John Connor has been living off the grid in Los Angeles in the years following the death of his mother, Sarah, from leukemia. Although Judgment Day did not occur on August 29, 1997, as expected, John still believes that a war between humans and the machines will occur. Unable to locate John in the past, Skynet sends a new model of the Terminator called the T-X back to July 24, 2004 to kill other members of the Human Resistance. The T-X is more advanced than previous Terminators, and has an endoskeleton with built-in weaponry, a liquid metal exterior similar to the T-1000, and the ability to reprogram other machines. Unlike previous Terminators, its standard appearance is female. The Resistance sends a reprogrammed Terminator (T-850 - Model 101) back in time to protect the T-X's targets including John and his future wife, Kate Brewster.
In 1989, Kevin Flynn, software engineer and the CEO of ENCOM International, disappears. Twenty years later, his son Sam, now ENCOM's primary shareholder, takes little interest in the company beyond playing an annual prank on its board of directors.
The FBI responds to a brief computer outage at their Cyber-Security Division by tracing down top computer hackers, finding several of them have been killed. Taking others into protective custody, the FBI asks New York City Police Department detective John McClane (Bruce Willis) to bring in Matthew "Matt" Farrell (Justin Long), one of the targeted hackers. McClane finally arrives just in time to prevent Farrell from being killed by assassins working for Mai Linh (Maggie Q), a mysterious cyber-terrorist who works for her boss and love interest, Thomas Gabriel (Timothy Olyphant).
In a restaurant in Los Angeles, a man discusses the 1975 film Dog Day Afternoon before walking off, with numerous SWAT officers pointing guns at him and a dishevelled man following him out. They walk to a nearby building with gunmen and hostages strapped with bombs and ball-bearings. One of the gunmen is killed by a sniper; when the hostage is forcibly taken away, the explosives detonate via a proximity trigger, killing her and others. The film then flashes back four days.
In 1969, students Martin Brice and Cosmo are sneakers who hack into computer networks using university equipment, to redistribute conservative funds to various liberal causes. The police burst in and arrest Cosmo while Martin is out getting pizza, and Martin becomes a fugitive.
Dr. Will Caster (Johnny Depp) is a scientist who researches the nature of death and sentience, including artificial intelligence. He and his team work to create a sentient computer; he predicts that such a computer will create a technological singularity, or in his words "Transcendence". His wife Evelyn (Rebecca Hall) is also a scientist and helps him with his work.
The film opens with Jack Stanfield (Harrison Ford) leaving his house, loving wife Beth (Virginia Madsen) and two children, to his job at Landrock Pacific Bank in downtown Seattle. The day goes smoothly until Jack is visited by a collection agency, claiming that he owes $95,000 in debts to their online gambling site. He trusts a colleague to take care of it (as he is convinced of some form of identity theft, which is later found out to be true and used to later set up Jack with a motive for robbing the bank) and goes out for dinner with colleague Harry Romano (Robert Forster) and potential employer, Bill Cox (Paul Bettany). After the meal, Harry leaves in a taxi and Jack gets in his car. Unexpectedly, Cox follows him into the back seat. Cox then goes on to tell Jack that his family is being held hostage at their home to ensure Jack's cooperation. He then points a gun to Jack's head and forces him to drive home.
During a surprise drill of a nuclear attack, many United States Air Force Strategic Missile Wing missileers prove unwilling to turn a required key to launch a missile strike. Such refusals convince John McKittrick (Dabney Coleman) and other systems engineers at NORAD that missile launch control centers must be automated, without human intervention. Control is given to a NORAD supercomputer, WOPR (War Operation Plan Response), programmed to continuously run military simulations and learn over time.
Dans un futur proche, aux Etats-Unis, la jeune Mae Holland mène une vie banale ; elle est secrétaire dans une petite entreprise, vit encore chez ses parents Bonnie et Vinnie, n'a pas de petit ami et repousse les avances de son ami Mercer. L'unique activité solitaire qu'elle s'offre pour décompresser et se ressourcer est le kayak. Un jour, son amie Annie Allerton aide Mae à être embauchée dans son entreprise, Le Cercle, le plus important groupe de services technologiques du monde. Cette formidable opportunité lui permet, entre autres, de faire enfin bénéficier son père, atteint de sclérose en plaques, de soins adaptés. Alors que son implication au sein de l'entreprise ne cesse d'augmenter, ses patrons Eamon Bailey et Tom Stenton l'encouragent à participer à une expérience révolutionnaire dont le but est d'être filmée en permanence par une mini-caméra connectée SeeChange. Désormais, les choix de Mae impactent la vie de ses proches, de ses amis et de toute l'humanité, en bousculant les limites de la vie privée, de l'éthique et des libertés individuelles.
Kevin Flynn (Jeff Bridges) is a software engineer, formerly employed by the computer corporation ENCOM, who now runs an arcade bar called Flynn's. He wrote several video games, but another ENCOM engineer, Ed Dillinger (David Warner), stole them and passed them off as his own, earning himself a series of promotions until reaching Senior Executive VP. Having left the company, Flynn attempts to obtain evidence of Dillinger's actions by hacking the ENCOM mainframe, but is repeatedly stopped by the Master Control Program (MCP), an artificial intelligence written by Dillinger. However, since its inception the MCP has become power-hungry, illegally appropriating business and even government programs and absorbing them to increase its own capacities; it informs Dillinger of its plans to subjugate The Pentagon and the Kremlin, and expresses interest in China with its request for Chinese-translation programs, blackmailing Dillinger into compliance with records of his theft of the games.
Kenji Koiso (Ryunosuke Kamiki) is a young student at Kuonji High School with a gift in mathematics and a part-time moderator in the massive computer-simulated virtual reality world OZ along with his friend Takashi Sakuma (Takahiro Yokokawa).
At a nuclear plant in Chai Wan, Hong Kong, a hacker causes the coolant pumps to overheat and explode. Not long after in Chicago, the Mercantile Trade Exchange gets hacked, causing soy futures to rise. The Chinese government and the FBI determine that the hack was caused by a Remote Access Tool (RAT). A military officer in China's cyber warfare unit, Captain Chen Dawai (Leehom Wang), is tasked to find the people responsible for the attacks, and enlists the aid of his sister Chen Lien (Tang Wei), a networking engineer. He meets with FBI Agent Carol Barrett (Viola Davis) in Los Angeles and reveals the code in the RAT was written by himself and Nicholas Hathaway (Chris Hemsworth), his college roommate, in their school days years before Hathaway was sent to prison for an unrelated hack. Dawai asks that the FBI arrange for Hathaway to be released from prison, where he is serving a sentence for computer crimes. Hathaway is offered temporary release in exchange for his services.
Benjamin Engel, un pirate informatique de Berlin, est assis dans une salle d'interrogatoire. L’officier en charge dit à Hanne Lindberg, chef de la division Cyber d’Europol, que Benjamin avait demandé à subir l’interrogatoire. Benjamin affirme avoir des informations sur FRI3NDS, un groupe de pirate informatique notoire de quatre membres connecté à la cyber-mafia russe, et sur MRX, une figure célèbre sur le Darknet. II réclame l'attention de Hanne avant de dévoiler ses informations.