
Gaylord "Greg" Focker (Ben Stiller) is a nurse living in Chicago, who intends to propose to his girlfriend Pam Byrnes (Teri Polo), a schoolteacher. His plan is disrupted when Pam's sister Debbie becomes engaged and he finds out that Debbie's fiance, Dr. Robert "Bob" Banks had asked Pam's father for permission before proposing. Greg and Pam travel to Pam's parents' house in Oyster Bay, Long Island to attend the wedding. Greg hopes to propose to Pam in front of her family after receiving her father's permission, but this plan is put on hold when the airline loses his luggage, including the engagement ring.
Andrea "Andy" Sachs (Anne Hathaway) is an aspiring journalist fresh out of Northwestern University. Despite her ridicule for the shallowness of the fashion industry, she lands a job "a million girls would kill for," junior personal assistant to Miranda Priestly (Meryl Streep), the icy editor-in-chief of Runway fashion magazine. Andy plans to put up with Miranda's bizarre and humiliating treatment for one year in hopes of getting a job as a reporter or writer somewhere else.
In 1482 Paris, Clopin, a gypsy puppeteer, narrates the origin of the titular hunchback. A group of gypsies sneak illegally into Paris, but are ambushed by Judge Claude Frollo, the minister of justice. A gypsy woman in the group attempts to flee with her deformed baby, but Frollo chases and kills her outside Notre Dame. He tries to kill the baby as well, but the cathedral's archdeacon intervenes and accuses Frollo of murdering an innocent woman. To atone for his sin, Frollo reluctantly agrees to raise the deformed child in Notre Dame as his son, naming him Quasimodo.
Abby Richter (Katherine Heigl) is a morning show TV producer in Sacramento, California. Abby firmly believes in true love and is a big supporter of complex self-help books such as Chicken Soup for the Soul and Men Are from Mars, Women Are from Venus. Coming home from a disastrous date, she happens to see a segment of a local television show, The Ugly Truth, featuring Mike Chadway (Gerard Butler), whose cynicism about relationships prompts Abby to call in to argue with him on-air. The next day, she discovers the TV station is threatening to cancel her show because of its poor ratings. The station owner has hired Mike to do a segment on her show.
Dan Gallagher (Michael Douglas) is a successful, happily married New York attorney living in Manhattan when he meets Alexandra "Alex" Forrest (Glenn Close), an editor for a publishing company, through business. While his wife, Beth (Anne Archer), and daughter, Ellen (Ellen Hamilton Latzen), are out of town for the weekend, he has an affair with Alex. Though he thought it was understood to be a simple fling, she begins clinging to him.
Margaret Tate is an executive editor in chief of a book publishing company. After learning she is about to be deported to Canada because she violated the terms of her work visa, she persuades her assistant, Andrew Paxton, to marry her. She reminds Andrew that if she's deported, the work he put in as her assistant will be lost, and he'll be set back in his dream to become an editor. Mr. Gilbertson, a U.S. immigration agent, informs them that he suspects they are committing fraud to avoid Margaret's deportation. Gilbertson tells them that they'll be asked questions about each other separately. If their answers don't match, Margaret will be deported to Canada permanently and Andrew will be convicted of a felony punishable by a $250,000 fine and five years in prison. Andrew insists that Margaret make him an editor after their marriage and publish the book he's been recommending to her. Margaret agrees.
In 1947, John Nash (Crowe) arrives at Princeton University. He is co-recipient, with Martin Hansen (Lucas), of the prestigious Carnegie Scholarship for mathematics. At a reception, he meets a group of other promising math and science graduate students, Richard Sol (Goldberg), Ainsley (Jason Gray-Stanford), and Bender (Rapp). He also meets his roommate Charles Herman (Bettany), a literature student.
Melvin Udall is a misanthrope who works at home as a best-selling novelist in New York City. He suffers from obsessive-compulsive disorder which, paired with his misanthropy, alienates nearly everyone with whom he interacts. He avoids stepping on sidewalk cracks while walking through the city due to a superstition of bad luck, and eats breakfast at the same table in the same restaurant every day using disposable plastic utensils he brings with him due to his pathological mysophobia. He takes an interest in his waitress, Carol Connelly, the only server at the restaurant who can tolerate his behavior.
Gaylord "Greg" Focker (Stiller) is preparing to celebrate his twins' fifth birthday party. Things seem to go awry when Greg's father-in-law Jack Byrnes (De Niro) visits. Recently, Jack has been diagnosed with a heart condition and become embittered by his daughter Debbie's divorce from her husband, Bob (whose marriage was the social event in the first film and how Jack and Greg met), for cheating on her with a nurse. Jack's plan was originally to name Bob as his successor as head of the Byrnes family, but decides to pass the role to Greg, naming him "The Godfocker." Despite Greg reluctantly accepting the role, Jack begins to suspect Greg of infidelity when he sees him with a drug representative, Andi Garcia (Alba), who openly flirts with him, and the presence of Sustengo erection pills in Greg's house, which prompts Jack to think Greg is no longer sexually attracted to his wife, Pam (Polo). Furthermore, Jack starts to doubt Greg's ability to provide for his family when he appears reluctant to send his children to a private school.
Maggie Carpenter (Julia Roberts) is a spirited and attractive young woman who has had a number of unsuccessful relationships. Maggie, nervous of being married, has left a trail of fiancés. She's left three men waiting for her at the altar on their wedding day (all of which are caught on tape), receiving tabloid fame and the dubious nickname "The Runaway Bride".
Hazel Grace Lancaster (Shailene Woodley) is an intelligent and witty teenager living in Indianapolis, who has terminal thyroid cancer that has since spread to her lungs. Believing she is depressed, Hazel's mother Frannie (Laura Dern) urges her to attend a weekly cancer patient support group to help her make friends who are going through the same thing.
L’Avalon, un vaisseau spatial de la compagnie Homestead, se dirige vers la planète Homestead II. À son bord se trouvent 5000 passagers dont 258 membres d’équipage dont le but est de fonder une colonie spatiale, alors que la Terre est surpeuplée. Le voyage doit durer 120 ans et tous les voyageurs sont placés en biostase dans des capsules individuelles. Mais après 30 ans, l'Avalon traverse un champ d'astéroïdes dont l'un d'eux trop gros pour le bouclier du vaisseau créé plusieurs avaries, qui se propagent à l'une des capsules d'hibernation et déclenchent le processus de réveil de son occupant, Jim Preston, un mécatronicien.
Julianne Potter (Julia Roberts), a 27-year-old New York restaurant critic, receives a call from her longtime friend Michael O'Neal (Dermot Mulroney). In college, the two made an agreement that if neither of them were married by the time they turned 28, they would marry each other. Three weeks before her 28th birthday, Michael tells her that in four days, he will marry Kimmy Wallace (Cameron Diaz), a 20-year-old University of Chicago student from a wealthy family.
The story begins five days after the assault on the Abnegation faction by Erudite leader Jeanine's mind-controlled Dauntless soldiers. Dauntless leader Eric and his platoon search through the wreckage of Abnegation for a box of unknown origin that contains the symbols for each faction. They recover the box and take it to Erudite. Jeanine claims it contains data from the city's founders and the means to end the Divergence problem–the issue of individuals having the qualities of multiple factions. Only a Divergent can open the box, so she orders all Divergents hunted down and captured.