Six months after the events of the first film, Neo and Trinity are now lovers. Morpheus receives a message from Captain Niobe of the Logos calling an emergency meeting of all of Zion's ships. Zion has confirmed the last transmission of the Osiris: an army of Sentinels is tunneling towards Zion and will reach it within 72 hours. Commander Lock orders all ships to return to Zion to prepare for the onslaught, but Morpheus asks one ship to remain in order to contact the Oracle. The Caduceus receives a message from the Oracle, and the Nebuchadnezzar ventures out so Neo can contact her. One of the Caduceus crew, Bane, encounters Agent Smith, who takes over Bane's avatar. Smith then uses this avatar to leave the Matrix, gaining control of Bane's real body.
Ethan Hunt (Tom Cruise), while vacationing, is alerted by the IMF that someone has used his identity to assist Russian bio-chemical expert Dr. Vladimir Nekhorvich (Rade Serbedzija) of Biocyte Pharmaceuticals to enter the United States, only to kill him in a subsequent plane crash. Nekhorvich, an old friend of Ethan, had forewarned the IMF of his arrival, planning to deliver a new bioweapon, Chimera, and its cure, Bellerophon, both of which he was forced to develop by Biocyte, into the IMF's hands. With his death, IMF is worried that the virus is out in the open, believing that rogue IMF agent Sean Ambrose (Dougray Scott) is responsible. IMF assigns Ethan to recover it. Ethan is told that he can use two members of his team to help him, but the third person to help him must be Nyah Nordoff-Hall (Thandie Newton), a professional thief presently operating in Seville, Spain, as she will be able to get close to Ambrose, being an ex-girlfriend.
In 1995, John Connor is ten years old and living in Los Angeles with foster parents. His mother Sarah Connor had been preparing him throughout his childhood for his future role as the leader of the Human Resistance against Skynet, but was arrested after attempting to bomb a computer factory and imprisoned at a mental hospital under the supervision of Dr. Silberman. Skynet sends a new Terminator, designated as T-1000, back in time to kill John. The T-1000 is an advanced prototype composed of a mimetic polyalloy that allows it to take on the shape and appearance of almost anything it touches, and transform parts of its anatomy into knives and other stabbing weapons. The T-1000 arrives under a freeway, kills a policeman and assumes his identity. Meanwhile, the future John Connor has sent back a reprogrammed T-800 (Model 101) Terminator to protect his younger self.
In 1912, 13-year-old Indiana Jones is horseback riding with his Boy Scout troop in Moab, Utah. While scouting caves, Indy discovers a group of grave robbers who have found a golden crucifix belonging to Coronado and steals it from them, hoping to donate it to a museum. The men give chase through a passing circus train, leaving Indy with a bloody cut across his chin from a bullwhip and new phobia of snakes. Indy escapes, but the local sheriff makes him return the crucifix. Impressed with Indy's bravery, the leader of the robbers gives Indy his fedora.
In 2035, humanoid robots serve humanity. Humans are protected from the robots by the Three Laws of Robotics. Del Spooner (Smith), a Chicago police detective, distrusts robots after a car crash ended in a robot rescuing him and leaving a preteen girl to die, based on statistical likelihood of survival. After the accident, Spooner received a cybernetic left arm, lung, and ribs, personally implanted by the co-founder of U.S. Robots and Mechanical Men (USR), Dr. Alfred Lanning (Cromwell), who Spooner has befriended.
MI6 sends James Bond, agent 007, into the field to spy on a terrorist arms bazaar on the Russian border. Via television, MI6 and the Royal Navy identify several wanted men, including the American "techno-terrorist" Henry Gupta, who is buying a GPS encoder made by the US military. Despite M's insistence to let 007 finish his reconnaissance, British Admiral Roebuck launches a missile attack on the arms bazaar. Bond then discovers two Soviet nuclear torpedoes mounted on an L-39 Albatros, and as the missile is too far along to be aborted, 007 hijacks the L-39 and flies away seconds before the bazaar is struck. Amidst the confusion, Gupta escapes with the encoder.
The film opens with Lara Croft (Angelina Jolie) in an Egyptian tomb, seeking a diamond at one end of a chamber. As she approaches she is attacked by a large robot. After an intense chase and battle, she disables it by ripping out its motivational circuits. She takes the diamond, which is revealed to be a memory card labeled "Lara's Party Mix", and inserts it into a laptop computer inside the robot, whereupon it plays music. Now it is revealed that the scene took place in a practice arena in her home, and that her assistant Bryce (Noah Taylor) programmed the robot, SIMON, to challenge her in combat.
Doug Madsen (Tim Allen), Woody Stevens (John Travolta), Bobby Davis (Martin Lawrence), and Dudley Frank (William H. Macy) are four middle-aged suburban men living in a Cincinnati area suburb who find themselves frustrated with the pace of daily life and lack of adventure. Doug is a dentist who has trouble relating to his son Billy (Dominic Janes), Dudley is a single clumsy computer programmer who is afraid to talk to women. Bobby is a henpecked plumber whose wife has made him return to work after having taken a year off to unsuccessfully write a book, and Woody is a rich lawyer married to a supermodel. They find escape from their lives on weekends by riding motorcycles together pretending to be a biker gang called the "Wild Hogs".
The Devil, Mephistopheles, sends his bounty hunter of the damned, the Ghost Rider, to retrieve the contract of San Venganza for control of a thousand corrupt souls. Seeing that the contract would give Mephistopheles the power to bring Hell on Earth, the Rider refuses to give him the contract.
Johnny English is an inept MI7 agent with dreams of being their most trusted employee. After Agent One dies in a submarine accident (courtesy of English making a mistake on checking the submarine hatch code), the remaining agents are assassinated via a bombing at Agent One’s funeral (again courtesy of English's incompetence at security), leaving English as the lone survivor. English is assigned to follow a plot to steal the Crown Jewels, which are on display at the Tower of London. At the display, English is head of security, and meets the mysterious Lorna Campbell. The power is cut, and the jewels are stolen. During the chaos, English knocks out a security guard in the process and fights the "assailant" (himself). He later makes up a false description of the assailant to Pegasus. English and his assistant Angus Bough find the jewels were removed via a hole dug beneath their display case. The two follow a tunnel, confronting the two thieves Klaus Vendetta and Dieter Klein. The two escape in a hearse, with English trying to pursue them, but mistakes another hearse for the escape vehicle, crashing a funeral until Bough comes to his aid.
On Santorini island, Greece, a wedding is interrupted by a strong earthquake. The earthquake uncovers the Luna Temple, built by Alexander the Great to house his most prized treasures. Among these treasures is a glowing orb with a pattern resembling a code etched into it. Lara (Angelina Jolie) finds this orb; but it is stolen by the crime lord Chen Lo (Simon Yam). Lara only just manages to escape with a strange medallion, while her two companions are killed by Chen's men.
Nick Conklin is a New York City police officer facing possible criminal charges; Internal Affairs believes Nick was involved with his partner who was caught taking criminal money in a corruption scandal. Nick is divorced from his wife, who has custody of their two children. Nick also has financial difficulties.
A French priest named Moreau warns the monks of a monastery about an impending attack by the devil's forces to obtain a boy named Danny. The monastery falls under attack; Moreau tries to help the boy and his mother Nadya escape, but the distrusting mother shoots at Moreau and flees with her son. Moreau manages to distract the men chasing Danny and Nadya, but nearly dies in the process and loses them. He believes that only the Ghost Rider is capable of protecting the boy. He finds the Rider and seeks his help.
In the near future, Michael Jennings (Affleck) is a reverse engineer; he analyzes his clients' competitors' technology and recreates it, often adding improvements beyond the original specifications. To protect his clients' intellectual property and himself, Jennings, with the aid of his friend Shorty (Giamatti), undertakes a memory wipe to remove knowledge of his engineering.
On October 30, Devil's Night in Detroit, Sergeant Albrecht is at the scene of a crime where Shelly Webster has been beaten and raped, and her fiancé Eric Draven then died on the street outside, having been stabbed, shot, and thrown out of the window. The couple were to be married the following day, on Halloween. As he leaves for the hospital with Shelly, Albrecht meets a young girl, Sarah, who says that she is their friend, and that they take care of her. Albrecht tells her that Shelly is dying.