In the 1920s, Sean Thornton (John Wayne), an Irish-born American from Pittsburgh, travels to Ireland to reclaim his family's farm and his birthplace in Inisfree. He meets and falls in love with the fiery Mary Kate Danaher (Maureen O'Hara), the sister of the bullying, loud-mouthed landowner Squire "Red" Will Danaher (Victor McLaglen). Danaher, who had wanted the farm himself, is angry that the Widow Tillane (herself angered by Danaher's admission that he had discussed her in the local pub) accepts Sean's bid, and retaliates by refusing consent for his sister to marry. Several town locals, including the Catholic priest, Father Lonergan (Ward Bond), conspire to trick him into believing that the wealthy Widow Tillane (Mildred Natwick) wants to marry him, but only if Mary Kate is no longer living in his house. After learning the truth on Sean and Mary Kate's wedding day, an enraged Will refuses to give his sister her dowry which is made up of a large sum of money and her family possessions passed down from her mother.
The drama charts the story of Midge Kelly (Kirk Douglas), a boxer who pushes himself to the top of his game by knocking out opponents and back-stabbing friends. He has no qualms about deceiving the various females he encounters and he eventually double-crosses Tommy Haley (Paul Stewart), the manager who found him and helped pave his road to fame.
Bill "Stoker" Thompson (Robert Ryan) is a 35-year-old has-been boxer about to take on an opponent at the fictional Paradise City Arena. His wife, Julie (Audrey Totter), fears that this fight may be his last and wants him to forfeit the match. Tiny (George Tobias), Stoker's manager, is sure he will continue to lose fights, so he takes money for a "dive" from a mobster, but is so certain of Stoker's failure that he does not inform the boxer of the set-up.
Charley Davis, against the wishes of his mother, becomes a boxer. As he becomes more successful the fighter becomes surrounded by shady characters, including an unethical promoter named Roberts, who tempt the man with a number of vices. Charley finds himself faced with increasingly difficult choices.
Tommy McCoy is a tough New York City boy, close to his dad, Brian, a performer in vaudeville. One night while his dad's doing a song and dance for the audience as part of a boxing event, Tommy accepts a challenge to step into the ring. He knocks out his opponent.
Well-meaning and mild-mannered milkman Burleigh Sullivan (Kaye) meets Polly Pringle (Mayo), a beautiful, but out-of-work, singer, whilst on his rounds early in the morning. He tries to get her a job at the club where his sister Susie (Vera-Ellen) is performing, but gets the sack for his trouble. Whilst meeting Susie after the show, he sees her being molested by drunken boxer 'Speed' McFarlane and his bodyguard 'Spider'. In the fracas, Speed is knocked out and his manager, Gabby Sloan, is furious.
In 1890s San Francisco, boxing is illegal. James J. Corbett (Errol Flynn), a brash young bank teller, attends a match with his friend Walter Lowrie (Jack Carson). When a police raid nets Judge Geary, a member of the board of directors of Corbett's bank, Corbett's fast talking gets his superior out of trouble. The judge is looking to improve the image of boxing by recruiting men from more respectable backgrounds and having them fight under the Marquess of Queensberry rules. He has even imported British coach Harry Watson (Rhys Williams) to evaluate prospects. Watson finds that Corbett, raised in a combative Irish immigrant family headed by Pat Corbett (Alan Hale), has excellent fighting skills; Geary likes his protégé's seemingly-polished manner.
After a brief history on the many different forms of manly arts through the years, Goofy demonstrates the different methods of boxing, as well as punching the bag and shadow boxing - literally - until finally he feels ready for the boxing ring.
Elinor Lee, a gangster’s moll living in the Harlem section of New York City, has signed up-and-coming boxer Benny Blue to a 10-year contract. Lee and a pair of corrupt fight promoter scheme to build up Blue as a potential champion, with the goal of betting against him when they force him to take a dive in a champion fight. Lee conspires to hire Fredi, an old friend of Blue and an escaped convict hiding from the law, to be his sweetheart and to control him for Lee and her partners.
In Florida, boxing promoter Nick Donati (Edward G. Robinson) gets doublecrossed by his boxer, who throws a fight for a $25,000 bribe from gangster Turkey Morgan (Humphrey Bogart). Nick and his girlfriend "Fluff" (Bette Davis) decide to throw a wild, days-long party with the money they have left, before looking for a new boxing prospect. Nick orders naive young farmer turned hotel bellhop Ward Guisenberry (Wayne Morris) to mix some drinks, but he does not know how, as he does not drink. Fluff kindly helps him out. When Morgan, underling Buzz Barret (Ben Welden), and Chuck McGraw (William Haade), his fighter and new heavyweight champion, arrive uninvited, Ward does not like it when the somewhat drunk McGraw pushes Fluff, so he punches him, knocking him to the ground. Nick is impressed, and persuades him to try boxing.
Kid Marc est un boxeur prometteur qui peut devenir champion d'Europe. Mais il se laisse séduire par Régina, une comédienne de théâtre égoïste et peu scrupuleuse, qui l'empêche de s'entrainer. Lors d'un combat important, Kid Marc, en manque de forme se fait battre. Régina le laisse tomber, mais la jeune Clairette, qui aime le boxeur, est là qui l'attend.