Sherlock Holmes is awakened in modern times from suspended animation as a result of an earthquake. He is aided in his recovery by Dr. Amy Winslow (Debrah Farentino), who lives in Baker Street in San Francisco. Holmes pits his wits against the descendants of the Moriarty family, led by James Moriarty Booth. He is also aided by a new group of Baker Street Irregulars led by Zapper (Mark Adair-Rios).
At the request of Inspector Lestrade (Colin Skinner), Sherlock Holmes (Patrick Macnee) investigates a double murder at the Strand Theatre, with the assistance of Dr John Watson (John Scott-Paget).
Londres, 1900. Alors qu'il va enfin être pendu, le professeur Moriarty, cerveau du crime et ennemi juré de Sherlock Holmes, parvient à s'enfuir. Il reprend aussitôt ses activités criminelles en volant un code secret utilisé par l'armée anglaise pour chiffrer ses communications militaires, code qu'il essaie de revendre au plus offrant, une fois la clé en sa possession. Moriarty enlève donc le créateur du code, le seul à en avoir la clé. Malheureusement pour Moriarty, il s'agit de Mycroft Holmes, frère aîné de Sherlock et éminence grise des services secrets...
Sherlock Holmes is a fictional character created by Dr. John Watson (Ben Kingsley) as the central character in a series of short stories published in Strand Magazine. Watson uses the character to enable him to solve crimes incognito, so as not to disrupt his career as a doctor during a period when he was applying for a post at an exclusive hospital, one in which the senior staff would frown on Watson's "hobby". Although he does not secure the job, Watson decides to satisfy public demand to see Holmes in person by hiring unemployed actor Reginald Kincaid (Michael Caine) to play the part of the fictional detective.
Le célèbre détective Sherlock Holmes et son fidèle Dr Watson sont appelés pour résoudre une effroyable malédiction qui poursuit la malheureuse famille des Baskerville, décimée par un monstrueux chien, sorti tout droit de l'enfer, depuis que Sir Hugo, un ancêtre, tua une paysanne. Mais l'héritier actuel, qui arrive d'Amérique, ne croit pas en ces fariboles.
In the beginning sequence, a former FBI agent named Carter Morstan (Barry Morse) receives an unwelcome visit by a man named Small. In the ensuing struggle, a gunshot rings. Subsequently, a body is wrapped into a carpet and set alight.
In London, circa 1897, a young mouse named Olivia Flaversham is celebrating her birthday with her toymaker father, Hiram. Suddenly, Fidget, a bat with a peg leg, barges in, and after a brief struggle, disappears with Hiram. Fidget takes Hiram to Professor Ratigan who commands him to create a clockwork robot which mimics the Queen of the Mice so Ratigan can rule England. Hiram initially refuses to participate in the scheme, but agrees when Ratigan threatens Olivia.
Teenagers Sherlock Holmes (Nicholas Rowe) and John Watson (Alan Cox) meet and become good friends as students at London's less-than-prestigious Brompton Academy. Watson is introduced to Holmes’ mentor, Rupert T. Waxflatter (Nigel Stock), a retired schoolmaster and inventor. Waxflatter's niece Elizabeth Hardy (Sophie Ward) is also Holmes’ close friend and love interest. Holmes is generally recognized as brilliant but considered an undisciplined troublemaker by most of the school administration. He is closest to Professor Rathe (Anthony Higgins), his fencing instructor, who warns Holmes that he is too emotional and impulsive.
The story takes place in 1913. Sherlock Holmes, virtually in retirement, is persuaded by Inspector Alec MacDonald of Scotland Yard to take on a baffling case. Three dead bodies have been found in London's East End, all with no discernible cause of death, but the expressions on their faces suggest that they all died in a state of terror.
Le Major Sholto a jadis pris possession du trésor caché par un Rajah, avec la complicité d'un de ses hommes et les informations données par Jonathan Small, un détenu. Mais il est rentré en Angleterre avec tout le butin.