On the run from their enemy, the planet-destroying Gorg, the Boov find Earth a suitable place to call "home". Led by Captain Smek (Steve Martin), they commence their "friendly" invasion of the planet, relocating the humans, whom the Boov deem as simple and backwards, to other parts of the planet while the Boov inhabit their homes in a quick and bloodless conquest. One of the Boov, named Oh (Jim Parsons), is a more excited, freethinking member of the species, who decides to invite the Boov to his apartment for a housewarming party, despite the race's antipathy towards him. Not far from Oh is a preteen girl named Tip (Rihanna), who drives away through her home city to find her mother Lucy (Jennifer Lopez) after being separated from her during the invasion, leaving her with only her calico cat Pig and fueling her hatred for the Boov.
Minions are small, yellow creatures who have existed since the beginning of time, evolving from single-celled organisms into beings who exist only to serve history's most villainous masters. They find great masters—including a T-Rex, a caveman, an Egyptian pharaoh, Dracula, and Napoleon,—but after accidentally killing nearly all of them with their incompetence, they decide to isolate themselves from the world and start a new life in Antarctica. By 1968, the lack of a master to serve drives them into depression, so Kevin, one fearless Minion, plans to find a new one for them by going back out into the world. Stuart—a bored, teenaged minion who is obsessed with guitars—joins him reluctantly, as does an over-enthusiastic Bob, whom Kevin only chooses because of no one else willing to volunteer.
Five years after the first film, Lou Dorchen, Nick Webber, and Jacob have led their lives to fame, but each struggling with their self-esteem. Lou brags his success through time travel to his employee Brad, while Nick's wife Courtney complains about Nick going wherever he wants, whereas Jacob shows hatred for Lou. Lou hosts a party where he declines an offer by old schoolmate Gary Winkle to buy land, and forcing Jacob to act as a butler. However, Lou is shot in the penis, urging Jacob and Nick to take him to the hot tub time machine, in hopes to find and stop Lou's killer.
In 1989, scientist Hank Pym resigns from S.H.I.E.L.D. after discovering their attempt to replicate his Ant-Man shrinking technology. Believing the technology is dangerous, Pym vows to hide it as long as he lives. In the present day, Pym's estranged daughter, Hope van Dyne, and former protégé, Darren Cross, have forced him out of his own company. Cross is close to perfecting a shrinking suit of his own, the Yellowjacket, which horrifies Pym.
In response to a record high crime rate in Johannesburg, the South African government purchases a squadron of state-of-the-art, armour-plated attack robots from weapons manufacturer Tetravaal, developed by Deon Wilson. A competing project is the remotely controlled MOOSE, developed by soldier-turned-engineer Vincent Moore. Deon is praised for Tetravaal's success but Vincent grows jealous when the police are unwilling to give his heavy weapons platform equal attention. At home, Deon creates a prototype artificial intelligence that mimics a human mind to the point of feeling emotions and having opinions, but Tetravaal CEO Michelle Bradley refuses to let him test the A.I. on a police robot. Undeterred, Deon steals a recently damaged robot before it is destroyed and puts it in his van, along with the "guard key" needed to update the robot's software. On his way home, he is kidnapped by a group of gangsters, Ninja, Yolandi, and Amerika, who threaten to kill him unless he reprograms a police robot to fight for them. Deon installs the new software into the damaged robot, which responds with childlike terror upon powering up. Deon and Yolandi calm the robot, teaching it words and naming it "Chappie". Despite Deon wanting to stay with the robot, Ninja forces him out of their hideout.
Sometime in the early 1980s, Miami-Dade Police Department detective Kung Fury and his partner Dragon apprehend a red ninja in a back alley, but Dragon is sliced in half by the ninja while Kung Fury is suddenly struck by lightning and bitten by a cobra, giving him extraordinary kung fu powers that enable him to defeat his foe. Years later in 1985, after defeating a rogue arcade machine robot, Kung Fury quits the force when he is assigned to partner with Triceracop, fearing that he would lose another partner in the line of duty. Meanwhile, Adolf Hitler, a.k.a. "Kung Führer", enters the timeline and remotely guns down the police chief and attacks the precinct through a mobile phone. Intent to avenge the chief, Kung Fury has computer whiz Hackerman send him back in time to kill Hitler in Nazi Germany. A glitch in the system, however, sends him back into the Viking Age. After Kung Fury meets the Viking valkyries Barbarianna and Katana, the Norse god Thor sends him to Nazi Germany for him to finish his job.
Neil Clarke (Simon Pegg) is a disillusioned schoolteacher, who suddenly finds and uses the ability to do anything he wants, a challenge bestowed upon him by a group of power-crazed aliens (John Cleese, Terry Gilliam, Eric Idle, Terry Jones and Michael Palin) watching him from space. As he struggles to deal with these new found powers and the events that subsequently arise, he calls upon his loyal canine companion and best friend Dennis (Robin Williams) to help him along the way.
In the summer of 1982, Sam Brenner and Will Cooper are thirteen-year-olds who love playing in the local arcade. Brenner enters an arcade game world championships. At the event, the MC tells that a time capsule will be launched into space containing a videocassette that includes scenes from the championships. Brenner and Cooper meet Ludlow Lamonsoff, a child who's in love with Lady Lisa, the main character of the game Dojo Quest. Brenner succeeds in every game, but finally loses to Eddie Plant in Donkey Kong.
The movie opens with Daphne Blake trying to pass her driver's test and get her license. She is in the Mystery Machine. Velma Dinkley tells her she can do it, yet despite the encouragements, Daphne crashes the van into a tree. Later she and Velma win a lottery that takes people into space. The two girls soon find themselves going into space along with Billionaire Sly Baron, Trained Astronaut Shannon Lucas, Retired Astronauts Zip Elvin and Colt Steelcase, Alien Hunting Specialist Ridley, Football player Uvininous "U-boat" Botango, News reporter Clark Sparkman (who instantly takes a fancy to Velma, much to her annoyance) and of course Fred Jones, Shaggy Rogers and Scooby-Doo. Fred allies himself with Zip and Colt, much to their dismay. Shaggy and Scooby are happy to see U-boat. Shannon tells Daphne that she scored the highest on the space test she and her friends took, much to Velma's surprise. This causes Velma to become bitter towards Daphne.
12 years after the TV series, Burt Gummer (Michael Gross) is now a star in his own series about survival, taking place in Perfection. He is approached by filmmaker Travis Welker, (Jamie Kennedy) who wants to help expand his brand, made famous by his series; he becomes Burt's new cameraman. Travis says he's from Florida, where Burt seems to have some history. Erick Van Wyk from the South African Wildlife Ministry asks them to deal with an Ass-Blaster problem. After Erick agrees to pay them for their services, Burt and Travis head to Africa to hunt down the creatures. Burt becomes friends with the pilot of their helicopter, Dan Bravers, who explains to him that a monster hunter and a monster have a strange attraction, reminding Burt of El Blanco. Burt is upset to find that South African gun laws have impounded the heavy weapons he was bringing. They arrive at the Cradlestone Reserve and meet Dreyer, who has tranquilizers to sedate and capture an Ass-Blaster. Burt has come prepared to find Graboids as well: "If you got Ass-Blasters, you got Graboids.
In 1988, following his mother's death, a young Peter Quill is abducted from Earth by the Ravagers, a group of space pirates led by Yondu Udonta. Twenty-six years later on the planet Morag, Quill steals an orb, after which Korath, a subordinate to the fanatical Kree, Ronan, intercepts him. Although Quill escapes with the orb, Yondu discovers his theft and issues a bounty for his capture, while Ronan sends the assassin Gamora after the orb.
An extraterrestrial visitor from outer space lands in a supermarket and decides to take the form of a schnitzel. Kobi Zucker (Neveh Tzur), a young teenage boy, is challenged by his love interest, Maya Kaplinski (Olga Bardukov), to retrieve something for her from within the supermarket. Craziness ensues when Kobi enters the supermarket and is confronted with "Schnitzel" the alien.
Mr. Peabody is a gifted anthropomorphic dog who has an adopted 7-year-old son, Sherman. He tutors Sherman travelling throughout history using the WABAC, a time machine.
April O'Neil (Megan Fox), a reporter for Channel 6 Eyewitness News in New York City, investigates a crime wave by criminals called the Foot Clan. At a dock at night, she sees the Foot raiding cargo containers. After an unseen vigilante attacks the thieves, April notices a symbol left behind. April's supervisor Bernadette Thompson (Whoopi Goldberg) and her coworkers are oblivious to her story. Later while covering a charity event thrown by Sacks Industries, April expresses gratitude to the company's CEO Eric Sacks (William Fichtner), who was her late father's (Paul Fitzgerald) lab partner.