L'action ne se déroule pas au XIX siècle, mais vers la fin des années 1960. Dans son laboratoire, le Dr. Tabani pense avoir découvert la formule de la vie éternelle. Mais l'expérience le transforme en vampire. À la nuit tombée, Tabani part s’abreuver du sang de ses victimes, seul élixir ayant le pouvoir de le rendre éternel.
Count Dracula (Alexander D'Arcy) and his vampire wife (Paula Raymond), hiding behind the pseudonyms of Count and Countess Townsend, lure girls to their castle in the Arizona desert to be drained of blood by their butler George (John Carradine), who then mixes real bloody marys for the couple. Then the real owners of the castle show up, along with Johnny, who is a serial killer or a werewolf depending on which version you watch. The owners refuse to sell, so Dracula wants to force them to sell. In a final confrontation, the vampires are forced to stand in the sunlight and dissolve.
A mad scientist (J. Carrol Naish) descended from
the original Dr. Frankenstein takes to murdering young women for experimentation in hopes of reviving his ancestor's creation, with help from his mute assistant Groton (Lon Chaney, Jr.). Dracula (played by Roger Engel under the pseudonym "Zandor Vorkov") comes to the scientist promising to revive Frankenstein's monster in return for a serum which will grant him immortality.
The Joker and the Penguin break out of Arkham Asylum and race each other to find a stash of stolen money hidden within a crypt in Gotham Cemetery after an inmate, who had hidden it, told them about it. The Joker is quickly intercepted by the Batman and is electrocuted when he falls into a river by his super-charged joy buzzers while the Penguin takes the opportunity to enter the cemetery himself. While searching through a crypt, the Penguin accidentally cuts his hand while using his umbrella-sword to open a coffin he hopes contains the money, finding a body instead. Blood from his hand drips on the corpse's heart, which brings it to life; it is none other than the vampire lord Count Dracula, his body having been moved from Transylvania to Gotham City after his "death." After attacking and turning a watchman at the cemetery into a vampire, Dracula hypnotizes the Penguin into becoming his non-vampiric servant so that he may lead him through Gotham to feed and guard his coffin during the day while he regains his strength.
After Baron Henry von Frankenstein creates a bride his monster, he decides to make arrangements for a lavish wedding at the Transylvania Astoria Hotel. Many monsters are invited to the wedding including Count Dracula and his son, Ron Chanley the Werewolf, the Mummy, Dr. Jekyll and Mr. Hyde, the Invisible Man and his family, and the Creature from the Black Lagoon. Once the wedding guests arrive, they terrify guests and staff. Frankenstein's assistant Igor is jealous of the monster and wants the bride for his own. So Igor plots to steal her which doesn't go according to plan when the bride ends up snatched up by a Pterodactyl and lands in the clutches of a giant gorilla named Modzoola.
McGregor, un comédien spécialisé dans l'horreur, ne veut plus tourner que dans des films romantiques. Son producteur tente de lui faire entendre raison, et envoie deux scénaristes gaffeurs et deux actrices pour le convaincre.
Count Dracula is an old vampire who, because of his advanced age, is forced to host tours of his castle to get new victims. In an attempt to revive his long-lost love, Vampira, Dracula sets out to collect blood from the bevy of Playboy Playmates living at his castle. However, one of the Playmates whose blood is drained is black, turning the revived Vampira into a black woman.
Renfield, a solicitor, makes a journey into Transylvania via stagecoach. He mentions his destination, Castle Dracula, to the locals who react with alarm. They tell him Count Dracula is a vampire and when he doesn't believe them, one insists he wear a cross. When he arrives at the Castle, the Count bids him welcome. After drinking drugged wine, Renfield drops the cross and is bitten.
Baron Boris von Frankenstein (voiced by Boris Karloff) achieves his ultimate ambition, the secret of total destruction. Having perfected and tested the formula, he sends out messenger bats to summon all monsters to the Isle of Evil in the Caribbean Sea. The Baron intends to inform them of his discovery and also to reveal his imminent retirement as head of the "Worldwide Organization of Monsters". Besides Frankenstein's Monster (referred to as "Fang") and the Monster's more intelligent mate (voiced by Phyllis Diller) who live in the island castle with Boris, the invites also include Count Dracula, the Mummy, Quasimodo (referred to as "The Hunchback of Notre Dame"), the Werewolf, The Invisible Man, Dr. Jekyll and Mr. Hyde, and the Creature from the Black Lagoon (referred to as the "Creature").
"Bistritz, Hungary May 1897": natives in Transylvania seem afraid when they learn solicitor Jonathan Harker is going to Castle Dracula. Jonathan shows up, and finds the Count abrupt and impatient to get things done. He reacts very strongly to a photograph of Harker's fiancée Mina and her best friend Lucy. After rescuing Harker from the Brides, he forces Harker to write a letter saying that he will be staying in Transylvania for a month. Harker climbs down the castle wall and finds Dracula's coffin, but is attacked and knocked out by one of Dracula's gypsy servants before he can stake Dracula. They later throw him in the lower levels of the crypt, where the Brides attack Harker.
Lucy Westenra's sister Mina bids farewell to her fiancé Jonathan Harker, who is leaving for a business trip. Harker, a solicitor, is travelling to Count Dracula's castle in Transylvania to expedite his purchase of Carfax Abbey and other properties in England.
Transylvania, 1979: Hard times have fallen upon the House of Dracula, and to help pay the taxes on the ancestral castle it has been converted into the Hotel Transylvania. The manager of the hotel is the beautiful and sensuous Nocturna (Nai Bonet), granddaughter of the original Count (John Carradine) who still resides in the crypt deep in the sub-basement of the establishment.
While walking her guard rounds in the country, 17-year-old Doris Lang, the daughter of a deceased werewolf hunter, is attacked by Count Magnus Lee, a 10,000-year-old, long-lost vampire lord (also known as a Noble), who intends to make her his new vampire bride.
Vlad Tepes, the Prince of Darkness, resurfaces in Los Angeles with a new look, new life and new love. But with the new life comes an old nemesis who has waited an eternity to settle the score.